Oncogenes in B-Cell Neoplasia : Workshop at the National Cancer Institute, National Institutes of Health, Bethesda, MD, USA, March 5–7, 1984

reprint of the hardcover 1st edition 1984 Library of Congress Catalog Card Number 15-12910 The use of registered names, trademarks, etc. in this pUblication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product Liability: The publisher can give no guarantee for information about drug dosage and application thereof contained in this bo9k. In every individual case the respective user must check its accuracy by consulting other pharmaceutical literature. Front Matter....Pages I-XIII Introductory Remarks....Pages 1-5 Activated Oncogenes in Burkitt’s Lymphoma....Pages 6-14 Detection of an Adenovirus E1A-like Activity in Mammalian Cells....Pages 15-19 Does the Large T Protein of Polyoma Virus Regulate the Expression of the Cellular myc Gene?....Pages 20-25 Genome Structure and Host Range Restriction of the Lymphotropic Papovavirus (LPV): Identification of a Viral Lymphocyte Specific Enhancer Element....Pages 26-30 Tlym-I, a Stage Specific Transforming Gene Shares Homology with MHC I Region Genes....Pages 31-33 Structural and Functional Analysis of ras and Blym Oncogenes....Pages 34-36 Structural Organization of Mouse c-myb Locus and the Mechanism of its Rearrangement in ABPL-2 Tumor Line Induced by Pristane and Abelson Murine Leukemia Virus....Pages 37-40 Disruption and Activation of the c-myb Locus by M-MuLV Insertion in Plasmacytoid Lymphosarcomas Induced by Pristane and Abelson Viruses....Pages 41-46 Follicular Hyperplasia in the Prelymphomatous Avian Bursa: Relationship to the Incidence of B-Cell Lymphomas....Pages 47-55 Multiple Steps in the Transformation of Normal B Cells Towards Neoplasia....Pages 56-61 Transferrin Receptors Regulate Proliferation of Normal and Malignant B Cells....Pages 62-68 Cloned Neoplastic B Cells Release a Growth Factor Which Augments Lymphokine-Mediated Proliferation of Normal B Cells....Pages 69-71 The Action of an Lyb2.1-Specific Monoclonal Antibody in Soluble or Immobilized Form on Resting and Activated B Cells....Pages 72-76 T Cell Factors Regulating B Cell Activation and Differentiation....Pages 77-85 Interleukin 3 Dependent Retrovirus Induced Lymphomas: Loss of the Ability to Terminally Differentiate in Response to Differentiation Factors....Pages 86-91 Growth Regulation of a B-Cell Lymphoma via the Antigen Receptor....Pages 92-95 Interleukin-2 Receptors on Activated Malignant and Normal B-Cells....Pages 96-101 Immuno Affinity Purified Interleukin 2 (IL2) Induces B Cell Growth....Pages 102-103 Factors Affecting Normal and Malignant B Lymphocyte Precursors....Pages 104-108 Immunoglobulin Heavy Chain Switching in Cultured I.29 Murine B Lymphoma Cells: Commitment to an IgA or IgE Switch....Pages 109-116 The Regulation of c-myc by Growth Signals....Pages 117-126 Immune Regulation of the c-myc Oncogene in a Murine B Lymphoma....Pages 127-132 The Translocated c-myc Oncogene of Burkitt Lymphoma is Differentially Regulated in Lymphoblastoid vs Plasma Cells....Pages 133-145 Modes of c-myc Oncogene Activation in Murine Plasmacytomas....Pages 146-153 DNA Sequences Involved in the Rearrangement and Expression of the Murine c-myc Gene....Pages 154-160 Activation of the c-myc Oncogene in B and T Lymphoid Tumors....Pages 161-165 The c-myc Gene Paradox in Burkitt’s Lymphoma Chromosomal Translocation....Pages 166-171 Amplification, Expression and Rearrangement of c-myc and N-myc Oncogenes in Human Lung Cancer....Pages 172-175 Chromosomal Aberrations in Murine Plasmacytomas....Pages 178-182 Chromatin Structural Changes in the Putative Regulatory Region of c-myc Accompany the Translocation in a Burkitt Lymphoma....Pages 183-189 Aberrant Rearrangements at the Murine Light Chain Locus in Plasmacytomas....Pages 190-191 myc-Encoded Proteins of Chickens and Men....Pages 192-197 Properties of the myc-Gene Product: Nuclear Association, Inhibition of Transcription and Activation in Stimulated Lymphocytes....Pages 198-207 Introduction to Long-Term Cultures of Normal B Lymphocytes....Pages 208-209 Characteristics of Continuous in vitro Lines of BALB/c and NZB B Cells....Pages 210-216 Development of Cells of the B-Lymphocyte Lineage in Longterm Culture....Pages 217-223 Coexpression of Lyb-2 and Mac-1 by Murine Lymphomas and Subpopulations of Normal Spleen and Bone Marrow Cells....Pages 224-230 Ly-1 as a Differentiation Antigen on Normal and Neoplastic B Cells....Pages 231-236 Propagation of B Lymphocytes in Vitro....Pages 237-240 Identification of a Transforming Virus from a Lymphoma of a Mouse Infected with a Wild Mouse Retrovirus....Pages 241-249 Transformation Capacities of a Murine Retrovirus Encoding an Avian myc Oncogene....Pages 250-250 The CH Series of Murine B Cell Lymphomas: Identification of Cross-reactive Idiotypes and Restricted Antigen Specificities....Pages 251-257 Interaction of Acute Transforming Retroviruses with Murine Hematopoietic Cells....Pages 258-264 Monoclonal Antibody to Abelson Lymphoma Cells....Pages 265-268