پاتولوژی عصبی اعتیاد به مواد و سوءمصرف مواد. جلد سوم، فرآیندها و مکانیسم‌های عمومی، داروهای تجویزی، کافئین و آریکا، سوءمصرف چنددارویی، اعتیادهای نوظهور و اعتیادهای غیر دارویی

"This volume shows that the neuropathological features of one addiction are often applicable to those of others. It details how a further understanding of these commonalties can provide a platform for the study of specific addictions in greater depth, all in an effort to create new modes of understanding, causation, prevention, and treatment" -- OCLC.;"Neuropathology of Drug Addictions and Substance Misuse, Volume 2: Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants and International Aspects is the second of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. Each volume serves to update the reader's knowledge on the broader field of addiction as well as to deepen understanding of specific addictive substances. Volume 2 addresses stimulants, club and dissociative drugs, hallucinogens, and inhalants and solvents. Each section provides data on the general, molecular and cellular, and structural and functional neurological aspects of a given substance, with a focus on the adverse consequences of addictions. Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention, and treatment. However, marshalling data on the complex relationships between addictions is difficult due to the myriad material and substances" -- OCLC.;"Neuropathology of Drug Addictions and Substance Misuse, Volume 3: General Processes and Mechanisms, Prescription Medications, Caffeine and Areca, Polydrug Misuse, Emerging Addictions and Non-Drug Addictions "is the third of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. Each volume serves to update the reader s knowledge on the broader field of addiction as well as to deepen understanding of specific addictive substances. "Volume 3" addresses prescription medications, caffeine, polydrug misuse, and non-drug addictions. Each section provides data on the general, molecular, cellular, structural, and functional neurological aspects of a given substance, with a focus on the adverse consequences of addictions. Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention and treatment. However, marshalling data on the complex relationships between addictions is difficult due to the myriad of material and substances. Offers a modern approach to understanding the pathology of substances of abuse, offering an evidence-based ethos for understanding the neurology of addictionsFills an existing gap in the literature by serving as a one-stop-shopping synopsis of everything to do with the neuropathology of drugs of addiction and substance misuseIncludes in each chapter: list of abbreviations, abstract, introduction, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, full referencesOffers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and from the genome to whole body." -- OCLC. Content: Front Matter,Copyright,List of Contributors,Preface,AcknowledgmentsEntitled to full textPart I: Principles of Addictions, Overviews, Detailed Processes and MechanismsSection A: General AspectsChapter 1 - Drugs and the Human Envirome, Pages 5-16, James C. Anthony Chapter 2 - Psychoactive Plants Used during Religious Rituals, Pages 17-28, H. Umit Sayin Chapter 3 - Substance Use Disorders and Comorbid Mental Illness: A Focus on Epidemiological Data Regarding Mood and Anxiety Disorders, Pages 29-39, Shaul Lev-Ran, Daniel Feingold, Jonah Fox Chapter 4 - Mephedrone and Mephedrone-Based Cocktails: Market, Analysis, Mechanisms of Action, and Toxicity, Pages 40-49, Francesco S. Romolo, Paola A. Fiore, Edoardo Bottoni, Simone Cappelletti, Mariarosaria Aromatario, Costantino Ciallella Chapter 5 - Substance-Induced Psychosis: Conceptual and Diagnostic Challenges in Clinical Practice, Pages 50-57, Melissa A. Weibell, Wenche ten Velden Hegelstad, Jan Olav Johannessen Chapter 6 - Sleep and Drug Addiction, Pages 58-67, Laís F. Berro, Leonard L. Howell, Sergio Tufik, Monica L. Andersen Chapter 7 - Hypothalamic and Midbrain Cells, Tyrosine Hydroxylase, and Implications for Drug Addiction, Pages 71-81, Grażyna Jerzemowska Chapter 8 - Oxytocin: Providing New Avenues for Treating and Understanding Problematic Drug Use, Pages 82-92, Michael T. Bowen, Jiajun Liu, Femke T.A. Buisman-Pijlman Chapter 9 - Role of D2-like Heteroreceptor Complexes in the Effects of Cocaine, Morphine, and Hallucinogens, Pages 93-101, Dasiel O. Borroto-Escuela, Karolina Wydra, Luca Ferraro, Alicia Rivera, Malgorzata Filip, Kjell Fuxe Chapter 10 - Glutamate Receptors and Drug Addiction, Pages 102-110, M. Foster Olive Chapter 11 - Effect of Interacting Nonsteroidal Anti-Inflammatory Agents (NSAIDs) and Opioids on Mood: Pharmacodynamic Considerations in Misuse and Abuse, Pages 111-119, Mirko Manchia, Martina Pinna, Eileen M. Denovan-Wright Chapter 12 - A Mini-Review on Different Commonly Used Abusive Drugs and the Interactions of These Drugs and Chinese Herbs, Pages 120-128, Yemina Chung, Andrew W.S. Yong, Willmann Liang, Hong Chai Tang, Maria S.M. Wai, David T. Yew Chapter 13 - Interaction of Drugs of Addiction with DNA, Pages 129-136, Ali A. Ensafi, Esmaeil Heydari-Bafrooei Chapter 14 - Drugs of Abuse and DNA Methylation in the Brain: Ethanol, Cocaine, Amphetamine–Methamphetamine, Heroin, Antidepressants, and Antipsychotics, Pages 137-143, Domniki Fragou, Leda Kovatsi Chapter 15 - Orexin/Hypocretin System and Drug Addiction, Pages 144-152, Alessandra Matzeu, Rémi Martin-Fardon Chapter 16 - Reverse Translational Implications of Genome-Wide Association Studies for Addiction Genetics, Pages 153-164, F. Scott Hall Chapter 17 - Polymorphisms in the Delta Opioid Receptor Gene (OPRD1) and Drug Addiction: Candidate Genes, Transgenic Mouse Models, and Genome-Wide Association Studies, Pages 165-175, Florence F. Roussotte, Paul M. Thompson Chapter 18 - Drug Addictions and Genetics of the Dopamine Pathway, Pages 176-182, Yann Le Strat, Nicolas Ramoz, Philip Gorwood Chapter 19 - In Silico Chemogenomics Knowledgebase and Computational System Neuropharmacology Approach for Cannabinoid Drug Research, Pages 183-195, Xiang-Qun Xie, Lirong Wang, Junmei Wang, Zhaojun Xie, Peng Yang, Qin Ouyang Chapter 20 - Cocaine- and Amphetamine-Regulated Transcript (CART) Peptide and Drug Addiction, Pages 196-205, Martin O. Job Chapter 21 - The Cerebellar Landscape of Drug Addiction, Pages 209-218, Marta Miquel, Dolores Vazquez-Sanroman, María Carbo-Gas, Isis Gil-Miravet, Carla Sanchis-Segura Chapter 22 - Movement Dysfunction as a Neuropathology of Illicit Stimulant Abuse, Pages 219-228, Verity Pearson-Dennett, Robert A. Wilcox, Jason M. White, Gabrielle Todd Chapter 23 - Left Hemispheric “Imbalance” in Drug Addiction, Pages 229-238, Michela Balconi, Roberta Finocchiaro Chapter 24 - Co-occurence of Substance Use and Personality Disorders: Epidemiology, Etiopathogenesis, and Treatment, Pages 239-248, Paola Casadio, Deanna Olivoni, Roberta Bonafede, Anna Rita Atti Chapter 25 - Neonatal Abstinence Syndrome: Pharmacological Aspects, Pages 249-257, Kathleen Kopcza, Rachana Singh Chapter 26 - Comorbidity between Substance Use Disorder and Severe Mental Illness: Dual Diagnosis, Pages 258-268, Ana Adan, Irina Benaiges Chapter 27 - Lormetazepam Addiction, Pages 273-282, Lara Magro, Marco Faccini, Roberto Leone Chapter 28 - Prescribing and Dispensing of Benzodiazepines: Implications for Dependence and Misuse, Pages 283-292, M. Mofizul Islam, Suzanne Nielsen, Ian S. McRae, Paul S. Haber, Apo Demirkol, Bridin Murnion, Hester Wilson, Katherine M. Conigrave Chapter 29 - Bidirectional Plasticity of Hippocampal Glutamate Receptors Is Central to Expression of Benzodiazepine Withdrawal-Anxiety, Pages 295-307, Elizabeth I. Tietz Chapter 30 - Effect of Chronic Benzodiazepine Exposure on GABAA Receptors: Regulation of GABA/Benzodiazepine Site Interactions, Pages 308-316, María Clara Gravielle Chapter 31 - The K+-Cl− Cotransporter KCC2 and Zolpidem, Pages 317-324, Masahiro Shibasaki, Tomohisa Mori, Tsutomu Suzuki Chapter 32 - Benzodiazepine Misuse and Addiction. Risk Factors and Adverse Behavioral Aspects, Pages 327-333, Anna Konopka, Justyna Pełka Wysiecka, J. Samochowiec Chapter 33 - Benzodiazepines, Age-Related Pharmacological Changes, and Risk of Falls in Older Adults, Pages 334-344, Anna Lukačišinová Ballóková, Daniela Fialová Chapter 34 - The Substantia Nigra Pars Reticulata in Sedative-Hypnotic Withdrawal, Pages 345-355, Lauren C. Kruse, Kari J. Buck Chapter 35 - Assays for Benzodiazepines, Pages 359-370, Elisabetta Bertol, Fabio Vaiano Chapter 36 - Weak Opioid Analgesics Abuse and Addiction: A Comparison of the Pharmacology and Pharmacoepidemiology of Codeine, Dihydrocodeine, and Tramadol, Pages 375-391, Anne Roussin, Aurore Palmaro, Maryse Lapeyre-Mestre Chapter 37 - Maternal Codeine and Its Effect on the Fetus and Neonate: A Focus on Pharmacogenomics, Neuropathology, and Withdrawal, Pages 392-398, Amuchou Singh Soraisham Chapter 38 - Methadone Usage, Misuse, and Addiction Processes: An Overview, Pages 399-406, Zia Li, Zheng-Xiong Xi Chapter 39 - Tramadol, Usage, Misuse, and Addiction Processes, Pages 407-416, Behjat Sheikholeslami, Bardia Jamali, Mohammadreza Rouini Chapter 40 - Tramadol Abuse in the Elderly, Pages 417-422, Ebru Findikli, Hatice Altun Chapter 41 - Oligodendrocyte Responses, Myelination, and Opioid Addiction Treatments, Pages 425-432, Carmen Sato-Bigbee, Susan E. Robinson Chapter 42 - Opioids and TRPV1 Receptors, Pages 433-442, Ali Roohbakhsh, Ali Shamsizadeh Chapter 43 - Opioids and Serotonin Syndrome: An Example with Tramadol, Pages 443-448, Brian A. Falls Chapter 44 - Opioid Dependence and the Adenylyl Cyclase/cAMP Signaling, Pages 449-456, Hai-Yu Yang, Bhushan Vijay Nagpure, Jin-Song Bian Chapter 45 - Central Nervous System Penetration of the Opioid Oxycodone, Pages 457-466, Hannu Kokki, Merja Kokki Chapter 46 - Opioid Modulation of Voltage-Gated Calcium Currents, Pages 467-475, Enrique Soto, Emmanuel Seseña, Rosario Vega Chapter 47 - The Neonatal Brain and Opioids, Pages 476-481, Preeta George, Robert Moore Chapter 48 - Contribution of Spinal Cord mTORC1 to Chronic Opioid Tolerance and Hyperalgesia, Pages 482-489, Linlin Sun, Brianna M. Lutz, Yuan-Xiang Tao Chapter 49 - Interaction of Codeine with DNA, Pages 490-496, Ali A. Ensafi, Maryam Amini, Esmaeil Heydari-Bafrooei Chapter 50 - Fentanyl and Its Impact on Cell Functions, Pages 497-507, Kiichi Hirota Chapter 51 - Morphine and Trafficking of a Mu Opioid Receptor Interacting Protein WLS, Pages 508-516, Beverly A.S. Reyes, Wade H. Berrettini, Nicole M. Enman, Elisabeth J. Van Bockstaele Chapter 52 - Fas, Bcl-2, and Caspase-3 Protein and Morphine Addiction, Pages 517-524, Liwei Liu, Jingsheng Lou, Qiang Fu Chapter 53 - An Overview on Methadone-Intoxicated Patients, Pages 525-531, Hossein Hassanian-Moghaddam, Nasim Zamani Chapter 54 - Genetic Polymorphisms on OPRM1 Involved in Multiple Responses of a Methadone Maintenance Population: Relationships with Insomnia, Libido, Smoking, and Chemokines, Pages 532-541, Yu-Li Liu, Jieh-Hen Tsung, Chiu-Ping Fang, Sheng-Wen Liu, Chien-Wen Lai, Chieh-Liang Huang, Sheng-Chang Wang Chapter 55 - Modulation of Opioid Analgesic Reward by Inflammatory Agents, Pages 545-554, Kristen A. Hymel, Jason J. Paris, Jay P. McLaughlin Chapter 56 - Suicidal Behavior and Prescription Opioid Medication, Pages 555-566, Veronica B. Searles Quick, Jonathan M. Davis Chapter 57 - Codeine and Psychomotor Activity, Pages 567-576, Marie-Laure Bocca Chapter 58 - Neurobehavior of Neonates Born to Mothers Receiving Opioid Maintenance Treatment: Methadone and Buprenorphine, Pages 577-588, Trecia A. Wouldes Chapter 59 - Prenatal Methadone and Behavioral Sensitization Induced by Methamphetamine, Pages 589-594, Lir-Wan Fan, Lu-Tai Tien Chapter 60 - Treatments for Opioid Dependence and Methadone: Neurological and Behavioral Aspects, Pages 595-602, M.T. Bobes-Bascarán, M.T. Bascarán, S. Al-Halabí, P.A. Saiz, M. Bousoño, M.P. García-Portilla, J. Bobes Chapter 61 - Cognitive Functioning in Methadone Use, Pages 603-607, Michael Soyka Chapter 62 - Sleep Disturbances in Methadone Maintenance Treatment (MMT) Patients, Pages 608-615, Nan-Ying Chiu, Wen-Yu Hsu Chapter 63 - The Neuropathology of Drug Addictions and Substance Misuse: Assays for Fentanyl, Pages 619-630, Koichi Inoue, Motoo Nomura Chapter 64 - Assays for Tramadol and Its Metabolites, Pages 631-645, Behjat Sheikholeslami, Meshkat Torkamanian, Yalda Hosseinzadeh Ardakani, Bardia Jamali, Mohammadreza Rouini Chapter 65 - Methylphenidate Abuse: An Overview, Pages 651-659, Maximilian Gahr, Paul L. Plener Chapter 66 - The Impact of Methylphenidate on Circadian Rhythms and Clock Gene Expression, Pages 663-672, Andrew N. Coogan, Johannes Thome, Alison L. Baird Chapter 67 - The Characteristics of Acute and Chronic Methylphenidate, Dose, and Route on Female and Male Animal Behavior, Pages 675-681, Nachum Dafny Chapter 68 - Methylphenidate and Cognitive Performance, Pages 682-691, Eldad Yechiam, Nirit Agay Chapter 69 - Methylphenidate and Suicide, Pages 692-698, Priti Arun, Subhash Das Chapter 70 - The Effect of Methylphenidate on the Ventral Tegmental Area in Adolescent and Adult Animals, Pages 699-706, Natasha Kharas, Nachum Dafny Chapter 71 - Dextromethorphan and Dextrorphan as Heuristic Rapid-Acting, Conventional, and Treatment-Resistant Antidepressants, with Substance Abuse Considerations, Pages 707-717, Edward C. Lauterbach, Samuel D. Shillcutt, Daniel E. Phillips Chapter 72 - Caffeine and Taurine and Energy Drink Abuse, Pages 723-732, Rocco S. Calabrò, Antonino Naro, Placido Bramanti Chapter 73 - General Aspects of Areca Nut Addiction, Pages 733-737, Ahsana Dar Farooq, Ghulam Abbas Chapter 74 - Caffeine, Adenosine A1 Receptors, and Brain Cortex. Molecular Aspects, Pages 741-752, Antoni Cortés, Verònica Casadó-Anguera, Estefanía Moreno, Vicent Casadó Chapter 75 - Caffeine and the Developing Brain: Molecular and Cellular Effects, Pages 753-761, Anzari Atik, Richard Harding, Robert De Matteo, Mary Tolcos Chapter 76 - Effects of Caffeine and Its Cortical Response Studied by Functional Brain Imaging, Pages 765-774, Zang-Hee Cho, Chang-Ki Kang, Chan-A Park, Young-Bo Kim Chapter 77 - Neurobehavioral Aspects of Caffeine, Pages 775-784, Robert N. Hughes Chapter 78 - Oral and Systemic Health Effects of Compulsive Areca Nut Use, Pages 785-793, Stephen Cox, Mafaz Ullah, Hans Zoellner Chapter 79 - Areca Alkaloids and Schizophrenia, Pages 794-802, Maurizio Coppola, Raffaella Mondola, Francesco Oliva, Rocco Luigi Picci Chapter 80 - Attentional Biases for Betel Nut Cues, Pages 803-812, Ming-Chou Ho, Bin Shen, Meng-Chun Chiu, Ling-Jun Liu, Ren-Hau Li, Tze-Chun Tang Chapter 81 - Quantitative Measurement of Caffeine by Optical Methods, Pages 815-826, Wang Xu, Young-Tae Chang Chapter 82 - Betel Quid Dependence Scale, Pages 827-835, Chen-Yi Lee, Thaddeus A. Herzog, Kelle L. Murphy, Yong-Yuan Chang Chapter 83 - Types of Polydrug Usage, Pages 839-849, Olga Hernández-Serrano, Maria Eugènia Gras, Sílvia Font-Mayolas, Mark J.M. Sullman Chapter 84 - Polypharmacy of Potentially Addictive Medications and the Elderly, Pages 850-859, C. Ineke Neutel, Helen J. Johansen Chapter 85 - New Insight into Alcohol and Nicotine Addiction: Neurobiological Findings and Therapeutical Perspectives, Pages 860-871, Mario Vitali, Gemma Battagliese, Mauro Ceccanti Chapter 86 - Multimodal Magnetic Resonance Neuroimaging and Cognition in Polysubstance Users, Pages 872-883, Dieter J. Meyerhoff Chapter 87 - Neuropathological Studies in Polydrug Abusers, Pages 884-889, Andreas Büttner Chapter 88 - Novel Drugs of Abuse: Cannabinoids, Stimulants, and Hallucinogens, Pages 893-902, Evan S. Herrmann, Patrick S. Johnson, Matthew W. Johnson, Ryan Vandrey Chapter 89 - Kratom (Mitragyna speciosa) Use, Addiction Potential, and Legal Status, Pages 903-911, Dessa Bergen-Cico, Kendra MacClurg Chapter 90 - Methylxanthines and Drug Dependence: Interactions and Toxicity, Pages 912-923, Giulia Costa, Micaela Morelli, Nicola Simola Chapter 91 - The Neuropathology of Movement Disorders in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) and Methcathinone (Ephedrone) Addictions, Pages 924-934, Ainars Stepens, Pille Taba Chapter 92 - 25C-NBOMe as a New Hallucinogen, Pages 935-944, Dariusz Zuba, Piotr Adamowicz, Simon Elliott Chapter 93 - Pregabalin Abuse and Addiction, Pages 945-951, Giovanni Martinotti, Georgios Papazisis, Rita Santacroce, Dimitrios Kouvelas, Eduardo Cinosi, Matteo Lupi, Massimo di Giannantonio Chapter 94 - Internet Gaming Disorder, Pages 955-961, Doug Hyun Han, Gi Jung Hyun, Jeong Ha Park, Perry F. Renshaw Chapter 95 - The Neuropathology of Internet Addiction, Pages 962-971, Sevim Karakaş-Çelik, Tuba Edgunlu, Ömer Şenormanci, Ulaş M. Çamsari Chapter 96 - Workaholism: An Addiction to Work, Pages 972-983, Cecilie Schou Andreassen, Ståle Pallesen Chapter 97 - Exercise Addiction, Pages 984-992, Attila Szabo, Mark D. Griffiths, Zsolt Demetrovics Chapter 98 - Compulsive Buying—Features and Characteristics of Addiction, Pages 993-1007, Aviv Weinstein, Aniko Maraz, Mark D. Griffiths, Michel Lejoyeux, Zsolt Demetrovics Chapter 99 - Food Addiction: Applying Substance Use Disorder Criteria and Characteristics to Identify Instances of Addictive-Like Eating, Pages 1008-1018, Miriam E. Bocarsly Chapter 100 - Bulimia Nervosa as an Addiction, Pages 1019-1027, Natalie A. Hadad, Lori A. Knackstedt Chapter 101 - Gambling Disorders: A Focus on Genetic Aspects, Pages 1028-1038, Rida Hashmi, Daniela S.S. Lobo Index, Pages 1039-1068

Neuropathology of Drug Addictions and Substance Misuse, Volume 3: General Processes and Mechanisms, Prescription Medications, Caffeine and Areca, Polydrug Misuse, Emerging Addictions and Non-Drug Addictions is the third of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. Each volume serves to update the reader’s knowledge on the broader field of addiction as well as to deepen understanding of specific addictive substances. Volume 3 addresses prescription medications, caffeine, polydrug misuse, and non-drug addictions. Each section provides data on the general, molecular, cellular, structural, and functional neurological aspects of a given substance, with a focus on the adverse consequences of addictions.

Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention and treatment. However, marshalling data on the complex relationships between addictions is difficult due to the myriad of material and substances.

• Offers a modern approach to understanding the pathology of substances of abuse, offering an evidence-based ethos for understanding the neurology of addictions
• Fills an existing gap in the literature by serving as a “one-stop-shopping” synopsis of everything to do with the neuropathology of drugs of addiction and substance misuse
• Includes in each chapter: list of abbreviations, abstract, introduction, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, full references
• Offers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and from the genome to whole body

Neuropathology of Drug Addictions and Substance Misuse, Volume 3: General Processes and Mechanisms, Prescription Medications, Caffeine and Areca, Polydrug Misuse, Emerging Addictions and Non-Drug Addictions is the third of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. Each volume serves to update the reader's knowledge on the broader field of addiction as well as to deepen understanding of specific addictive substances. Volume 3 addresses prescription medications, caffeine, polydrug misuse, and non-drug addictions. Each section provides data on the general, molecular, cellular, structural, and functional neurological aspects of a given substance, with a focus on the adverse consequences of addictions. Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention and treatment. However, marshalling data on the complex relationships between addictions is difficult due to the myriad of material and substances. Offers a modern approach to understanding the pathology of substances of abuse, offering an evidence-based ethos for understanding the neurology of addictions Fills an existing gap in the literature by serving as a "one-stop-shopping” synopsis of everything to do with the neuropathology of drugs of addiction and substance misuse Includes in each chapter: list of abbreviations, abstract, introduction, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, full references Offers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and from the genome to whole body Neuropathology of Drug Addictions and Substance Misuse, Volume 2: Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants and International Aspects is the second of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. Each volume serves to update the reader's knowledge on the broader field of addiction as well as to deepen understanding of specific addictive substances. Volume 2 addresses stimulants, club and dissociative drugs, hallucinogens, and inhalants and solvents. Each section provides data on the general, molecular and cellular, and structural and functional neurological aspects of a given substance, with a focus on the adverse consequences of addictions. Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention, and treatment. However, marshalling data on the complex relationships between addictions is difficult due to the myriad material and substances. Offers a modern approach to understanding the pathology of substances of abuse, offering an evidence-based ethos for understanding the neurology of addictions Fills an existing gap in the literature by serving as a "one-stop-shopping” synopsis of everything to do with the neuropathology of drugs of addiction and substance misuse Includes in each chapter: list of abbreviations, abstract, introduction, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, and full references Offers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and from the genome to whole body Neuropathology of Drug Addictions and Substance Misuse, Volume One: Foundations of Understanding, Tobacco, Alcohol, Cannabinoids, Opioids and Emerging Addictions provides the latest research in an area that shows that the neuropathological features of one addiction are often applicable to those of others. The book also details how a further understanding of these commonalties can provide a platform for the study of specific addictions in greater depth, all in an effort to create new modes of understanding, causation, prevention, and treatment. The three volumes in this series address new research and challenges, offering comprehensive coverage on the adverse consequences of the most common drugs of abuse, with each volume serving to update the reader's knowledge on the broader field of addiction, while also deepening our understanding of specific addictive substances. Volume One addresses tobacco, alcohol, cannabinoids, and opioids, with each section providing data on the general, molecular/cellular, and structural/functional neurological aspects of a given substance, along with a focus on the adverse consequences of addictions. Provides a modern approach on the pathology of substances of abuse, offering an evidence based ethos for understanding the neurology of addictions Fills an existing gap in the literature by proving a one-stop-shopping synopsis of everything to do with the neuropathology of drugs of addiction and substance misuse Includes a list of abbreviations, abstracts, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, and full references in each chapter Offers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and the genome to whole body