Neurotoxicity of Nanomaterials and Nanomedicine

__Neurotoxicity of Nanomaterials and Nanomedicine__ presents an overview of the exciting research in neurotoxicity and nanomaterials. Nanomaterials have been extensively used in medicine, including diagnosis probes, drug carriers, and embedded materials. While some have been approved for clinical use, most nanomaterials are waiting to be transferred from lab to clinic. However, the toxicity is a main barrier that restricts the translation. This comprehensive book includes chapters on the most commonly used individual nanoparticles, with information on the applications, neurotoxicity, and related mechanisms of each, providing the most in-depth and current information available. The book examines the pathways that nanomaterials enter into, and eliminate, from the brain, along with the strategies that could reduce the neurotoxicity of nanomaterials. Providing a background to the subject, detailed information, and ideas for future directions in research, the book is essential for students and researchers in toxicology, and for those in medicine, neurology, pharmacology, pharmaceutical science, and materials science who are researching nanomaterials. * Presents a thorough discussion of the most common nanoparticles in the brain and their neurotoxicology * Includes the most common nanoparticles, their applications, and mechanisms * Provides one of the first books to focus on nanomedicine and neurotoxicity Content: Front Matter,Copyright,List of Contributors,Biography,Preface,Introduction and OverviewEntitled to full textChapter 1 - The Medical Applications of Nanomaterials in the Central Nervous System, Pages 1-31, H. Gao, X. Jiang Chapter 2 - The Route of Nanomaterials Entering Brain, Pages 33-57, Y. Liu, Q. He Chapter 3 - The Distribution and Elimination of Nanomaterials in Brain, Pages 59-74, X. Gao, X. Gu, H. Chen Chapter 4 - Current Perspective on Nanomaterial-Induced Adverse Effects: Neurotoxicity as a Case Example, Pages 75-98, J. Li, F.L. Martin Chapter 5 - Toxicity of Titanium Dioxide Nanoparticles on Brain, Pages 99-125, L.Q. Shao, B. Song Chapter 6 - The Application, Neurotoxicity, and Related Mechanism of Iron Oxide Nanoparticles, Pages 127-150, G. Kiliç, N. Fernández-Bertólez, C. Costa, F. Brandão, J.P. Teixeira, E. Pásaro, B. Laffon, V. Valdiglesias Chapter 7 - The Application, Neurotoxicity, and Related Mechanisms of Silver Nanoparticles, Pages 151-177, L. Strużyńska Chapter 8 - The Applications, Neurotoxicity, and Related Mechanism of Gold Nanoparticles, Pages 179-203, S.J.S. Flora Chapter 9 - The Applications, Neurotoxicity, and Related Mechanisms of Manganese-Containing Nanoparticles, Pages 205-225, K. Ikeda, T. Tachibana, Y. Manome Chapter 10 - The Application, Neurotoxicity, and Related Mechanism of Silica Nanoparticles, Pages 227-257, C. Zhong, M. He, K. Lou, F. Gao Chapter 11 - The Synthesis, Application, and Related Neurotoxicity of Carbon Nanotubes, Pages 259-284, D. Shi, G. Mi, T.J. Webster Chapter 12 - The Application, Neurotoxicity, and Related Mechanism of Cationic Polymers∗, Pages 285-329, Y. Li, D. Ju Chapter 13 - Perspective on Strategies to Reduce the Neurotoxicity of Nanomaterials and Nanomedicines, Pages 331-336, H. Gao, X. Jiang Index, Pages 337-343

Neurotoxicity of Nanomaterials and Nanomedicine presents an overview of the exciting research in neurotoxicity and nanomaterials. Nanomaterials have been extensively used in medicine, including diagnosis probes, drug carriers, and embedded materials. While some have been approved for clinical use, most nanomaterials are waiting to be transferred from lab to clinic. However, the toxicity is a main barrier that restricts the translation.

This comprehensive book includes chapters on the most commonly used individual nanoparticles, with information on the applications, neurotoxicity, and related mechanisms of each, providing the most in-depth and current information available. The book examines the pathways that nanomaterials enter into, and eliminate, from the brain, along with the strategies that could reduce the neurotoxicity of nanomaterials.

Providing a background to the subject, detailed information, and ideas for future directions in research, the book is essential for students and researchers in toxicology, and for those in medicine, neurology, pharmacology, pharmaceutical science, and materials science who are researching nanomaterials.

• Presents a thorough discussion of the most common nanoparticles in the brain and their neurotoxicology
• Includes the most common nanoparticles, their applications, and mechanisms
• Provides one of the first books to focus on nanomedicine and neurotoxicity

Neurotoxicity Of Nanomaterials And Nanomedicine Presents An Overview Of The Exciting Research In Neurotoxicity And Nanomaterials. Nanomaterials Have Been Extensively Used In Medicine, Including Diagnosis Probes, Drug Carriers, And Embedded Materials. While Some Have Been Approved For Clinical Use, Most Nanomaterials Are Waiting To Be Transferred From Lab To Clinic. However, The Toxicity Is A Main Barrier That Restricts The Translation. This Comprehensive Book Includes Chapters On The Most Commonly Used Individual Nanoparticles, With Information On The Applications, Neurotoxicity, And Related Mechanisms Of Each, Providing The Most In-depth And Current Information Available. The Book Examines The Pathways That Nanomaterials Enter Into, And Eliminate, From The Brain, Along With The Strategies That Could Reduce The Neurotoxicity Of Nanomaterials. Providing A Background To The Subject, Detailed Information, And Ideas For Future Directions In Research, The Book Is Essential For Students And Researchers In Toxicology, And For Those In Medicine, Neurology, Pharmacology, Pharmaceutical Science, And Materials Science Who Are Researching Nanomaterials. Edited By Xinguo Jiang, Huile Gao. Includes Bibliographical References And Index. Mode Of Access: World Wide Web.