Oogenesis : The Universal Process

Oogenesis - the process by which female germ cells develop into mature eggs, or ova - is a complex process involving many important elements of developmental and cellular biology: from cell-cell interactions, complex signalling cascades, specialized cell cycles and cytoskeleton organization. Oocytes from various species (including clam, starfish, xenopus and mouse) are excellent model systems to study the biochemistry of cell division with important implications for basic and clinical research. This book describes the entire process of oogenesis in chronological order with contributions from leading international researchers and chapters covering medical and ethical considerations in oogenic biology. Topics include sex determination and gonadal development, control of meiotic chromosome pairing and homologous recombination, control of meiotic divisions and the remodelling of the oocyte into a totipotent zygote as well as medically-assisted reproduction. This volume is an essential resource for all students, researchers and clinicians in developmental and reproductive biology. Key features: Reaches beyond the study of simply meiosis to cover all aspects of oogenesis Synthesizes recent advances in the field, drawing on studies from different model species Chapter sequence designed to follow the time line in vivo Written by an international panel of expert researchers Content: Chapter 1 The Sperm/Oocyte Decision, a C. elegans Perspective (pages 1–26): Ronald Ellis Chapter 2 Sex Determination and Gonadal Development (pages 27–79): Alexander Combes, Cassy Spiller and Peter Koopman Chapter 3 Clytia hemisphaerica: A Cnidarian Model for Studying Oogenesis (pages 81–101): Aldine Amiel, Patrick Chang, Tsuyoshi Momose and Evelyn Houliston Chapter 4 Soma–Germline Interactions in the Ovary: An Evolutionary Perspective (pages 103–113): David Albertini and John Bromfield Chapter 5 Homologous Chromosome Pairing and Synapsis during Oogenesis (pages 115–140): Susanna Mlynarczyk?Evans and Anne Villeneuve Chapter 6 Meiotic Recombination in Mammals (pages 141–177): Sabine Santucci?Darmanin and Frederic Baudat Chapter 7 Initiation of the Meiotic Prophase?to?Metaphase Transition in Mammalian Oocytes (pages 179–197): Laurinda A. Jaffe and Rachael P. Norris Chapter 8 Oocyte?Specific Translational Control Mechanisms (pages 199–226): Isabel Novoa, Carolina Eliscovich, Eulalia Belloc and Rau??l Mendez Chapter 9 MPF and the Control of Meiotic Divisions: Old Problems, New Concepts (pages 227–265): Catherine Jessus Chapter 10 Meiotic Spindle Assembly and Chromosome Segregation in Oocytes (pages 267–290): Julien Dumont and Stephane Brunet Chapter 11 Mechanisms of Asymmetric Division in Metazoan Meiosis (pages 291–310): Marie?Helene Verlhac and Karen Wingman Lee Chapter 12 The Control of the Metaphase?to?Anaphase Transition in Meiosis I (pages 311–341): M. Emilie Terret Chapter 13 Mechanisms Controlling Maintenance and Exit of the CSF Arrest (pages 343–355): Thierry Lorca and Anna Castro Chapter 14 Cytostatic Arrest: Post?Ovulation Arrest until Fertilization in Metazoan Oocytes (pages 357–384): Tomoko Nishiyama, Kazunori Tachibana and Takeo Kishimoto Chapter 15 Mammalian Oocyte Population throughout Life (pages 385–401): Roger Gosden, Eujin Kim, Bora Lee, Katia Manova and Malcolm Faddy Chapter 16 Fertilization and the Evolution of Animal Gamete Proteins (pages 403–421): Julian L. Wong and Gary M. Wessel Chapter 17 Remodelling the Oocyte into a Totipotent Zygote: Degradation of Maternal Products (pages 423–446): Jose?Eduardo Gomes, Jorge Merlet, Julien Burger and Lionel Pintard Chapter 18 Chromatin Remodelling in Mammalian Oocytes (pages 447–478): Rabindranath De La Fuente, Claudia Baumann, Feikun Yang and Maria M. Viveiros Chapter 19 Follicles and Medically Assisted Reproduction (pages 479–489): Susan L. Barrett and Teresa K. Woodruff Oogenesis - the process by which female germ cells develop into mature eggs, or ova - is a complex process involving many important elements of developmental and cellular biology: from cell-cell interactions, complex signalling cascades, specialized cell cycles and cytoskeleton organization. Oocytes from various species (including clam, starfish, xenopus and mouse) are excellent model systems to study the biochemistry of cell division with important implications for basic and clinical research. This book describes the entire process of oogenesis in chronological order with contributions from leading international researchers and chapters covering medical and ethical considerations in oogenic biology. Topics include sex determination and gonadal development, control of meiotic chromosome pairing and homologous recombination, control of meiotic divisions and the remodelling of the oocyte into a totipotent zygote as well as medically-assisted reproduction. This volume is an essential resource for all students, researchers and clinicians in developmental and reproductive biology. **Key features:** * Reaches beyond the study of simply meiosis to cover all aspects of oogenesis * Synthesizes recent advances in the field, drawing on studies from different model species * Chapter sequence designed to follow the time line __in vivo__ * Written by an international panel of expert researchers Content: Chapter 1 The Sperm/Oocyte Decision, a C. elegans Perspective (pages 1–26): Ronald EllisChapter 2 Sex Determination and Gonadal Development (pages 27–79): Alexander Combes, Cassy Spiller and Peter KoopmanChapter 3 Clytia hemisphaerica: A Cnidarian Model for Studying Oogenesis (pages 81–101): Aldine Amiel, Patrick Chang, Tsuyoshi Momose and Evelyn HoulistonChapter 4 Soma–Germline Interactions in the Ovary: An Evolutionary Perspective (pages 103–113): David Albertini and John BromfieldChapter 5 Homologous Chromosome Pairing and Synapsis during Oogenesis (pages 115–140): Susanna Mlynarczyk?Evans and Anne VilleneuveChapter 6 Meiotic Recombination in Mammals (pages 141–177): Sabine Santucci?Darmanin and Frederic BaudatChapter 7 Initiation of the Meiotic Prophase?to?Metaphase Transition in Mammalian Oocytes (pages 179–197): Laurinda A. Jaffe and Rachael P. NorrisChapter 8 Oocyte?Specific Translational Control Mechanisms (pages 199–226): Isabel Novoa, Carolina Eliscovich, Eulalia Belloc and Rau??l MendezChapter 9 MPF and the Control of Meiotic Divisions: Old Problems, New Concepts (pages 227–265): Catherine JessusChapter 10 Meiotic Spindle Assembly and Chromosome Segregation in Oocytes (pages 267–290): Julien Dumont and Stephane BrunetChapter 11 Mechanisms of Asymmetric Division in Metazoan Meiosis (pages 291–310): Marie?Helene Verlhac and Karen Wingman LeeChapter 12 The Control of the Metaphase?to?Anaphase Transition in Meiosis I (pages 311–341): M. Emilie TerretChapter 13 Mechanisms Controlling Maintenance and Exit of the CSF Arrest (pages 343–355): Thierry Lorca and Anna CastroChapter 14 Cytostatic Arrest: Post?Ovulation Arrest until Fertilization in Metazoan Oocytes (pages 357–384): Tomoko Nishiyama, Kazunori Tachibana and Takeo KishimotoChapter 15 Mammalian Oocyte Population throughout Life (pages 385–401): Roger Gosden, Eujin Kim, Bora Lee, Katia Manova and Malcolm FaddyChapter 16 Fertilization and the Evolution of Animal Gamete Proteins (pages 403–421): Julian L. Wong and Gary M. WesselChapter 17 Remodelling the Oocyte into a Totipotent Zygote: Degradation of Maternal Products (pages 423–446): Jose?Eduardo Gomes, Jorge Merlet, Julien Burger and Lionel PintardChapter 18 Chromatin Remodelling in Mammalian Oocytes (pages 447–478): Rabindranath De La Fuente, Claudia Baumann, Feikun Yang and Maria M. ViveirosChapter 19 Follicles and Medically Assisted Reproduction (pages 479–489): Susan L. Barrett and Teresa K. Woodruff Oogenesis - the process by which female germ cells develop into mature eggs, or ova - is a complex process involving many important elements of developmental and cellular biology: from cell-cell interactions, complex signalling cascades, specialized cell cycles and cytoskeleton organization. Oocytes from various species (including clam, starfish, xenopus and mouse) are excellent model systems to study the biochemistry of cell division with important implications for basic and clinical research. This book describes the entire process of oogenesis in chronological order with contributions from leading international researchers and chapters covering medical and ethical considerations in oogenic biology. The topics include sex determination and gonadal development, control of meiotic chromosome pairing and homologous recombination, control of meiotic divisions and the remodelling of the oocyte into a totipotent zygote as well as medically-assisted reproduction. This volume is an essential resource for all students, researchers and clinicians in developmental and reproductive biology. It reaches beyond the study of simply meiosis to cover all aspects of oogenesis. It synthesizes recent advances in the field, drawing on studies from different model species. The chapter sequence is designed to follow the time line in vivo. It is written by an international panel of expert researchers