عصب‌شناسی یادگیری و حافظه، ویرایش دوم

The first edition of Neurobiology of Learning and Memory was published in 1998 to rave reviews. As before, this second edition will discuss anatomy, development, systems, and models though the organization and content is substantially changed reflecting advances in the field. Including information from both animal and human studies, this book represents an up-to-date review of the most important concepts associated with the basic mechanism that support learning and memory, theoretical developments, use of computational models, and application to real world problems. The emphasis of each chapter will be the presentation of cutting-edge research on the topic, the development of a theoretical perspective, and providing an outline that will aid a student in understanding the most important concepts presented in the chapter. *New material covers basal ganglia, cerebellum, prefrontal cortex, and fear conditioning*Additional information available on applied issues (i.e., degenerative disease, aging, and enhancement of memory)*Each chapter includes an outline to assist student understanding of challenging concepts*Four-color illustrations throughout Neurobiology of Learning and Memory, Second Edition investigates memory on multiple levels of analysis - looking at brain regions, systems that modulate memory, and how empirical findings can help answer real world issues. Covering recent research on humans, monkeys, and rats, the book discusses how different systems interact and influence each other, and the tools and techniques by which we can study the neurobiological aspects of learning and memory. Divided into three parts, Part I includes developmental and genetic contributions to memory, including the role of specific genes toward learning, memory formation, and memory storage and retrieval. Additional coverage includes plasticity, the electrophysiology of cellular changes, the role of place cells in the hippocampus and interconnected neural circuits, the use of computational models to understand memory processes, and the influence of hormonal processes on learning and memory. Part II discusses the contribution of neural systems in mediating learning and memory. These chapters cover several neural substrates, including the medial temporal lobe, the frontal lobes, amygdala, basal ganglia, and cerebellum. Multiple approaches and techniques aimed at studying these brain regions are presented, including neuroanatomy, electrophysiology, lesion pharmacology, fMRI, behavior, and cognitive analysis. Part III emphasizes the applications of empirical findings to real world issues. These chapters cover issues of reward and drugs of abuse, the effects of aging on memory, the ability to enhance memory, and the importance of studying neurodegenerative diseases from both the molecular and treatment approaches. Suitable as a textbook for graduate and upper level undergraduate courses in the neurobiology of learning and memory, this book will additionally appeal to researchers and libraries looking for a comprehensive overview of research in this rapidly advancing area The first edition of Neurobiology of Learning and Memory was published in 1998 to rave reviews. As before, this second edition will discuss anatomy, development, systems, and models though the organization and content is substantially changed reflecting advances in the field.

Including information from both animal and human studies, this book represents an up-to-date review of the most important concepts associated with the basic mechanism that support learning and memory, theoretical developments, use of computational models, and application to real world problems.

The emphasis of each chapter will be the presentation of cutting-edge research on the topic, the development of a theoretical perspective, and providing an outline that will aid a student in understanding the most important concepts presented in the chapter.

*New material covers basal ganglia, cerebellum, prefrontal cortex, and fear conditioning
*Additional information available on applied issues (i.e., degenerative disease, aging, and enhancement of memory)
*Each chapter includes an outline to assist student understanding of challenging concepts
*Four-color illustrations throughout Contributors......Page 1 Preface......Page 4 Historical Perspective......Page 6 Developmental Approaches to the Memory Process......Page 59 Genetics in Learning and Memory......Page 104 Gene Expression in Learning and Memory......Page 129 Mnemonic Contributions of Hippocampal Place Cells......Page 154 Computations in Memory Systems in the Brain......Page 189 Modulation of Learning and Memory by Adrenal and Ovarian Hormones......Page 241 Neurobiological Views of Memory......Page 267 The Medial Temporal Lobe and Memory......Page 301 Bootstrapping Your Brain: How Interactions Between the Frontal Cortex and Basal Ganglia May Produce Organized Actions and Lofty Thoughts......Page 334 Role of the Striatum in Learning and Memory......Page 350 Neural Systems Involved in Fear and Anxiety Based on the Fear-Potentiated Startle Test......Page 375 Cerebellar Learning......Page 420 Reward and Drugs of Abuse......Page 450 Memory Changes with Age: Neurobiological Correlates......Page 474 Neurodegenerative Diseases and Memory: A Treatment Approach......Page 510 Enhancement of Learning and Memory Performance: Modality- Spec fie Mechanisms of Action......Page 531 Index......Page 565 The first edition of Neurobiology of Learning and Memory was published in 1998 to rave reviews. As before, this second edition will discuss anatomy, development, systems, and models though the organization and content is substantially changed reflecting advances in the field. Including information from both animal and human studies, this book represents an up-to-date review of the most important concepts associated with the basic mechanism that support learning and memory, theoretical developments, use of computational models, and application to real world problems. The emphasis of each chapter will be the presentation of cutting-edge research on the topic, the development of a theoretical perspective, and providing an outline that will aid a student in understanding the most important concepts presented in the chapter. *New material covers basal ganglia, cerebellum, prefrontal cortex, and fear conditioning *Additional information available on applied issues (i.e., degenerative disease, aging, and enhancement of memory) *Each chapter includes an outline to assist student understanding of challenging concepts *Four-color illustrations throughout Neurobiology of Learning and Memory provides an excellent overview of current information on this fast-growing field of neurobiology. The contents have been structured for use as a course text or as a handy resource for researchers in neuro- and cognitive psychology. It discusses learning and memory from developmental, pharmacological, and psychobiological perspectives, as well as changes in learning and memory with age. Neurobiology of Learning and Memory also includes research on invertebrates and vertebrates, presenting basics in anatomy and development along with computational models. It is written in an easy-to-follow format with summaries at the end of each chapter.

Key Features
* Provides an overview of information on the neurobiology of learning and memory
* Discusses learning and memory from developmental, pharmacological, and psychobiological perspectives, and changes in learning and memory with age
* Includes research on invertebrates and vertebrates
* Gives basics on anatomy and development
* Written for easy comprehension with chapter summaries **Neurobiology of Learning and Memory** provides an excellent overview of current information on this fast-growing field of neurobiology. The contents have been structured for use as a course text or as a handy resource for researchers in neuro- and cognitive psychology. It discusses learning and memory from developmental, pharmacological, and psychobiological perspectives, as well as changes in learning and memory with age. **Neurobiology of Learning and Memory** also includes research on invertebrates and vertebrates, presenting basics in anatomy and development along with computational models. It is written in an easy-to-follow format with summaries at the end of each chapter. Key Features\* Provides an overview of information on the neurobiology of learning and memory\* Discusses learning and memory from developmental, pharmacological, and psychobiological perspectives, and changes in learning and memory with age\* Includes research on invertebrates and vertebrates\* Gives basics on anatomy and development\* Written for easy comprehension with chapter summaries