Ovulation and its disorders : themes from the XIth World Congress on Fertility and Sterility, Dublin, June 1983, held under the auspices of the International Federation of Fertility Societies

This monograph contains a selection of papers presented at the Xlth World Congress of Fertility and Sterility (Dublin, 1983); the central theme is ovarian function and treatment of its disorders. Cross-cultural research provides international congresses with their unique quality due to the world-wide exchange of views; we think this aim has been achieved and reflected in this book. During the past decade significant advances have been made in our understanding of the events surrounding human ovulation leading to the development of an increasing range of effective therapeutic agents and the more logical use of existing drugs. As a result infertile patients with disordered ovulation can now anticipate a more favourable out­ come. In addition more sophisticated diagnostic methods have revealed the presence of minor defects in ovarian function in some patients previously labelled as 'unexplained infertility'. The identification of such problems can only lead to further therapeutic success. The contents of this volume reflect many different aspects of the study of ovulation including the monitoring of both follicular growth and the luteal phase, the role of prolactin and the treatment of ovulatory dysfunction. We are sure that the wide range of topics will evoke continued interest in these subjects. We extend our thanks to the invited speakers for their excellent contributions in lecture and essay form and express our gratitude for the unfailing help we received from the staff of MTP Press in the preparation of this volume. Front Matter....Pages i-xix Front Matter....Pages 1-1 Ultrasonic and endocrinologic monitoring of follicular growth during spontaneous and clomiphene stimulated cycles....Pages 3-6 The use of ultrasonography to detect ovulation....Pages 7-12 Ultrasound versus laparoscopy in the diagnosis of the LUF syndrome....Pages 13-19 Radioimmunoassay of progesterone in human saliva....Pages 21-25 Serum progesterone levels as a criterion of ovulation....Pages 27-29 How unexplained is the unexplained cause of infertility?....Pages 31-36 Opioid peptides effects on female fertility....Pages 37-41 Front Matter....Pages 43-43 Concentration of prostaglandin F in human peripheral venous plasma and in corpus luteum....Pages 45-48 Estimation of corpus luteum function using follicular phase plasma progesterone concentration....Pages 49-52 Analysis of luteal insufficiency in infertile women....Pages 53-57 Causes of plasma progesterone concentrations above the ‘normal’ range in the preovulatory phase....Pages 59-62 Premenstrual progesterone levels in menstrual cycles with short luteal phases....Pages 63-65 The trapped ovum — biochemical, ultrasonic and laparoscopic findings....Pages 67-71 Hormonal concentrations of serum and peritoneal fluid of women with unexplained infertility (LUF syndrome)....Pages 73-78 Origin of low peritoneal fluid steroid concentrations in the luteinized unruptured follicle syndrome....Pages 79-83 Front Matter....Pages 85-85 Stimulation of prolactin secretion by cimetidine, a histamine H 2 -receptor antagonist, in women....Pages 87-92 Effect of a dopamine agonist and metoclopramide on gonadotrophin release....Pages 93-98 Prolactin and receptor capacity of the human corpus luteum....Pages 99-103 Discrepancy of endometrial dating in the mid-luteal phase of hyperprolactinaemic women....Pages 105-107 Methergoline therapy of amenorrhoea and sterility in women with normal prolactin secretion....Pages 109-111 Front Matter....Pages 85-85 Long-term follow up of the female hyperprolactinaemic syndrome treated with bromocriptine....Pages 113-116 Metergoline and bromocriptine in the management of tumoural and idiopathic hyperprolactinaemia....Pages 117-121 Clomiphene citrate and bromocriptine versus placebo in the treatment of idiopathic infertile couples....Pages 123-127 Front Matter....Pages 129-129 Induction of ovulation in hypothalamic amenorrhoea with gonadotrophin releasing hormone....Pages 131-134 Induction of ovulation with purified urinary FSH in patients affected by PCOS....Pages 135-138 Induction of ovulation with the anti-oestrogen tamoxifen....Pages 139-142 Prednisolone-clomiphene treatment in patients who fail to respond to clomiphene — role of prednisolone....Pages 143-146 Serum oestradiol values after extended clomiphene citrate therapy....Pages 147-151 Sex ratio of infants born following induction of ovulation....Pages 153-155 Monitoring ovulation induction with hMG/hCG by oestrogen determination and ultrasonography....Pages 157-161 A comparison of two methods for monitoring gonadotrophin therapy....Pages 163-166 Repetitivity and therapy of luteinized unruptured follicle syndrome....Pages 167-171 Antibiotic therapy for luteal phase defect and premenstrual syndrome....Pages 173-179 Back Matter....Pages 181-185