Organ Allocation : Proceedings of the 30th Conference on Transplantation and Clinical Immunology, 2–4 June, 1998

Over the last few years, transplantation knowledge and techniques, as well as insights into pharmacology, have improved, thus enabling greater access to transplantation for patients. The pool of organs for transplantation is stable, and therefore insufficient to cope with the growing demand. To adjust demand and resources in the most equitable way, organ procurement and allocation have been organized nationally and often across borders. The national and international organ exchange programs were studied and discussed during the Congress on Organ Allocation, from which this book is derived. This book describes the state of the art in the management of waiting lists and the allocation of organs in transplantation. It includes chapters on the possibilities of expanding the pool of available cadaver organs. It also analyzes the results of transplantation of cadaver organs from older donors and marginal, non-heart beating donors. Transplantation policies based on the offering of organs by living donors are also described, as is the impact of delayed graft function on organ allocation. Front Matter....Pages i-xi Front Matter....Pages 1-1 Principles for allocation of cadaver organs to transplant recipients and coordinating procedures in Spain....Pages 3-21 Principles and practice of cadaver organ allocation in France....Pages 23-28 Principles for allocation of cadaver organs to transplant recipients in Italy....Pages 29-36 Allocation of cadaver organs to transplant recipients in Scandiatransplant....Pages 37-44 Principles for allocation of cadaver organs to transplant recipients in the USA (UNOS)....Pages 45-50 Allocation of kidneys in the UK....Pages 51-54 Front Matter....Pages 55-55 What to expect from a good kidney allocation system....Pages 57-60 Allocation of cadaver organs to transplant recipients in Eurotransplant: principles and policies, Anno 1998....Pages 61-66 Increasing kidney supply as the best solution to the allocation problem....Pages 67-72 Strategies in organ donation....Pages 73-81 World Health Organization guidelines on transplantation and the WHO Task Force....Pages 83-94 Front Matter....Pages 95-95 The French liver transplant waiting list: 5-year analysis (1992–1996)....Pages 97-116 Predictors of multiple listing for cadaver kidney transplantation and the effects of a ban on multiple listing in the United States — a summary....Pages 117-131 Allocation of kidneys to patients on the transplant waiting list: a simulation-based policy model....Pages 133-133 Factors influencing early placement on the kidney transplant waiting list in the United States....Pages 135-137 The organ transplant waiting list in France....Pages 139-143 Front Matter....Pages 145-145 Expanded donor pool....Pages 147-166 Non-heart-beating donors....Pages 167-168 How to reconcile viral safety and efficacy in organ procurement....Pages 169-173 The problem of infectious transmission from donors in organ transplantation....Pages 175-176 Front Matter....Pages 145-145 Further readings on allocation of organs from at-risk donors....Pages 177-177 Front Matter....Pages 179-179 The inflammatory cascade of liver ischemia and reperfusion: from the donor to the recipient....Pages 181-208 The role of T-cell costimulatory pathways in ischemia—reperfusion injury....Pages 209-214 Interest in an anti-LFA-1 monoclonal antibody in the prevention of reperfusion injury in kidney transplantation....Pages 215-223 Preservation solution in heart transplantation....Pages 225-232 The impact of ischemia-reperfusion injury on specific and non-specific, early and late chronic events after organ transplantation....Pages 233-260 Pharmacological intervention to decrease ischemia-reperfusion injury....Pages 261-266 Front Matter....Pages 267-267 Organ transplantation in Islam....Pages 269-272 Live donor transplantation in Sweden and other Nordic countries with emphasis on the benefits of the procedure....Pages 273-284 Kidney exchange programs: an expanded view of the ethical issues....Pages 285-295 Unconventional living kidney donors....Pages 297-309 Back Matter....Pages 311-311 Proceedings of the 30th International Conference on Transplantation and Clinical Immunology, 2-4 June 1998