Obesity and Metabolism (Frontiers of Hormone Research, Vol. 36)

It has become increasingly difficult to keep up with the growing body of literature on the genetics, metabolic phenotype and treatment of obesity. This volume brings together an array of chapters from many of the foremost authorities and researchers in this area. Key advances in the genetics of obesity are summarized and the effects of obesity in pregnancy, childhood and old age explored. By scrutinizing the hormones and enzymes most recently implicated in the development, maintenance and consequences of obesity, the biochemical and physiological background of the abnormal metabolism of obesity is mapped out. Furthermore, a practical update on clinical approach and treatment of obesity is offered. Finally, the social aspects of obesity and the view of the obese body in art throughout the centuries are reflected. A valuable overview of causes, metabolic disturbances and treatment options, this volume will appeal to those with an interest in clinical as well as pathophysiological and genetic aspects of obesity. Furthermore, it will provide useful reading for scientists and students who would like to broaden and update their knowledge in this area. the zone......Page 1 Preliminary Pages.pdf......Page 2 01 Monogenic Human Obesity.pdf......Page 12 02 Polygenic Contribution to Obesity- Genome-Wide Strategies Reveal New Targets.pdf......Page 23 03 Genetic Obesity Syndromes.pdf......Page 48 04 Fetal and Neonatal Pathways to Obesity.pdf......Page 72 05 Developmental Origins of Obesity and the Metabolic Syndrome- The Role of Maternal Obesity.pdf......Page 84 06 Childhood Obesity.pdf......Page 96 07 Obesity in Old Age.pdf......Page 108 08 Models of ‘Obesity’ in Large Animals and Birds.pdf......Page 118 09 The -Cell in Type 2 Diabetes and in Obesity.pdf......Page 129 10 Role of the Endocannabinoid System in Energy Balance Regulation and Obesity.pdf......Page 146 11 11-Hydroxysteroid Dehydrogenase Type 1 and Obesity.pdf......Page 157 12 Gut and Hormones and Obesity.pdf......Page 176 13 Adipokines in Obesity.pdf......Page 193 14 The Role of AMP-Activated Protein Kinase in Obesity.pdf......Page 209 15 Classical Endocrine Diseases Causing Obesity.pdf......Page 223 16 Emerging Concepts in the Medical and Surgical Treatment of Obesity.pdf......Page 240 17 The Sociology of Obesity.pdf......Page 271 18 Obesity in Art – A Brief Overview.pdf......Page 282 Author Index.pdf......Page 298 Subject Index.pdf......Page 299 Monogenic human obesity-- Farooqi, I.S. Polygenic contribution to obesity : genome-wide strategies reveal new targets-- Korner, A. [et al.] Genetic obesity syndromes-- Goldstone, A. P., Beales, P. L. Fetal and neonatal pathways to obesity-- Gluckman, P. D. [et al.] Developmental origins of obesity and the metabolic syndrome : the role of maternal obesity-- Armitage, J. A., Poston, L., Taylor, P. D. Childhood obesity-- Sabin, M. A., Shield, J. P. H Obesity in old age-- McPhee Chapman, I. Models of obesity in large animals and birds-- Clarke, I. J. The [beta]-cell in type 2 diabetes and in obesity-- Rutter, G. A., Parton, L. E. Role of the endocannabinoid system in energy balance regulation and obesity-- Cota, D. 11[beta]-hydroxysteroid dehydrogenase type 1 and obesity-- Morton, N. M., Seckl, J. R. Gut and hormones and obesity-- Wren, A. M. Adipokines in obesity-- Ahima, R. S., Osei, S. Y. The role of AMP-activated protein kinase in obesity-- Kola, B., Grossman, A. B., Korbonits, M. Classical endocrine diseases causing obesity-- Weaver, J. U. Emerging concepts in the medical and surgical treatment of obesity-- Aylwin, S., Al-Zaman, Y. The sociology of obesity-- Rosengren, A., Lissner, L. Obesity in art--a brief overview-- Woodhouse, R. Monogenic human obesity / Farooqi, I.S. Polygenic contribution to obesity : genome-wide strategies reveal new targets / Korner, A. ... [et al.] Genetic obesity syndromes / Goldstone, A.P., Beales, P.L. Fetal and neonatal pathways to obesity / Gluckman, P.D. ... [et al.] Developmental origins of obesity and the metabolic syndrome : the role of maternal obesity / Armitage, J.A., Poston, L., Taylor, P.D. Childhood obesity / Sabin, M.A., Shield, J.P.H. Obesity in old age / McPhee Chapman, I. Models of obesity in large animals and birds / Clarke, I.J. The [beta]-cell in type 2 diabetes and in obesity / Rutter, G.A., Parton, L.E. Role of the endocannabinoid system in energy balance regulation and obesity / Cota, D. 11[beta]-hydroxysteroid dehydrogenase type 1 and obesity / Morton, N.M., Seckl, J.R. Gut and hormones and obesity / Wren, A.M. Adipokines in obesity / Ahima, R.S., Osei, S.Y. The role of AMP-activated protein kinase in obesity / Kola, B., Grossman, A.B., Korbonits, M. Classical endocrine diseases causing obesity / Weaver, J.U. Emerging concepts in the medical and surgical treatment of obesity / Aylwin, S., Al-Zaman, Y. The sociology of obesity / Rosengren, A., Lissner, L. Obesity in art a brief overview / Woodhouse, R. the zone 1 Obesity and Metabolism.pdf 2 Preliminary Pages.pdf 2 01 Monogenic Human Obesity.pdf 12 02 Polygenic Contribution to Obesity- Genome-Wide Strategies Reveal New Targets.pdf 23 03 Genetic Obesity Syndromes.pdf 48 04 Fetal and Neonatal Pathways to Obesity.pdf 72 05 Developmental Origins of Obesity and the Metabolic Syndrome- The Role of Maternal Obesity.pdf 84 06 Childhood Obesity.pdf 96 07 Obesity in Old Age.pdf 108 08 Models of ‘Obesity’ in Large Animals and Birds.pdf 118 09 The -Cell in Type 2 Diabetes and in Obesity.pdf 129 10 Role of the Endocannabinoid System in Energy Balance Regulation and Obesity.pdf 146 11 11-Hydroxysteroid Dehydrogenase Type 1 and Obesity.pdf 157 12 Gut and Hormones and Obesity.pdf 176 13 Adipokines in Obesity.pdf 193 14 The Role of AMP-Activated Protein Kinase in Obesity.pdf 209 15 Classical Endocrine Diseases Causing Obesity.pdf 223 16 Emerging Concepts in the Medical and Surgical Treatment of Obesity.pdf 240 17 The Sociology of Obesity.pdf 271 18 Obesity in Art – A Brief Overview.pdf 282 Author Index.pdf 298 Subject Index.pdf 299