Obesity and Diabetes : New Surgical and Nonsurgical Approaches

This timely and clinically oriented book uniquely addresses the entire spectrum of treatment for severe obesity and diabetes. It thoroughly examines all aspects from robotic surgery to cell therapy, from the latest antidiabetic drugs to endoscopic procedures and devices, from appetite-inhibiting signals and nutrients to gastric arterial embolization. It offers objective and authoritative information for practicing professionals; not only are successful interventions discussed and updated, but cutting-edge and experimental pathways are also anticipated. Obesity is the foremost nutritional challenge worldwide. Its companion is type-2 diabetes, the most prevalent metabolic disease. Together they represent the diabesity epidemic, which is draining resources, overwhelming healthcare facilities, and impacting life expectancy and quality of life everywhere. No country has been spared, and most medical specialties have been affected. Many books focus on the surgical options for obesity and diabetes, namely bariatric and metabolic operations. Information on the clinical and pharmacological treatment is also available, conveyed by standard texts on internal medicine and endocrinology. Yet endoscopic maneuvers and prostheses, cell therapy for diabetes, and other innovative approaches are hard to come by, as conventional texts overlook such therapies. This timely publication bridges the gaps between all different therapeutic options, also covering advances in the conservative, surgical and parasurgical domains. This book will appeal to seasoned specialists, students and healthcare professionals in training alike. Front Matter....Pages i-x The Dual Burden of Obesity and Diabetes: Old Problems Die Hard....Pages 1-10 Cost of Obesity Recurrence....Pages 11-33 Recent Trends in Bariatric and Metabolic Surgery....Pages 35-67 Perspectives of Robotic Bariatric Surgery....Pages 69-87 Sleeve Gastrectomy and Transit Bipartition....Pages 89-110 Surgical Options in Type 2 Diabetes....Pages 111-129 Endoscopic Therapeutic Options for Type 2 Diabetes....Pages 131-142 Ileal Transposition Surgery: Mechanisms of Weight Loss and Diabetes Improvements....Pages 143-152 Left Gastric Artery Embolization to Treat Obesity: Rationale, Technique, Experimental, and Clinical Studies....Pages 153-169 Pharmacologic Approach to Type 2 Diabetes in Obese Patients....Pages 171-202 Peripheral Signals and Food Intake Control....Pages 203-216 Appetite: Inhibiting Properties of Proteins....Pages 217-229 Cell Therapy for Diabetes....Pages 231-255 Stem Cells Derived Insulin-Secreting Cells for Insulin-Dependent Diabetes Mellitus: Exploiting Laboratory Discoveries....Pages 257-282