Ocular Angiogenesis: Diseases, Mechanisms, and Therapeutics (Ophthalmology Research)

Leading academic and pharmaceutical researchers and clinicians from many disciplines synthesize and summarize current clinical and basic knowledge concerning abnormal growth of blood vessels in the eye, the cause of major neovascular eye diseases. The authors also identify and assess the most promising approaches with potential for commercial exploitation and discuss the challenges encountered in developing therapeutics for ocular neovascular diseases. Highlights include illuminating chapters on gene therapy and novel drug delivery systems and excellent summaries of the newest therapeutic approaches. A companion CD contains color versions of important figures used in the book. Summarizes the current knowledge of the etiologies and pathogenesis of the major neovascular diseases of the eye. In addition, it reviews the current understanding of the molecular regulation of blood vessel growth, while discussing the advantages and disadvantages of current therapeutic approaches to combat ocular neovascular diseases.