Neutron Scattering in Biology: Techniques and Applications (Biological and Medical Physics, Biomedical Engineering) (Biological and Medical Physics, Biomedical Engineering)

The advent of new neutron facilities and the improvement of existing sources and instruments world wide supply the biological community with many new opportunities in the areas of structural biology and biological physics. The present volume offers a clear description of the various neutron-scattering techniques currently being used to answer biologically relevant questions. Their utility is illustrated through examples by some of the leading researchers in the field of neutron scattering. This volume will be a reference for researchers and a step-by-step guide for young scientists entering the field and the advanced graduate student.Появление новых нейтронных возможностей и усовершенствование существующих источников, и инструментов по всему миру дают новые начала в областях структурной биологии и биологической физики. Предлагается описание различных методов рассеивания нейтронов. Вся полезность проиллюстрирована примерами ведущих исследователей в области нейтронного рассеивания. Эта книга подходит для исследователей, молодых ученых,студентов и аспирантов, занимающихся по этим направлениям.Доп. информация ## Contents \* Neutron Scattering for Biology T.A. Harroun, G.D. Wignall, J. KatsarasPart I Elastic Techniques \* Single Crystal Neutron Diffraction and Protein Crystallography, C.C. Wilson, D.A. Myles \* Neutron Protein Crystallography: Hydrogen and Hydration in Proteins,N. Niimura \* Neutron Protein Crystallography: Technical Aspects and Some Case Studies at Current Capabilities and Beyond, M. Blakeley, A.J.K. Gilboa, J. Habash, J.R. Helliwell, D. Myles, J. Raftery \* Detergent Binding in Membrane Protein Crystals by Neutron Crystallography, P. Timmins \* High-Angle Neutron Fiber Diffraction in the Study of Biological Systems, V.T. Forsyth, I.M. Parrot \* Neutron Scattering from Biomaterials in Complex Sample Environments, J. Katsaras, T.A. Harroun, M.P. Nieh, M. Chakrapani, M.J. Watson, V.A. Raghunathan \* Small-Angle Neutron Scattering from Biological Molecules, J.K. Krueger, G.D. Wignall . \* Small Angle Neutron Scattering from Proteins, Nucleic Acids, and Viruses, S. Krueger, U.A. Perez-Salas, S.K. Gregurick, D. Kuzmanovic \* Structure and Kinetics of Proteins Observed by Small Angle Neutron Scattering, M.W. Roessle, R.P. May \* Complex Biological Structures: Collagen and Bone, P. Fratzl, O. Paris \* Structural Investigations of Membranes in Biology by Neutron Reflectometry, C.F. Majkrzak, N.F. Berk, S. Krueger, U.A. Perez-Salas Protein Adsorption and Interactions at Interfaces, J.R. Lu \* Complex Biomimetic Structures at Fluid Surfaces and Solid-Liquid Interfaces, T. Gutberlet, M. LЂoschePart II Inelastic Techniques \* Quasielastic Neutron Scattering in Biology, R.E. Lechner, S. Longeville . \* Quasielastic Neutron Scattering in Biology, Part II: Applications, R.E. Lechner, S. Longeville . \* Conformational Dynamics Measured with Proteins in Solution, J. Fitter . \* Relating Protein Dynamics to Function and Structure: The Purple Membrane, U. Lehnert, M. Weik \* Biomolecular Spectroscopy Using Pulsed-Source Instruments, H.D. Middendorf \* Brownian Oscillator Analysis of Molecular Motions in Biomolecules, W. Doster . \* Internal Dynamics of Proteins and DNA: Analogy to Glass-Forming Systems, A.P. Sokolov, R.B. Gregory . \* Structure and Dynamics of Model Membrane Systems Probed by Elastic and Inelastic Neutron Scattering, T. Salditt, M.C. RheinstЂadter \* Subnanosecond Dynamics of Proteins in Solution: MD Simulations and Inelastic Neutron Scattering, M. Tarek, D.J. Tobias ## Примеры страниц [скриншоты] Neutron Scattering for Biology....Pages 1-18 Front Matter....Pages 19-19 Single Crystal Neutron Diffraction and Protein Crystallography....Pages 21-42 Neutron Protein Crystallography: Hydrogen and Hydration in Proteins....Pages 43-62 Neutron Protein Crystallography: Technical Aspects and Some Case Studies at Current Capabilities and Beyond....Pages 63-72 Detergent Binding in Membrane Protein Crystals by Neutron Crystallography....Pages 73-83 High-Angle Neutron Fiber Diffraction in the Study of Biological Systems....Pages 85-105 Neutron Scattering from Biomaterials in Complex Sample Environments....Pages 107-126 Small-Angle Neutron Scattering from Biological Molecules....Pages 127-160 Small Angle Neutron Scattering from Proteins, Nucleic Acids, and Viruses....Pages 161-185 Structure and Kinetics of Proteins Observed by Small Angle Neutron Scattering....Pages 187-204 Complex Biological Structures: Collagen and Bone....Pages 205-223 Structural Investigations of Membranes in Biology by Neutron Reflectometry....Pages 225-263 Protein Adsorption and Interactions at Interfaces....Pages 265-282 Complex Biomimetic Structures at Fluid Surfaces and Solid-Liquid Interfaces....Pages 283-306 Front Matter....Pages 307-307 Quasielastic Neutron Scattering in Biology, Part I: Methods....Pages 309-354 Quasielastic Neutron Scattering in Biology, Part II: Applications....Pages 355-397 Conformational Dynamics Measured with Proteins in Solution....Pages 399-418 Relating Protein Dynamics to Function and Structure: The Purple Membrane....Pages 419-434 Biomolecular Spectroscopy Using Pulsed-Source Instruments....Pages 435-460 Brownian Oscillator Analysis of Molecular Motions in Biomolecules....Pages 461-483 Front Matter....Pages 307-307 Internal Dynamics of Proteins and DNA: Analogy to Glass-Forming Systems....Pages 485-502 Structure and Dynamics of Model Membrane Systems Probed by Elastic and Inelastic Neutron Scattering....Pages 503-530 Subnanosecond Dynamics of Proteins in Solution: MD Simulations and Inelastic Neutron Scattering....Pages 531-548

the Advent Of New Neutron Facilities And The Improvement Of Existing Sources And Instruments World Wide Supply The Biological Community With Many New Opportunities In The Areas Of Structural Biology And Biological Physics. The Present Volume Offers A Clear Description Of The Various Neutron-scattering Techniques Currently Being Used To Answer Biologically Relevant Questions. Their Utility Is Illustrated Through Examples By Some Of The Leading Researchers In The Field Of Neutron Scattering. This Volume Will Be A Reference For Researchers And A Step-by-step Guide For Young Scientists Entering The Field And The Advanced Graduate Student.

Annotation The advent of new neutron facilities and the improvement of existing sources and instruments world wide offers the biological community with many new opportunities in the areas of structural biology and biological physics. The present volume offers a clear description of the various neutron-scattering techniques currently being used to answer biologically relevant questions. Their utility is illustrated through examples by some of the leading researchers in the field of neutron scattering. This volume will be a reference for each researcher and a step-by-step guide for the youngnbsp;scientist or advanced graduate student