Neurobiology of Hyperthermia, Volume 162 (Progress in Brain Research) (Progress in Brain Research)

The effects of global warming on human health factors with special regards to our brain function are still not well understood. There is an urgent need to expand our knowledge on the effects of hot environment on our brain functions in healthy and in diseased populations. It is still unclear whether infectious events, traumatic injuries, metabolic diseases, carcinogenic events, cardiovascular and respiratory functions will be adversely affected by the rise in global temperature or whether environmental pollutants, such as nanoparticles entered into our body system will produce more damage at high ambient temperatures. This book aims to answer these questions based on recent research carried out by top experts in the field from the USA (11 chapters), Europe (8) chapters), the Middle East (3 chapters), Asia (2 chapters) and Canada (1).These chapters are written in review style and embedded with the author's new and original data in relation to the current knowledge in the field. The book is highly interesting to the first time readers, beginners and students alike as well as provides in-depth knowledge to the professionals. In addition, prospects for future research and recommendations are clearly indicated in each chapter for future growth of the subject in this highly emerging new discipline. * Describes the importance of brain temperature and hyperthermia in disease processes * Presents research on the first observations on Nanoparticles that worsen the outcome of hyperthermia* Discusses the effects of hyperthermia on the blood-brain and blood-cerebrospinal fluid barriers Content: List of Contributors Pages v-vii Preface Pages ix-xiii Hari Shanker Sharma The onset of fever: new insights into its mechanism Review Article Pages 3-14 Clark M. Blatteis Eicosanoids in non-febrile thermoregulation Review Article Pages 15-25 David M. Aronoff, Andrej A. Romanovsky Exercise and heat stress: cerebral challenges and consequences Review Article Pages 29-43 Lars Nybo Neuropsychological determinants of exercise tolerance in the heat Review Article Pages 45-60 Stephen S. Cheung Thermophysiological responses to hyperthermic drugs: extrapolating from rodent to human Review Article Pages 63-79 Christopher J. Gordon Neuroleptic malignant syndrome and serotonin syndrome Review Article Pages 81-104 Koichi Nisijima, Katsutoshi Shioda, Tatsunori Iwamura Radio frequency electromagnetic fields: mild hyperthermia and safety standards Review Article Pages 107-135 John A. D’Andrea, John M. Ziriax, Eleanor R. Adair The effect of induced hyperthermia on the immune system Review Article Pages 137-152 Annette Dieing, Olaf Ahlers, Bert Hildebrandt, Thoralf Kerner, Ingo Tamm, Kurt Possinger, Peter Wust Cerebral pathophysiology and clinical neurology of hyperthermia in humans Review Article Pages 153-169 Olaf L. Cremer, Cor J. Kalkman Methods to produce hyperthermia-induced brain dysfunction Review Article Pages 173-199 Hari Shanker Sharma Hyperthermia and central nervous system injury Review Article Pages 201-217 W. Dalton Dietrich, Helen M. Bramlett Physiological and pathological brain hyperthermia Review Article Pages 219-243 Eugene A. Kiyatkin Nanoparticles aggravate heat stress induced cognitive deficits, blood–brain barrier disruption, edema formation and brain pathology Review Article Pages 245-273 Hari Shanker Sharma, Aruna Sharma Neuropeptides in hyperthermia Review Article Pages 277-293 Fred Nyberg, Mathias Hallberg Interaction between amino acid neurotransmitters and opioid receptors in hyperthermia-induced brain pathology Review Article Pages 295-317 Hari Shanker Sharma Exertional heat illness and human gene expression Review Article Pages 321-346 Larry A. Sonna, Michael N. Sawka, Craig M. Lilly Cellular mechanisms of neuronal damage from hyperthermia Review Article Pages 347-371 Michael G. White, Luminita E. Luca, Doris Nonner, Osama Saleh, Bingren Hu, Ellen F. Barrett, John N. Barrett Heat acclimation and cross-tolerance against novel stressors: genomic–physiological linkage Review Article Pages 373-392 Michal Horowitz Heat shock protein expression in brain: a protective role spanning intrinsic thermal resistance and defense against neurotropic viruses Review Article Pages 395-415 Matthew A. Buccellato, Thomas Carsillo, Zachary Traylor, Michael Oglesbee Cerebral neurons and glial cell types inducing heat shock protein Hsp70 following heat stress in the rat Review Article Pages 417-431 Alfred Pavlik, Inderjeet S. Aneja Heat shock proteins and the heat shock response during hyperthermia and its modulation by altered physiological conditions Review Article Pages 433-446 Michal Horowitz, Sharon D.M. Robinson Changes in CSF composition during heat stress and fever in conscious rabbits Review Article Pages 449-457 Maria Frosini Blood–cerebrospinal fluid barrier in hyperthermia Review Article Pages 459-478 Hari Shanker Sharma, Conrad Earl Johanson Heat stroke and cytokines Review Article Pages 481-524 Lisa R. Leon Oxidative stress and ischemic injuries in heat stroke Review Article Pages 525-546 Chen-Kuei Chang, Ching-Ping Chang, Shyun-Yeu Liu, Mao-Tsun Lin Subject Index Pages 547-591 The effects of global warming on human health factors with special regards to our brain function are still not well understood. There is an urgent need to expand our knowledge on the effects of hot environment on our brain functions in healthy and in diseased populations. It is still unclear whether infectious events, traumatic injuries, metabolic diseases, carcinogenic events, cardiovascular and respiratory functions will be adversely affected by the rise in global temperature or whether environmental pollutants, such as nanoparticles entered into our body system will produce more damage at high ambient temperatures. This book aims to answer these questions based on recent research carried out by top experts in the field from the USA (11 chapters), Europe (8) chapters), the Middle East (3 chapters), Asia (2 chapters) and Canada (1).
These chapters are written in review style and embedded with the author’s new and original data in relation to the current knowledge in the field. The book is highly interesting to the first time readers, beginners and students alike as well as provides in-depth knowledge to the professionals. In addition, prospects for future research and recommendations are clearly indicated in each chapter for future growth of the subject in this highly emerging new discipline.

* Describes the importance of brain temperature and hyperthermia in disease processes
* Presents research on the first observations on Nanoparticles that worsen the outcome of hyperthermia
* Discusses the effects of hyperthermia on the blood-brain and blood-cerebrospinal fluid barriers The effects of global warming on human health factors with special regards to our brain function are still not well understood. There is an urgent need to expand our knowledge on the effects of hot environment on our brain functions in healthy and in diseased populations. It is still unclear whether infectious events, traumatic injuries, metabolic diseases, carcinogenic events, cardiovascular and respiratory functions will be adversely affected by the rise in global temperature or whether environmental pollutants, such as nanoparticles entered into our body system will produce more damage at high ambient temperatures. This book aims to answer these questions based on recent research carried out by top experts in the field from the USA (11 chapters), Europe (8) chapters), the Middle East (3 chapters), Asia (2 chapters) and Canada (1). These chapters are written in review style and embedded with the author s new and original data in relation to the current knowledge in the field. The book is highly interesting to the first time readers, beginners and students alike as well as provides in-depth knowledge to the professionals. In addition, prospects for future research and recommendations are clearly indicated in each chapter for future growth of the subject in this highly emerging new discipline. * Describes the importance of brain temperature and hyperthermia in disease processes * Presents research on the first observations on Nanoparticles that worsen the outcome of hyperthermia * Discusses the effects of hyperthermia on the blood-brain and blood-cerebrospinal fluid barriers