Nicotinic Receptors in the Nervous System (Methods and New Frontiers in Neuroscience)

Nicotine research has been conducted for the better part of a century, but with the discovery of the relationship of nicotinic systems to Alzheimer's disease, the differentiation of nicotinic receptor subtypes, and the development of novel nicotinic ligands, the field of nicotine research has exploded. This book will provide you reference to the latest research methods and findings concerning nicotinic neural systems. Featuring a unique approach, Nicotinic Receptors in the Nervous System provides integrated coverage of cutting-edge research concerning neuronal nicotinic systems relevant to smoking addiction and cognitive dysfunction. By bringing together molecular and neurochemical applications, this book provides the key to understanding function and dysfunction of nicotinic systems and how they are significant for disease, addiction, and the development of novel drug treatments. Within the next several years, it is very promising that clinical research will support the use of nicotinic treatments for addiction, pain, and cognitive and motor dysfunction. Nicotinic Receptors in the Nervous System provides you with the basic mechanistic background for these treatments as well as the functional assessment necessary to determine therapeutic effects. Booknews Although nicotine is widely known to be the addictive ingredient in cigarettes and other tobacco products, some researchers believe that it may have psychotherapeutic uses. Levin (psychiatry and pharmacology, Duke U. Medical Center) presents 15 contributions that explore molecular and neurochemical behavioral applications related to nicotine's effect on the brain. The chapters are organized into sections that successively study nicotine's effects on the molecular, systemic, and behavioral levels. Specific topics include the effects of nicotine on dopaminergic neurotransmission, mouse models to evaluate genetic influences on responses to nicotine, nicotine and cognition in young and aged nonhuman primates, evaluation of pharmacologic treatments for smoking cessation, and nicotine effects on ADHD. Annotation c. Book News, Inc., Portland, OR (booknews.com) Featuring a unique approach, Nicotinic Receptors in the Nervous System provides integrated coverage of research on neuronal nicotinic systems relevant to smoking addiction and cognitive dysfunction. By bringing together molecular and neurochemical applications, the book provides the key to understanding function and dysfunction of nicotinic systems and how they are significant for disease, addiction, and the development of novel drug treatments. The book presents readers with the basic mechanistic background for these treatments as well as the functional assessment necessary to determine therapeutic effects. Nicotine research has been conducted for the better part of a century, but with the discovery of the relationship of nicotinic systems to Alzheimer's disease, the differentiation of nicotinic receptor subtypes, and the development of novel nicotinic ligands, the field of nicotine research has exploded. This book will provide you reference to the latest research methods and findings concerning nicotinic neural systems. Featuring a unique approach, Nicotinic Receptors in the Nervous System provides integrated coverage of cutting-edge research concerning neuronal nicotinic systems relevant Presents research on neuronal nicotinic systems relevant to smoking addiction and cognitive dysfunction. The text includes reviews of nicotine research on molecular, neurochemical, translational, and clinical levels of analysis, and discusses the application of this knowledge to diseases