Ophthalmic Drug Delivery Systems, Second Edition (Drugs and the Pharmaceutical Sciences: a Series of Textbooks and Monographs)

Extensively revised and updated, this second edition compares conventional and innovative drug delivery systems. The book covers significant ophthalmic advances and breakthroughs in gene therapy, ocular microdialysis, vitreous drug disposition modelling, and receptor/transporter targeted drug delivery. It examines procedures in pharmacokinetic/pharmacodynamic modeling for the determination of appropriate dosing regimens, covers new developments in animal modeling, and discusses current regulations governing patenting, commercial product release, and human testing. This in-depth reference lays the groundwork for overcoming constraints on the delivery of ophthalmic drugs. "Extensively revised and expanded throughout, the Second Edition compares conventional and innovative drug delivery systems ... examines procedures in pharmacokinetic/pharmacodynamic modeling for the determination of appropriate dosing regimens ... covers new developments in animal modeling ... and considers current regulations governing patenting, commercial product release, and human testing."--BOOK JACKET The second edition of this text assembles significant ophthalmic advances and encompasses breakthroughs in gene therapy, ocular microdialysis, vitreous drug disposition modelling, and receptor/transporter targeted drug delivery. Opthalmic drug delivery is one of the most interesting and challenging endeavors facing the pharmaceutical scientist.