Nutrition and Cancer Prevention : New Insights Into the Role of Phytochemicals

Recent advances have contributed to our understanding of how a plant-based diet confers many health advantages and how substances from plants may be effective in the prevention of specific cancers. The Ninth Annual Research Conference of the American Institute for Cancer Research has focused on the latest developments in several categories of nutrients of wide contemporary interests. The conference sessions included such topics as the effects of soy, green tea, selenium, wine, grapes, and spices in cancer prevention. This conference was held in Washington, D.C. on September 2nd and 3rd, 1999, and was entitled Nutrition and Cancer Prevention: New Insights Into the Roles of Phytochemicals. The discussion program included a session that was devoted to the current status of herbal products in relation to cancer prevention, in recognition of the increasing attention that complementary and alternative medicine has been receiving from the scientific community as well as the general public. A separate presentation addressed the issue of nutritional supplements and cancer prevention. Front Matter....Pages i-xii Soybeans and Cancer Prevention: A Complex Food and a Complex Disease....Pages 1-10 Dietary Soy Reduces Colon Carcinogenesis in Human and Rats....Pages 11-17 Soy and Risk of Hormone-Related and Other Cancers....Pages 19-28 Role of Tomatoes, Tomato Products and Lycopene in Cancer Prevention....Pages 29-37 Tea and Tea Polyphenols in Cancer Prevention....Pages 39-53 Effects of Tea Polyphenols on the Signal Transduction Pathways....Pages 55-67 Mechanisms by Which Garlic and Allyl Sulfur Compounds Suppress Carcinogen Bioactivation....Pages 69-81 Antiproliferative Effects of Garlic-Derived and Other Allium Related Compounds....Pages 83-106 Considering the Mechanisms of Cancer Prevention by Selenium....Pages 107-117 Selenium Metabolism and Mechanisms of Cancer Prevention....Pages 119-130 Apoptosis and Angiogenesis in Cancer Prevention by Selenium....Pages 131-145 Resveratrol Inhibits The Expression Of Cyclooxygenase-2 In Mammary Epithelial Cells....Pages 147-157 The World of Resveratrol....Pages 159-182 The Effects of Resveratrol on CYP1A1 Expression and Aryl Hydrocarbon Receptor Function In Vitro ....Pages 183-193 Herbals and Cancer....Pages 195-202 The Role of Dietary Supplements in Health....Pages 203-217 The Beta-Carotene Story....Pages 219-231 Dietary Intervention Strategies: Validity, Execution and Interpretation of Outcomes....Pages 233-253 Nutrition and Cancer Prevention: New Insights into the Role of Phytochemicals. Future Directions....Pages 255-262 Chemoprevention: Progress And Opportunity....Pages 263-274 Back Matter....Pages 275-347