Oxford Handbook of Nucleic Acid Structure (Oxford Handbooks)

This handbook of all aspects of nucleic acid structure emphasizes the results from X-ray crystallography and NMR studies. The contributors are authorities in their fields, and provide balanced surveys which cover underlying fundamentals as well as recent advances. 1. [data missing] 2. Polynucleotide secondary structures: an historical perspective 3. Base and base pair morphologies, helical parameters, and definitions 4. The nucleic acid database: a research and teaching tool 5. Simulation of nucleic acid structure 6. A-DNA duplexes in the crystal 7. Helix structure and molecular recognition by B-DNA 8. The single-crystal structures of Z-DNA 9. Standard DNA duplexes and RNA-DNA hybrids in solution 10. Nucleic acid hydration 11. Single crystal X-ray diffraction studies on the non Watson-Crick base associations of mismatches, modified bases, and non-duplex oligonucleotide structures 12. DNA mismatches in solution 13. Structures on nucleic acid triplexes 14. [data missing] 15. DNA bending by adenine-thymine tracts 16. Structures and interactions of helical junctions in nucleic acids 17. DNA higher-order structures 18. Crystallographic structures of RNA oligoribonucleotides and ribozymes 19. RNA structure in solution 20. Transfer RNA

The Oxford Handbook of Nucleic Acid Structure is a comprehensive reference on all aspects of nucleic acid structure, with particular emphasis on the results from X-ray crystallography and NMR studies. In nineteen chapters by leading experts, it describes in detail the variety of DNA and RNA structural types discovered to date, progressing systematically through the polymorphs of double helical DNA through to the higher-order organizations of triplexes, quadruplexes, and junctions, then to RNA structures in their various degrees of complexity.

Reviews secondary structures, morphologies, other considera- tions; research & training databases; schematic diagrams.

A comprehensive reference on art of aspects nucleic acid structure, with particular emphasis on results from X-ray crystallography and NMR studies. It describes in detail the structural types discovered to date.