Nitric Oxide and Free Radicals in Peripheral Neurotransmission (Nitric Oxide in Biology and Medicine, 2)

"Nitric Oxide and Free Radicals in Peripheral Neurotransmission" is a welcome addition to the literature and describes current research into the role of nitric oxide in the peripheral nervous system and its associated organs. Topics covered range from general consideration of nitrergic transmission, in its broadest sense, to elaboration of our current understanding of the role of nitric oxide in transmission in individual peripheral organs, including its role as a backup, or alternate as well as chief transmitter. The influence of nitric oxide and related compounds on the more conventional modes of autonomic transmission are also considered. Aimed at students and researchers in the areas of neuroscience and physiology, "Nitric Oxide and Free Radicals in Peripheral Neurotransmission" also covers the emerging role of abnormal nitric oxide function in disease states and, where appropriate, as potential avenues of therapy. Front Matter....Pages i-xii On the Origin and Early Evolution of Neuronal Nitric Oxide Signaling: A Comparative Analysis....Pages 1-34 The Nitrergic Transmitter of the Anococcygeus: Lessons and Insights....Pages 35-56 Interactions Between Nitric Oxide and Other NANC Inhibitory Neurotransmitters in the Periphery: Clues from the Endothelium....Pages 57-77 Nitrergic Neurotransmission in the Lower Urinary Tract and Penile Erectile Tissues....Pages 78-113 Nitrergic Neurotransmission in the Enteric Nervous System....Pages 114-137 Nitric Oxide and Peripheral Neurotransmission in the Lung....Pages 138-159 Nitrergic Neurogenic Control of Resistance Blood Vessels....Pages 160-182 Is There Neural Control of Peripheral Resistance Arteries by Nitrergic Nerves?....Pages 183-198 Nitric Oxide, Perivascular Neural Transmission, and Migraine....Pages 199-215 Presynaptic Modulation of Peripheral Nitrergic Neurotransmission....Pages 216-234 Neural Nitric Oxide Synthase and Neutrophil Function....Pages 235-261 Nitric Oxide Toxicity in Neuronal Injury and Degeneration....Pages 262-278 Peroxynitrite and Nitrergic Neural Transmission: Pathophysiological Implications....Pages 279-306 Nitric Oxide, Peripheral Neuropathy, and Diabetes....Pages 307-326 Potential Clinical Impact of Nitric Oxide and Nitric Oxide Inhibitors in the Periphery....Pages 327-348 Back Matter....Pages 349-357