Organofluorine Compounds in Biology and Medicine

This book covers topics on biochemically relevant organofluorine compounds and their synthesis and biochemical pathways. Organofluorine compounds have renewed interest in pharmaceutical industry, and therefore a concise book on this topic is highly relevant to the scientific community involved in this area. Covers the synthesis, biochemical, and therapeutic applications of organofluorine compounds Offers a complete text on biochemically relevant organofluorine compounds and their synthesis and mechanistic pathways Provides one of the first major reference books on the biological and medicinal applications of organofluorine chemistry Content: Front Matter, Page iii Copyright, Page iv Dedication, Page v Short Biography, Page xiii Preface, Pages xv-xvi Importance of this Book, Page xvii Chapter 1 - General Aspects of Organofluorine Compounds, Pages 1-27 Chapter 2 - Fluorinated Compounds in Enzyme-Catalyzed Reactions, Pages 29-57 Chapter 3 - Synthetic Methods, Pages 59-100 Chapter 4 - Fluorinated Amino Acids, Peptides, and Proteins, Pages 101-132 Chapter 5 - Organofluorine Pharmaceuticals, Pages 133-178 Chapter 6 - Organofluorine Anesthetics, Pages 179-199 Chapter 7 - Organofluorine Compounds as Positron Emission Tomography Tracers, Pages 201-240 Chapter 8 - Organofluorine Compounds in Neurological Disorders, Pages 241-263 Chapter 9 - Organofluorine Compounds as Anticancer Agents, Pages 265-300 Index, Pages 301-312 Organofluorine Compounds in Biology and Medicine covers topics on biochemically relevant organofluorine compounds and their synthesis and biochemical pathways. Organofluorine compounds have renewed interest in pharmaceutical industry, and therefore a concise book on this topic is highly relevant to the scientific community involved in this area. Covers the synthesis, biochemical, and therapeutic applications of organofluorine compounds Offers a complete text on biochemically relevant organofluorine compounds and their synthesis and mechanistic pathways Provides one of the first major reference books on the biological and medicinal applications of organofluorine chemistry La 4e de couverture indique: "Organofluorine Compounds in Biology and Medicine contains cutting-edge developments and future prospects of fluorine in bioorganic and medicinal chemistry, and is essential for researchers who want to take advantage of the use of fluorine in biomedical research, from rational drug design and synthesis to the use of fluorine labels as proves in metabolic study, protein engineering, and clinical diagnosis. It is also appropriate at the university level as a reference for courses in organic synthesis, advanced organic chemistry, and in biochemistry"

This book covers topics on biochemically relevant organofluorine compounds and their synthesis and mechanistic pathways. Organofluorine compounds have renewed interest in pharmaceutical industry, and therefore a concise book on this topic is highly relevant to the scientific community involved in this area.

• Lists all FFDA approved fluorine based therapeutics
• Contains active structures and Gaussian program to calculate the structure characteristics of all compounds
• Explains the mechanistic of all biochemical reactions

"Organofluorine Compounds in Biology and Medicine contains cutting-edge developments and future prospects of fluorine in bioorganic and medicinal chemistry, and is essential for researchers who want to take advantage of the use of fluorine in biomedical research, from rational drug design and synthesis to the use of fluorine labels as proves in metabolic study, protein engineering, and clinical diagnosis. It is also appropriate at the university level as a reference for courses in organic synthesis, advanced organic chemistry, and in biochemistry"--Back cover Covers the synthesis, biochemical and therapeutic applications of organo fluorine compounds. This book covers topics on biochemically relevant organofluorine compounds and their synthesis and mechanistic pathways. It contains active structures and Gaussian program to calculate the structure characteristics of various compounds.