Organophosphorus Reagents: A Practical Approach In Chemistry (the Practical Approach In Chemistry Series)

Organophosphorus Chemistry: A Practical Approach in Chemistry provides a practical introduction to the field by mixing a brief review of the subject area with key experimental details and sample procedures. Phosphorus is an element that has been central to the development of our modern way of life. Its chemistry plays a key role in the development of such important areas as pharmaceuticals, agrochemicals, modern materials and molecular biology. Much of this work requires a sound understanding of the organic chemistry of phosphorus and this volume is designed to instruct the reader in the essential methodology used. Topics covered include phosphines, applications of phosphorus (III) and (V) compounds as reagents in synthesis, the chemistry of phosphorus ylides, applications of the Wittig reaction in the synthesis of heterocyclic and carbocyclic compounds, preparation of Iminophosphoranes and their synthetic applications in the aza-Wittig reaction, phospho-transfer processes leading to [P-C] bond formation, low valent phosphorus compounds and phosphorus methods in oligonucleotide chemistry. It is intended not only for the specialist in organophosphorus chemistry, but also for the organic chemist with little experience in the field who wishes to add phophorus-based techniques to his or her ensemble of synthetic methods. Organophosphorus Reagents: A Practical Approach In Chemistry Provides A Practical Introduction To The Field By Mixing A Brief Review Of The Subject Area With Key Experimental Details And Sample Procedures. Phosphorus Is An Element That Bas Been Central To The Development Of Our Modern Way Of Life. Its Chemistry Plays A Key Role In The Development Of Such Important Areas As Pharmaceuticals, Agrochemicals, Modern Materials And Molecular Biology. Much Of This Work Requires A Sound Understanding Of The Organic Chemistry Of Phosphorus And This Volume Is Designed To Instruct The Reader In The Essential Methodology Used. It Is Intended Not Only For The Specialist In Organophosphorus Chemistry, But Also For The Organic Chemist With Little Experience In The Field Who Wishes To Add Phosphorus-based Techniques To His Or Her Ensemble Of Synthetic Methods.--book Jacket. Organophosphorus Chemistry / Patrick J. Murphy -- The Synthesis And Applications Of Phosphines / Matthew L. Clarke And Jonathan M.j. Williams -- Applications Of Phosphorus (iii) And (v) Compounds As Reagents In Synthesis / R. Alan Aitken And Nazira Karodia -- The Wittig And Related Reactions / Andrew D. Abell And Michael K. Edmonds -- Applications Of The Wittig Reaction In The Synthesis Of Heterocyclic And Carbocyclic Compounds / Rainer Schobert -- Preparation And Reactions Of Iminophosphoranes And Their Synthetic Applications In The Aza-wittig Reaction / J. Mike Southern And Ian A. O'neil -- Phospho-transfer Processes Leading To [p-c] Bond Formation / Matthew D. Fletcher -- Low-coordinated Phosphorus Compounds / Sven Asmus, Uwe Bergstrasser, Heinrich Heydt, Marion Schmitz And Manfred Regitz -- Phosphorus Methods In Nucleotide Chemistry / David M. Williams And Vicki H. Harris. Edited By Patrick J. Murphy. Includes Bibliographical References And Index. Phosphorus plays a key role in the development of such important areas as pharmaceuticals, agrochemicals, modern materials and molecular biology. This volume is intended for the specialist in organophosphorus chemistry, and also as an introduction for the organic chemist with little experience in the field.