Neurobiology of Respiration (Advances in Experimental Medicine and Biology Book 788)

Respiration is an area of the medical study that undergoes fast developments. A better understanding of the neural and cellular mechanisms underlying respiratory disorders and lung function is essential for the evidence-based pharmacotherapy and for optimizing the patient care and prophylactic measures to improve the health and quality of life. This comprehensive book is a blend of basic and clinical research. The book is thought to promote the translation of science into clinical practice. The book presents an update on the areas of current research and clinical interest in the neurobiology of the respiratory system. Recent innovations in detection and management of respiratory diseases are described. The book will be a base of reference in the field of respiration for years to come and a source of future research ideas. This book is a required text for respiratory scientists, neuropathologists, and for clinicians searching for ‘bench to bedside’ treatments of lung diseases. Front Matter....Pages i-xii Altered Histone Deacetylase Activity and iNOS Expression in Cells Isolated from Induced Sputum of COPD Patients Treated with Tiotropium....Pages 1-6 Involvement of NF-κB and Muscle Specific E3 Ubiquitin Ligase MuRF1 in Cigarette Smoke-Induced Catabolism in C2 Myotubes....Pages 7-17 Siglec-8 in Induced Sputum of COPD Patients....Pages 19-23 Essential Amino Acid Leucine and Proteasome Inhibitor MG132 Attenuate Cigarette Smoke Induced Catabolism in C2 Myotubes....Pages 25-33 Smoking Denial in Cardiovascular Disease Studies....Pages 35-38 Differential Effects of Kainic Acid Lesions in Medullary Raphe on Cough and Sneeze in Anesthetized Rabbits....Pages 39-45 Detection of Chlamydophila Pneumoniae Antigens in Patients with Chronic Cough....Pages 47-50 Antioxidant Activity of Herbal Polysaccharides and Cough Reflex....Pages 51-57 Cytoglobin and Neuroglobin in the Human Brainstem and Carotid Body....Pages 59-64 Flow Cytometry in the Diagnosis of Influenza....Pages 65-70 Accuracy of Rapid Influenza Detection Test in Diagnosis of Influenza A and B Viruses in Children Less Than 59 Months Old....Pages 71-76 Virological Monitoring of Influenza Activity and Influenza-Like Illness in the Epidemic Season 2011–2012 in Poland....Pages 77-82 Incidence of Chlamydophila Pneumoniae Infection in Children During 2007–2010....Pages 83-87 Clinical Features and Outcomes of Influenza A and B Infections in Children....Pages 89-96 Respiratory Complications in Children Hospitalized with Varicella ....Pages 97-102 Hyponatremia in Children Hospitalized due to Pneumonia....Pages 103-108 In Vitro Sensitivity of Acinetobacter baumannii and Pseudomonas aeruginosa to Carbapenems Among Intensive Care Unit Patients....Pages 109-116 Prevalence of Acute Respiratory Tract Diseases Among Soldiers Deployed for Military Operations in Iraq and Afghanistan....Pages 117-124 In Vitro Susceptibility of Staphylococci and Enterococci to Vancomycin and Teicoplanin....Pages 125-132 Sinusitis in People Living in the Medieval Ages....Pages 133-138 Immunization Coverage Against Capsular Bacteria in Splenectomized Patients....Pages 139-145 Umbilical Cord Blood Gas Content, Postnatal State of Neonates, and Lactation After Caesarean and Natural Childbirth....Pages 147-151 Respiratory Function in Pregnant Women....Pages 153-160 Lung Function in Patients with Gastro-Esophageal Reflux Disease and Respiratory Symptoms....Pages 161-166 Efficacy of Noninvasive Mechanical Ventilation in Obese Patients with Chronic Respiratory Failure....Pages 167-173 Near-Infrared Hemoencephalography for Monitoring Blood Oxygenation in Prefrontal Cortical Areas in Diagnosis and Therapy of Developmental Dyslexia....Pages 175-180 Occlusal Stabilization Splint Therapy in Orofacial Pain and Tension-Type Headache....Pages 181-188 Dynamics of Upper Airways During the Müller Maneuver in Healthy Subjects: A Cine MRI Study....Pages 189-195 EMG Analysis of Human Inspiratory Muscle Resistance to Fatigue During Exercise....Pages 197-205 Assessment of Temporomandibular Joint Disease....Pages 207-211 Spirometry Day: A Means to Enhance Social Knowledge on Respiratory Diseases....Pages 213-219 Lung Function in Divers....Pages 221-227 Influence of Traffic-Related Air Pollutants on Lung Function....Pages 229-235 Fractional Exhaled Nitric Oxide in Clinical Trials: An Overview....Pages 237-245 Real-Time Breath Analysis in Type 2 Diabetes Patients During Cognitive Effort....Pages 247-253 Exhaled Nitric Oxide in Specific Inhalation Challenge....Pages 255-264 Integration of Simulated Multipotential Signals: The Role of Integration Window Width and of the Number of Spikes....Pages 265-272 Functional and Topographic Concordance of Right Atrial Neural Structures Inducing Sinus Tachycardia....Pages 273-282 Occurrence of Disseminated Intravascular Coagulation in 2,3,7,8-Tetrachlorodibenzo-p-Dioxin-Induced Pneumonia in the Rat....Pages 283-292 Implementation of Non-invasive Methods in the Diagnosis of Diisocyanate-Induced Asthma....Pages 293-300 Evaluation of a 4-Steps-1-Day Whole Body Challenge Protocol for the Diagnosis of Occupational Asthma due to Diisocyanates....Pages 301-311 Occupational Allergic Respiratory Diseases in Garbage Workers: Relevance of Molds and Actinomycetes....Pages 313-320 Th1, Th2, Th17, and Regulatory Cytokines in Children with Different Clinical Forms of Allergy....Pages 321-328 Soluble Receptor for Urokinase Plasminogen Activator in Community-Acquired Pneumonia in Children....Pages 329-334 Hypersensitivity Pneumonitis due to Metalworking Fluids: How to Find the Antigens....Pages 335-340 Angiogenic Axis Angiopoietin-1 and Angiopoietin-2/Tie-2 in Non-Small Cell Lung Cancer: A Bronchoalveolar Lavage and Serum Study....Pages 341-348 Cancer Incidence in Pulmonary Vasculitis....Pages 349-353 Influence of Delays in Diagnosis and Treatment on Survival in Small Cell Lung Cancer Patients....Pages 355-362 Familial Idiopathic Pulmonary Fibrosis....Pages 363-367 High Resolution Computed Tomography in 2-Year Follow-Up of Stage I Sarcoidosis....Pages 369-374 Altruistic Aptitude: Age-Dependent Influence of Temperament and Emotional Intelligence....Pages 375-383 Effect of Socio-Economic Status on Quality of Life in People Affected with Respiratory Allergy....Pages 385-392 Exposure to Paracetamol and Antibiotics in Early Life and Elevated Risk of Asthma in Childhood....Pages 393-400 Health Behaviors and Quality of Life Among Patients with Chronic Respiratory Disease....Pages 401-406 Attitudes Toward Euthanasia Among Polish Physicians, Nurses and People Who Have No Professional Experience with the Terminally Ill....Pages 407-412 Death as a Result of Violent Asphyxia in Autopsy Reports....Pages 413-416 Respiratory and Systemic Infections in Children with Severe Aplastic Anemia on Immunosuppressive Therapy....Pages 417-425 Back Matter....Pages 427-436 Respiration is a field of the scientific study that undergoes fast developments. A better understanding of the cellular and neural mechanisms underlying respiratory disorders and lung function is essential for the use of the evidence-based therapy and for optimizing the patient care and prophylactic measures. This book provides a comprehensive update on the basic and clinical respiratory research, and on the detection and management of respiratory pathologies. The molecular signaling lies at the base of the pathophysiology of the respiratory system and therapeutic interventions. The neurobiological studies have just started to unravel the complexities of how the molecular signals are translated into respiratory regulation in health and disease. This book helps translate non-clinical findings into clinical applications. It provides diagnostic tips that help the clinician in qualified decision making and describes novel biomarkers that facilitate diagnosis. The book also tackles the importance of the knowledge of the psychosomatic background of disease in getting the optimal patient outcome. The interventional epidemiological studies included in the book correspond to translational medicine that encompasses the basic and social sciences with the goal to improve the health and quality of life. The chapters presented in the book describe the findings of original studies, which were thoughtfully planned and executed in a controlled manner. The book satisfies a requirement for staying abreast of the latest developments in both scientific and clinical sides of respiratory neurobiology. The book will be an enduring base of reference in the field of respiration for years to come. This book is a required text for respiratory scientists, neuropathologists, and for clinicians searching for 'bench-to-bedside' treatments of respiratory disorders