Neuro-psychopharmacology : proceedings of the Tenth Congress of the Collegium Internationale Neuro-Psychopharmacologicum, Québec, July 4-9, 1976

Content: Front Matter , Page iii Copyright , Page iv CINP COMMITTEES , Pages xxi-xxii ACKNOWLEDGEMENTS , Page xxiii PREFACE , Page xxv , P. Deniker, C. Radouco-Thomas, A. Villeneuve Opening Session , Page xxvii OPENING OF THE CONGRESS , Pages 1-2 , A. VILLENEUVE MOT DE BIENVENU DU DOYEN DE LA FACULTÉ DE MÉDECINE WELCOME OF THE DEAN OF THE FACULTY OF MEDICINE , Pages 3-4 , Y. MORIN OPENING REMARKS , Page 5 , T.A. BAN COMMENTS ON THE SCIENTIFIC PROGRAM OF THE TENTH CONGRESS , Pages 7-9 , C. RADOUCO-THOMAS Presidential Address: CLINICAL PHARMACOLOGY AND BIOLOGICAL PSYCHIATRY , Pages 11-16 , P. DENIKER SUMMARY OF THE SESSION , Pages 19-22 , H.E. LEHMANN THE AGING BRAIN: CURRENT THEORIES AND PSYCHOPHARMACOLOGICAL POSSIBILITIES , Pages 23-31 , S. KANOWSKI ASSESSMENT MODALITIES OF COGNITIVE FUNCTIONS OF THE AGED PATIENT , Pages 33-38 , J. RICHARD CLINICAL ASSESSMENTS IN PSYCHOGERIATRY , Pages 39-42 , W.J. LENNON, J.R. WITTENBORN A SELECTED REVIEW OF ANXIOLYTICS, NEUROLEPTICS AND ANTIDEPRESSANTS IN PSYCHOGERIATRICS , Pages 43-48 , A. RASKIN AGING, HORMONES AND MENTAL FUNCTIONING , Pages 49-57 , L.F. JARVIK, J.N. WILKINS CEREBRAL PROTECTORS IN PSYCHOGERIATRICS , Pages 59-65 , T. LEMPÉRIÈRE THE PHARMACOLOGY OF NOOTROPIC DRUGS: GEROPSYCHIATRIC IMPLICATIONS , Pages 67-72 , C. GIURGEA SOME CLINICAL STUDIES WITH PIRACETAM – A “NOOTROPIC” SUBSTANCE , Pages 73-81 , P. MINDUS SUMMARY OF THE SESSION , Page 85 , P. PICHOT, S.C. GOLDBERG PREVENTION AND TREATMENT OF DEPRESSION IN GENERAL PRACTICE: A Clinical Center as a New Channel , Pages 87-90 , G.B. CASSANO, C. MAGGINI, P. CASTROGIOVANNI, M. MAURI THE EFFECT OF DRUG TREATMENT ON INTERPERSONAL STYLES OF MANIC PATIENTS , Pages 91-96 , J.M. DAVIS, D. JANOWSKY, M.K. EL-YOUSEF VALIDITY PROBLEMS IN PSYCHIATRIC RATING SCALES AS A FUNCTION OF THE SEVERITY OF DISTURBANCE , Pages 97-101 , H. HEIMANN NEW STATISTICAL AND COMPUTER TECHNIQUES TO MEASURE PSYCHOPATHOLOGICAL CHANGES , Pages 103-104,104a,105-108 , J.F. DREYFUS, A. BRODZIAK, P. PICHOT A CRITERION-REFINED MEASURE OF DEPRESSED MOOD , Pages 109-111,113-115 , S. FISHER, R.C. PILLARD, D.M. MCNAIR SUMMARY OF THE SESSION , Pages 119-121 , J.R. WITTENBORN BRIEF REVIEW OF THE WORK OF THE AD HOC COMMITTEE FOR THE CLINICAL ASSESSMENT OF PSYCHOTROPIC MEDICATION , Pages 123-127 , J.R. WITTENBORN EVALUATION OF ANTIANXIETY DRUGS , Pages 129-133 , D. WHEATLEY INTERNATIONAL STANDARDS FOR CONTROLLED CLINICAL TRIALS OF ANTIDEPRESSANTS , Pages 135-138 , O.J. RAFAELSEN STANDARDS FOR THE CLINICAL STUDY OF ANTIPSYCHOTIC SUBSTANCES , Pages 139-144 , H.E. LEHMANN REVUE DES CRITERES NATIONAUX POUR L'ETUDE CLINIQUE DES SUBSTANCES ANTIPSYCHOTIQUES. DISCUSSION , Pages 145-147 , P. PICHOT A REVIEW OF NATIONAL STANDARDS FOR THE CLINICAL STUDY OF TOXIC CONSEQUENCES OF PSYCHOTROPIC MEDICATION , Pages 149-153 , B. MÜLLER-OERLINGHAUSEN SUMMARY OF THE SESSION , Pages 157-158 , F.A. FREYHAN, T.A. BAN INTERNATIONAL TRAINING COURSES IN PSYCHOPHARMACOLOGY FOR TEACHERS IN MEDICAL SCHOOLS , Pages 159-160 , O.J. RAFAELSEN, M. SCHOU TRAINING MODELS IN PSYCHOPHARMACOLOGY: PRESENT ACTIVITIES AND FUTURE PLANS , Pages 161-164 , T.A. BAN, N. SARTORIUS, F.E. VARTANIAN PRECLINICAL PSYCHOPHARMACOLOGY AND THERAPEUTICS: A PHARMACOLOGIST'S POINT OF VIEW , Pages 165-169 , F. SULSER DISCUSSION , Pages 171-172 , C. SANCHEZ TRAINING MODELS IN PSYCHOPHARMACOLOGY: THE PSYCHIATRIST'S POINT OF VIEW , Pages 173-178 , M. LADER DISCUSSION , Pages 179-181 , G.D. BURROWS CLINICAL EXPERIMENTATION AND THERAPEUTIC MODELS , Pages 183-189 , G.B. CASSANO, C. MAGGINI, M. MAURI PROBLEMES DE MISE EN APPLICATION DES MODELES DE FORMATION EN PSYCHOPHARMACOLOGIE , Pages 191-195 , P. PICHOT PROGRAMME OF POST-GRADUATE INSTRUCTION IN THE TREATMENT OF DEPRESSION , Pages 197-199 , P. KIELHOLZ, F.A. FREYHAN SUMMARY OF THE SESSION , Pages 203-204 , P. DENIKER INTRODUCTION , Pages 205-208 , P. DENIKER TESTING PSYCHOSTIMULANTS IN ANIMALS , Pages 209-214 , P. SIMON COMMENTS ON THE REPORT BY P. SIMON , Pages 215-217 , M. FINK PHARMACOKINETICS OF NEW PSYCHOSTIMULANTS. CRITICAL CONSIDERATIONS , Pages 219-224 , P.L. MORSELLI PHYSIOLOGICAL AND ELECTROCLINICAL CORRELATIONS OF SOME NEW PSYCHOSTIMULANT DRUGS , Pages 225-231 , J.C. PECHADRE A CRITICAL STUDY OF THE NEW PSYCHOSTIMULATING DRUGS: CLINICAL ASPECTS , Pages 233-236,236a,237-240 , E. ZARIFIAN SUMMARY OF THE SESSION , Page 243 , H.C.B. DENBER CLINICAL MANAGEMENT OF DRUG DEPENDENCE: PHARMACOTHERAPEUTIC ASPECTS , Pages 245-258 , M.O. MAYKUT RAPID DRUG DETOXIFICATION: FURTHER OBSERVATIONS , Pages 259-262 , H.C.B. DENBER, H. WAGEMAKER BEHAVIOR THERAPIES IN THE TREATMENT OF DRUG DEPENDENCE: METHODOLOGICAL ASPECTS AND BASIC ADVANTAGES AND DISADVANTAGES , Pages 263-272 , W. JANKE ACUPUNCTURE IN NARCOTIC WITHDRAWAL: A PRELIMINARY REPORT ON BIOCHEMICAL CHANGES IN THE BLOOD AND URINE OF HEROIN ADDICTS , Pages 273-280 , H.L. WEN, W.K.K. HO, H.P. FUNG, H.K. WONG, Y.H. NG, H.C. WONG, L. MA EXPERIMENTAL “AURICULAR ELECTRO ACUPUNCTURE” IN MORPHINE-DEPENDENT RATS: BEHAVIORAL AND BIOCHEMICAL OBSERVATIONS , Pages 281-287 , L.K.Y. NG, N.B. THOA, T.C. DOUTHITT, C.A. ALBERT EFFECTIVENESS OF BUTYROPHENONES AND RELATED DRUGS IN NARCOTIC WITHDRAWAL , Pages 289-295 , H. LAL, M.D. HYNES SUMMARY OF THE SESSION , Pages 299-302 , A. VILLENEUVE, D. GINESTET INDIVIDUAL REACTIVITY TO PSYCHOTROPIC DRUGS IN ANIMALS , Pages 303-309 , J.R. BOISSIER, P. SOUBRIÉ, P. SIMON SOME EXAMPLES OF RESISTANCE TO PSYCHOTROPIC DRUGS IN ANIMALS AND MAN , Pages 311-319 , S. GARATTINI ACUTE PHARMACOLOGICAL EFFECTS OF CHLORPROMAZINE IN NEUROLEPTIC THERAPY-RESISTANT CHRONIC SCHIZOPHRENIC PATIENTS , Pages 321-330 , E.F. DOMINO THERAPEUTIC DILEMMA IN NEUROLEPTIC-RESISTANT PSYCHOTIC DISORDERS , Pages 331-338 , A. JUS, A. VILLENEUVE, K. JUS TREATMENT OF THERAPY-RESISTANT AFFECTIVE DISORDERS , Pages 339-342 , P. KIELHOLZ THE ANXIOLYTIC AGENTS AND THEIR LIMITATIONS , Pages 343-350 , K. RICKELS, R.W. DOWNING SUMMARY OF THE SESSION , Pages 355-356 , O.J. RAFAELSEN, Simone RADOUCO-THOMAS THE ROLE OF CALCIUM IN NEUROSECRETION , Pages 357-361 , I.J. KOPIN ROLE OF CATIONS IN THE TRANSPORT MECHANISM OF AMINO ACID PRECURSORS AND NEUROTRANSMITTERS , Pages 363-368 , J. BRUINVELS ACTIVATION OF BRAIN ADENYLATE CYCLASE VIA CA ++ RECEPTORS , Pages 369-373,375-378 , K. VON HUNGEN, S. ROBERTS RELATIONSHIPS BETWEEN CYCLIC NUCLEOTIDES AND DIVALENT CATIONS IN NEUROBLASTOMA CELLS: MODIFICATIONS BY PUTATIVE NEUROTRANSMITTERS AND NEURO-PSYCHOTROPIC DRUGS , Pages 379-381,383-405 , JACQUES HUOT, JACQUELINE PENIT, BERNARD CANTAU, COLETTE GUAY, FRANCE PERRON ALTERATIONS IN HYPOTHALAMIC IONS: INFLUENCE ON LIMBIC FUNCTION , Pages 407-413 , W.L. VEALE, D.L. JONES, K.E. COOPER INTERACTIONS BETWEEN CATIONS AND PSYCHOTROPIC DRUGS , Pages 415-423 , Simone RADOUCO-THOMAS, P. SINGH, Y.K. WANG, S. CHAWLA STUDIES OF SODIUM, MAGNESIUM AND LITHIUM IN PATIENTS WITH AFFECTIVE ILLNESS , Pages 425-432 , T.A. RAMSEY, J. MENDELS, A. FRAZER LITHIUM ACTION ON PHOSPHATE, CALCIUM AND MAGNESIUM , Pages 433-434 , O.J. RAFAELSEN, I.G. KARNIOL, P.K. PLENGE, E.T. MELLERUP SUMMARY OF THE SESSION , Pages 437-438 , A. GUIDOTTI METHODS TO EVALUATE IN VIVO THE ACTIVITY OF GABA RECEPTOR AGONISTS , Pages 439-446 , A. GUIDOTTI THE TURNOVER RATE OF GABA IN BRAIN NUCLEI OF RATS INJECTED WITH DA RECEPTOR ANTAGONISTS AND GABA RECEPTOR AGONISTS , Pages 447-452 , C.C. MAO, A. REVUELTA, E. MARCO, E. COSTA STUDIES ON ENDORPHINS IN MAN , Pages 453-458 , L. TERENIUS, A. WAHLSTRÖM PHARMACOLOGICAL IMPLICATIONS OF DOPAMINERGIC, CHOLINERGIC AND GABAERGIC NEURONS IN THE ACTION OF ANTIPSYCHOTICS AND NARCOTIC ANALGETICS , Pages 459-467 , G. RACAGNI, F. BRUNO, A. MAGGI, F. CATTABENI SODIUM-DEPENDENT HIGH AFFINITY CHOLINE UPTAKE: ITS SIGNIFICANCE AND PRACTICAL USE , Pages 469-475 , M.J. KUHAR, S.F. ATWEH, L.C. MURRIN, J.R. SIMON SUBSTANCE P AND ENKEPHALIN: DISTRIBUTION IN THE NERVOUS SYSTEM AS REVEALED WITH IMMUNOHISTOCHEMISTRY , Pages 477-487 , T. HÖKFELT, R. ELDE, O. JOHANSSON, J-O. KELLERTH, Å LJUNGDAHL, G. NILSSON, B. PERNOW, L. TERENIUS THE EXCITATORY ACTION OF SUBSTANCE P AND TRH ON SPINAL MOTONEURONS , Pages 489-495 , R.A. NICOLL SUMMARY OF THE SESSION , Pages 499-501 , A.G. KARCZMAR HISTOCHEMICAL AND MICROPUNCH ANALYSIS OF AMINERGIC AND CHOLINERGIC PATHWAYS , Pages 503-511,513-515 , D.M. JACOBOWITZ NEUROTRANSMITTERS OF THE HUMAN BRAIN AND THEIR RELATIONSHIPS , Pages 517-525 , T.L. SOURKES NEUROTRANSMITTER ACTIONS AND INTERACTIONS , Pages 527-538 , E. PUIL, K. KRNJEVIC INFLUENCE OF DIFFERENT PUTATIVE NEUROTRANSMITTERS ON ACh RELEASE FROM THE BRAIN AND SPINAL CORD , Pages 539-548 , G. PEPEU, A. NISTRI, P. MANTOVANI EFFECTS OF GABA-ERGIC AND SEROTONINERGIC DRUGS ON THE ACTIVITY OF CHOLINERGIC INTERNEURONS IN RAT STRIATUM , Pages 549-558 , F. JAVOY, C. EUVRARD, J. GLOWINSKI, J. BOCKAERT IMPORTANCE OF INTERACTIONS BETWEEN TRANSMITTER SYSTEMS IN RELATION TO REGULATION OF THE SLEEP–WAKING CYCLE , Pages 559-561,563-568 , J.F. PUJOL, P.E. KEANE, M. JOUVET HUMORAL MECHANISMS UNDERLYING HYPOTHALAMIC AND MESODIENCEPHALIC CONTROL OF APPETITIVE BEHAVIOR AND THERMOREGULATION , Pages 569-579 , R.D. MYERS MULTITRANSMITTER MECHANISMS UNDERLYING SELECTED FUNCTION, PARTICULARLY AGGRESSION, LEARNING AND SEXUAL BEHAVIOR , Pages 581-608 , A.G. KARCZMAR MULTITRANSMITTER MECHANISMS AND TREATMENT OF AFFECTIVE DISEASE , Pages 609-623 , D.J. KUPFER, D.J. EDWARDS SUMMARY OF THE SESSION , Pages 627-628 , J.R. BOISSIER, F. SULSER NOREPINEPHRINE AND SEROTONIN METABOLISM IN THE RAT BRAIN: EFFECTS OF CHRONIC PHENELZINE ADMINISTRATION , Pages 629-640 , I.C. CAMPBELL, R. COLBURN, M.N. WALKER, W. LOVENBERG, D.L. MURPHY NEUROENDOCRINE AND BEHAVIORAL STUDIES WITH FLUOXETINE, AN INHIBITOR OF SEROTONIN UPTAKE IN BRAIN , Pages 641-646 , R.W. FULLER, J.A. CLEMENS, I.H. SLATER, R.C. RATHBUN A PHARMACOTHERAPEUTIC APPROACH TO RESEARCH INTO DEPRESSIVE ILLNESS , Pages 647-653 , B. SHOPSIN ACTION ANTI-DÉPRESSIVE DU L-5-HYDROXYTRYPTOPHANE ET TEST AU PROBÉNÉCIDE , Pages 655-663 , P. PICHOT, C. HAKIM, J.J. MEISCH, J.R. BOISSIER TREATMENT OF INTENTION–ACTION MYOCLONUS BY 5-HYDROXYTRYPTOPHAN , Pages 665-673 , F. LHERMITTE, C.F. DEGOS THE SEROTONERGIC NEUROTRANSMITTER SYSTEM IN THE AFFECTIVE DISORDERS – A PRELIMINARY EVALUATION OF THE ANTIDEPRESSANT AND ANTIMANIC EFFECTS OF FENFLURAMINE , Pages 675-682 , D.L. MURPHY, S. SLATER, C.E. DE LA VEGA, S. LIPPER SUMMARY OF THE SESSION , Pages 685-686 , L.J. POIRIER NEUROPHARMACOLOGY AND HISTOPATHOLOGY OF EXPERIMENTALLY INDUCED PARKINSONISM AND CIRCLING , Pages 687-691,693-696 , L.J. POIRIER, M. FILION, R. MARCHAND, J. DANKOVA SOME ANIMAL MODELS OF EXTRAPYRAMIDAL DISORDERS , Pages 697-702 , N.-E. ANDÉN, B. JOHNELS APORPHINES, SOMATOSTATIN AND PARKINSON'S DISEASE , Pages 703-708 , G.C. COTZIAS, P.S. PAPAVASILIOU, V.L.F. ROSAL DRUG-INDUCED EXTRAPYRAMIDAL REACTIONS: CLINICAL CONSIDERATIONS , Pages 709-713 , A. VILLENEUVE MOTOR ASPECTS OF BASAL GANGLIA DISORDERS: THE EXAMPLE OF PARKINSON'S DISEASE , Pages 715-718 , O. HORNYKIEWICZ EFFECTS OF ANTIPSYCHOTIC DRUGS ON NORMAL AND ABNORMAL ANIMAL BEHAVIOUR , Pages 719-724 , J. ENGEL, S. AHLENIUS CYCLIC NUCLEOTIDES, GABA AND DOPAMINE IN THE MECHANISM OF ACTION OF ANTIPSYCHOTIC DRUGS , Pages 725-730 , M. TRABUCCHI, K. KUMAKURA, P.F. SPANO FOUR DOPAMINE AGONISTS: A CLINICAL CONTINUUM , Pages 731-738 , B. ANGRIST, S. GERSHON CORRELATION BETWEEN CLINICAL EFFECTS OF VARIOUS ANTIDEPRESSANT TREATMENTS AND THEIR EFFECTS ON MONOAMINERGIC RECEPTORS IN THE BRAIN , Pages 739-747 , K. MODIGH AFFECTIVE SYMPTOMS IN DYSTHYROID STATES: POSSIBLE RELATION TO ALTERED SENSITIVITY AT, OR BEYOND CENTRAL CATECHOLAMINE RECEPTORS , Pages 749-754 , T.H. SVENSSON NEW EVIDENCE OF SEROTONIN-DEFICIENT DEPRESSIONS , Pages 755-760 , H.M. VAN PRAAG EXPLORATION OF AFFECTIVE ILLNESS , Pages 761-772 , S. GERSHON, B. SHOPSIN, S. WILK SUMMARY OF THE SESSION , Pages 775-776 , J. MENDLEWICZ, P. MANDEL NEUROCHEMICAL CORRELATES OF BEHAVIOUR AND DRUG RESPONSES GENETICALLY DETERMINED , Pages 777-787 , P. MANDEL, E. KEMPF, A. EBEL, G. MACK PHARMACOGENETIC APPROACH OF THE EFFECT OF MORPHINE AND ALCOHOL IN MICE , Pages 789-797 , Simone RADOUCO-THOMAS, S. JOBIN, F. GARCIN BEHAVIORAL, GENETIC AND NEUROCHEMICAL ASPECTS OF ALCOHOL PREFERENCE OF MICE , Pages 799-816 , A.G. KARCZMAR, C.L. SCUDDER, A.J. KAHN A PHARMACOGENETIC APPROACH TO STUDY LITHIUM TREATMENT IN MANIC-DEPRESSIVE ILLNESS , Pages 817-823 , J. MENDLEWICZ, P. VERBANCK SUMMARY OF THE SESSION , Pages 827-829 , B. GLASSON DRUG DISTRIBUTION IN THE BRAIN , Pages 831-840 , L. MANARA, G. SERRA BRAIN DISTRIBUTION AND PHARMACOKINETICS OF PSYCHOTROPIC DRUGS: DESIPRAMINE , Pages 841-848 , P.D. HRDINA, T.C. DUBAS, E. RIVA METABOLISM AND PHARMACOKINETICS OF A SUBSTITUTED BENZAMIDE SULPIRIDE IN ANIMALS: SPECIFIC LOCALIZATION AND NEURO-ENDOCRINOLOGICAL ASPECT , Pages 849-851,853-857,859-861,863-864 , A. BENAKIS CLINICAL SIGNIFICANCE OF MEASURING PLASMA LEVELS OF PSYCHOTROPIC DRUGS: PHENOTHIAZINES , Pages 865-869 , S.H. CURRY CLINICAL SIGNIFICANCE OF MEASURING PLASMA LEVELS OF ANTIDEPRESSANTS , Pages 871-876 , L.F. GRAM CLINICAL SIGNIFICANCE OF MONITORING PLASMA LEVELS OF BENZODIAZEPINE TRANQUILIZERS AND ANTIEPILEPTIC DRUGS , Pages 877-888 , P.L. MORSELLI PSYCHOPHARMACOLOGICAL CHARACTERIZATION OF ANXIOLYTICS , Pages 891-897 , L. COOK, A.B. DAVIDSON BEHAVIORAL APPROACHES TO STUDY MECHANISMS OF ACTIONS OF MINOR TRANQUILIZERS , Pages 899-906 , P. SOUBRIÉ INTERACTION OF MINOR TRANQUILLIZERS WITH SYNAPTIC PROCESSES MEDIATED BY GABA , Pages 907-916 , W. HAEFELY, H.H. KELLER, L. PIERI, P. POLC, R. SCHAFFNER, R. ZIHLMANN ACTION OF DIAZEPAM, HALOPERIDOL, MORPHINE AND MUSCIMOL ON THE cGMP CONTENT OF CEREBELLUM , Pages 917-924 , A. GUIDOTTI, G. BIGGIO, E. COSTA MODIFICATION OF EXCITATORY AND INHIBITORY SYNAPTIC MECHANISMS BY MINOR TRANQUILIZERS , Pages 925-932 , R.A. NICOLL SUMMARY OF THE SESSION , Pages 934-938 , D. DE WIED, V.G. LONGO MONOAMINERGIC REGULATION OF THE NEUROENDOCRINE TRANSDUCER WHICH CONTROLS ACTH SECRETION , Pages 939-947 , G.R. VAN LOON, R. MASCARDO, A. SHUM, C. KIM, H. DATTA, S. GREEN, J. KIRKLAND, M.J. SOLE, A. KAMBLE STIMULATION OF GROWTH HORMONE AND PROLACTIN RELEASE BY MORPHINE AND OPIATE-LIKE PEPTIDES , Pages 949-960 , F. LABRIE, L. CUSAN, L. FERLAND, A. DUPONT, C.H. LI, D.H. COY, A. ARIMURA, A.V. SCHALLY PSYCHOTROPIC DRUGS AND NEUROENDOCRINE FUNCTION IN PSYCHOPATHOLOGICAL CONDITIONS , Pages 961-969 , P.H. GRUEN, E.J. SACHAR, N. ALTMAN, G. LANGER, F.S. HALPERN PSYCHOTROPIC DRUGS AND SEXUAL BEHAVIOR , Pages 971-980 , B.J. MEYERSON INTERACTION OF PSYCHOTROPIC DRUGS WITH BRAIN OLIGOPEPTIDES , Pages 981-986 , V.G. LONGO, A. SCOTTI DE CAROLIS, A. LOIZZO PITUITARY–ADRENAL SYSTEM HORMONES AND BEHAVIOR , Pages 987-993 , B. BOHUS, D. DE WIED HORMONES IN THE TREATMENT OF NERVOUS AND MENTAL DISEASE: PRESENT STATUS AND DEVELOPMENT , Pages 995-1003 , A.J. PRANGE JR., C.B. NEMEROFF, M.A. LIPTON, G. BISSETTE, G.R. BREESE, P.T. LOOSEN, I.C. WILSON SUMMARY OF THE SESSION , Pages 1007-1009 , Leo E. HOLLISTER PSYCHOPHARMACOLOGY RESEARCH: AN ATTEMPT AT AN OVERVIEW , Pages 1011-1018 , J. LEVINE CLINICAL PHARMACOLOGY AND PHARMACOTHERAPY , Pages 1019-1021 , L.E. HOLLISTER DRUG EVALUATION , Pages 1023-1031 , J. ANGST ALCOHOL AND DRUG-RELATED PROBLEMS , Pages 1033-1055 , C. RADOUCO-THOMAS, F. GARCIN, S. RADOUCO-THOMAS, D. LACROIX SUMMARY OF THE SESSION , Pages 1059-1060 , H. HELMCHEN, B. MÜLLER-OERLINGHAUSEN EFFECTS OF NEUROLEPTICS ON THE METABOLISM OF TRICYCLIC ANTIDEPRESSANTS , Pages 1061-1066 , L.F. GRAM TRICYCLICS AND MAO INHIBITORS: RATIONAL POLYPHARMACY IN TREATMENT–RESISTANT DEPRESSIONS , Pages 1067-1083 , B. SHOPSIN INTERACTION BETWEEN LITHIUM AND OTHER PSYCHOTROPIC DRUGS , Pages 1085-1094 , B. MÜLLER-OERLINGHAUSEN DRUG INTERACTIONS IN THE COURSE OF MAINTENANCE THERAPY WITH NEUROLEPTICS , Pages 1095-1098 , M.M. AMIN, T.A. BAN INTERACTION OF NEUROLEPTICS CLOZAPINE AND HALOPERIDOL , Pages 1099-1106 , E. RÜTHER THE EFFECT OF LITHIUM IN DEPRESSIVE SUBTYPES , Pages 1109-1115 , D.L. DUNNER, R. FIEVE LITHIUM-RESPONSIVE DEPRESSIVE ILLNESS: CLINICAL AND BIOLOGICAL CHARACTERISTICS , Pages 1117-1124 , T.A. RAMSEY, J. MENDELS LYMPHOCYTE AND ERYTHROCYTE ANTIGENS IN MANIC-MELANCHOLIC MODE , Pages 1125-1128 , O.J. RAFAELSEN, L.P. RYDER, R.W. SHAPIRO, A. SVEJGAARD CLINICAL PARADOXES FROM TYPOLOGIES OF DEPRESSION , Pages 1129-1133 , L.E. HOLLISTER SUMMARY OF THE SESSION , Pages 1137-1140 , T.M. ITIL ELECTROENCEPHALOGRAPHY STATISTICAL SPECTRAL ANALYSIS AND NEW TRENDS OF QUANTITATIVE ELECTROENCEPHALOGRAPHY , Pages 1141-1150 , B. PIDOUX, G. VERDEAUX, P. ETEVENON, P. PERON-MAGNAN, P. RIOUX, J.R. BOISSIER, P. DENIKER METHODOLOGICAL CONSIDERATIONS IN QUANTITATIVE PHARMACO-ELECTROENCEPHALOGRAPHY , Pages 1151-1164 , M. MATEJCEK QUANTITATIVE ELECTROENCEPHALOGRAPHY OF “CLASSICAL” PSYCHOACTIVE DRUGS , Pages 1165-1171 , L. GOLDSTEIN QUANTITATIVE ELECTROENCEPHALOGRAPHY IN PSYCHIATRIC RESEARCH , Pages 1173-1182 , E.A. SERAFETINIDES QUANTITATIVE PHARMACO-ELECTROENCEPHALOGRAPHY IN THE DISCOVERY OF PSYCHOTROPIC PROPERTIES OF DRUGS , Pages 1183-1190 , T.M. ITIL CLINICAL SIGNIFICANCE AND METHODOLOGICAL PROBLEMS OF QUANTITATIVE ELECTROENCEPHALOGRAPHY IN THE DISCOVERY AND THE PREDICTION OF PSYCHOTROPIC PROPERTIES OF A NEWLY DEVELOPED SUBSTANCE , Pages 1191-1202 , M. SAITO ELECTROENCEPHALOGRAPHIC MEASURES FOR PHARMACODYNAMIC ANALYSIS OF PSYCHOACTIVE DRUGS IN MAN , Pages 1203-1207 , M. FINK, P. IRWIN QUANTITATIVE ELECTROENCEPHALOGRAPHY OF CIRCULATORY PSYCHOTROPIC DRUGS , Pages 1209-1218 , J. ROUBICEK COMPUTER ELECTROENCEPHALOGRAPHY FINDINGS WITH LISURIDE: An Example for the Quantification of CNS Effects of a Circulatory Drug by Analyzing Bioelectrical Brain Potentials , Pages 1219-1223 , W.M. HERRMANN SUMMARY OF THE SESSION , Pages 1227-1228 , M.C. BRAUDE, H.L. TRENHOLM EXPERIMENTAL PHARMACODEPENDENCE. OPIATE AND AMPHETAMINE INTRAVENOUS SELF-ADMINISTRATION ANIMAL MODELS , Pages 1229-1247 , F. GARCIN, Simone RADOUCO-THOMAS, F. PERUSSE, R.N. GROVE, J. GAUTIER, C. RADOUCO-THOMAS PSYCHOSES AND OTHER ADVERSE PSYCHIATRIC REACTIONS ASSOCIATED WITH MARIHUANA , Pages 1249-1261 , R.E. MEYER LES PHARMACOPSYCHOSES COMME MODELE D'ETUDE DES PSYCHOSES EN PSYCHIATRIE BIOLOGIQUE , Pages 1263-1271 , M.J. COTTEREAU, N. DASKALOPOULOS, P. DENIKER LICIT AND ILLICIT DRUGS: PATTERNS OF USE , Pages 1273-1281 , J.J. SCHWAB, A. BERGER, N. TRAVEN, G.J. WARHEIT PATTERNS OF DRUG ABUSE IN CANADA , Pages 1283-1290 , H.L. TRENHOLM, I. ROOTMAN, S.P. HACKLAND SUMMARY OF THE SESSION , Pages 1293-1294 , A. HERZ OPIATE RECEPTOR BINDING STUDIES IN RAT BRAIN DURING MORPHINE PRIMARY DEPENDENCE AND EARLY ABSTINENCE , Pages 1295-1305 , F. GARCIN DEPENDENCE LIABILITY OF OPIATE-LIKE PEPTIDES , Pages 1307-1312 , A. HERZ, J. BLÄSIG, J. FRY, R. SCHULZ, W. ZIEGLGÄNSBERGER CONFORMATIONAL STATES OF THE OPIATE RECEPTOR , Pages 1313-1321 , E.J. SIMON, K.D. STAHL, J.M. HILLER CHARACTERISTICS OF OPIOID PEPTIDES FROM BRAIN AND PITUITARY , Pages 1323-1329 , B.M. COX, S. GENTLEMAN, L.I. LOWNEY, A. GOLDSTEIN MECHANISM OF OPIATE DEPENDENCE ELUCIDATED BY ANALYSIS OF THE INTERACTION BETWEEN OPIATES AND METHYLXANTHINES , Pages 1331-1338 , H.O.J. COLLIER, N.M. BUTT, D.L. FRANCIS, A.C. ROY, C. SCHNEIDER EFFECT OF CALCIUM AND LANTHANUM IN MORPHINE ANALGESIA AND TOLERANCE , Pages 1339-1345 , E.L. WAY, R.A. HARRIS, H. YAMAMOTO, E.T. IWAMOTO, H.H. LOH SUMMARY OF THE SESSION , Page 1349 , M.R.V. MURTHY, C. KORNETSKY DEVELOPMENT OF MONOAMINE NEURONS AND EFFECTS OF PSYCHOTROPIC DRUGS , Pages 1351-1353,1355-1361 , P. LUNDBORG, J. ENGEL CHANGING RELATIONSHIPS AMONG NEUROTRANSMITTER SYSTEMS IN DEVELOPING STRIATUM: IMPLICATIONS FOR NEURO-PSYCHOPHARMACOLOGY , Pages 1363-1370 , J.T. COYLE, R. ZACZEK, P. CAMPOCHIARO PHYSIOLOGICAL ASPECTS OF RAT CENTRAL NERVOUS SYSTEM MATURATION , Pages 1371-1377 , J. SCHERRER, H. AXELRAD, R. VERLEY THE ONTOGENETIC DEVELOPMENT OF THE OPIATE RECEPTOR AND ENKEPHALIN IN RAT BRAIN , Pages 1379-1385 , F. GARCIN, J.T. COYLE MOLECULAR CORRELATES OF BRAIN DEVELOPMENT: tRNA AS A POSSIBLE INTERMEDIATE IN THE FORMATION OF NEUROACTIVE SUBSTANCES , Pages 1387-1394 , M.R.V. MURTHY, H. ROUX-MURTHY, A.D. BHARUCHA, K.D. CHAUDHARY, R. CHARBONNEAU BEHAVIORAL CONSEQUENCES OF VERY EARLY DEVELOPMENTAL EXPOSURE TO CHLORPROMAZINE IN RATS , Pages 1395-1401 , M. GOLUB, C. KORNETSKY CEREBRAL TRACE AMINES: THEIR FUNCTION AND RELEVANCE , Pages 1405-1412 , A.A. BOULTON NEGATIVE REINFORCING PROPERTIES OF PSYCHOTROPIC DRUGS , Pages 1413-1415,1417-1422 , F. HOFFMEISTER DESENSITIZATION OF ß -ADRENERGIC RECEPTORS BY ß-ADRENERGIC AGONISTS , Pages 1423-1435 , R.J. LEFKOWITZ NORADRENERGIC NEURONS: POST-STIMULATION INCREASE IN CATECHOLAMINE BIOSYNTHESIS , Pages 1439-1441,1443-1455 , P.M. SALZMAN, R.H. ROTH MODE OF REGULATION OF TYROSINE HYDROXYLASE: INDUCTION AND ACTIVATION , Pages 1457-1465 , T.H. JOH, D.J. REIS REGULATION OF TYROSINE HYDROXYLASE IN SUPERIOR CERVICAL GANGLIA , Pages 1467-1470 , I. HANBAUER SUMMARY OF THE SESSION , Pages 1473-1475 , C.R. SCHUSTER, R. STRETCHt PHARMACOLOGICAL MODIFICATION OF COCAINE AND APOMORPHINE SELF-ADMINISTRATION IN THE SQUIRREL MONKEY , Pages 1477-1484 , C.A. GILL, W.C. HOLZ, C.L. ZIRKLE, H. HILL CHLORPROMAZINE-AND HALOPERIDOL-INDUCED CHANGES IN SOME BEHAVIORAL EFFECTS OF COCAINE AND AMPHETAMINE , Pages 1485-1502 , J.H. WOODS, S. HERLING, G. WINGER COMPARISON OF THE EFFECTS OF THE INTRAVENOUS AND INTRACEREBRAL ROUTES OF NALOXONE AND DIALLYLNORMORPHINE ADMINISTRATION IN THE MORPHINE-DEPENDENT RHESUS MONKEY , Pages 1503-1512 , J.R. SANCHEZ-RAMOS, C.R. SCHUSTER DISCRETE-TRIAL CONTROL OF MORPHINE SELF-INJECTION BEHAVIOUR IN SQUIRREL MONKEYS: EFFECTS OF NALOXONE AND CHLORPROMAZINE PRE-TREATMENTS , Pages 1513-1522 , R. STRETCH SUPPRESSION OF INTRAVENOUS DRUG SELF-ADMINISTRATION BY PUNISHMENT IN MONKEYS: SELECTED OBSERVATIONS , Pages 1523-1530 , R.N. GROVE DISCUSSION OF THE SESSION TOPIC , Pages 1531-1533 , P.B. DEWS SUMMARY OF THE SESSION , Page 1537 , H.C.B. DENBER PHARMACOTHERAPY AS AN AID TO MORE EFFECTIVE PSYCHOTHERAPY , Pages 1539-1544 , Y.D. LAPIERRE THE “TOTAL PATIENT” IN RELATION TO PSYCHOPHARMACOLOGY , Pages 1545-1548 , E.K. KORANYI TOTAL TREATMENT OF THE PATIENT , Pages 1549-1552 , H.C.B. DENBER SUMMARY OF THE SESSION , Pages 1555-1556 , D.P. BOBON, J. SAARMA PREGNANCY AND INFANCY OF THE GERMAN-SWISS AMP SYSTEM , Pages 1557-1559 , H. HELMCHEN INTRODUCTORY REMARKS ON THE REVISION OF THE AMP SYSTEM MANUAL , Pages 1561-1564 , J. FLEISCHHAUER FIRST TRANSLATION OF THE AMP SYSTEM: THE CROATIAN ONE , Pages 1565-1568 , N. BOHAČEK EXPERIENCES WITH THE RUSSIAN AND ESTHONIAN TRANSLATIONS OF THE AMP PSYCHOPATHOLOGY SCALE IN DEPRESSION AND SCHIZOPHRENIA , Pages 1569-1570 , J. SAARMA, G. MOROZOV THE AMP SYSTEM: PROGRESS IN THE SPANISH TRANSLATION , Pages 1571-1573 , G. HEINZE THE AMP SYSTEM IN ENGLISH , Pages 1575-1579 , T.A. BAN THE IMPLICATIONS OF THE AMP SYSTEM IN CANADIAN PSYCHIATRY , Pages 1581-1582 , Y.D. LAPIERRE CONCEPTUAL AND SEMANTIC PROBLEMS RAISED BY THE FRENCH TRANSLATION OF THE AMP PSYCHOPATHOLOGY SCALE , Pages 1583-1588 , D.P. BOBON INTRODUCTION , Pages 1591-1592 , E. USDIN THE NINCDS/NIMH HUMAN NEUROSPECIMEN BANK , Pages 1593-1595 , W.W. TOURTELLOTTE, R.C. COHENOUR, J. RAJ, A. MORGAN, R. WARWICK, J. SWEEDER, J. SELMAN, A. COSTANZA METHODOLOGICAL ASPECTS OF POST-MORTEM INVESTIGATIONS OF HUMAN BRAIN -WITH SPECIAL REFERENCE TO MONOAMINES AND RELATED ENZYMES , Pages 1597-1604 , R. ADOLFSSON, C.G. GOTTFRIES, B. WINBLAD MASS FRAGMENTOGRAPHIC DETERMINATION OF FREE AND CONJUGATED MONOAMINE METABOLITES IN HUMAN BRAIN TISSUE OBTAINED AT AUTOPSY , Pages 1605-1608 , G. SEDVALL, F.-A. WIESEL BRAIN BANKS FROM THE POINT OF VIEW OF THE PSYCHIATRIST , Pages 1609-1610 , T.A. BAN, M.M. AMIN SUMMARY OF THE SESSION , Pages 1613-1614 , E.F. DOMINO, C. GIURGEA MOLECULAR BIOLOGICAL MODELS IN GERIATRIC NEUROBIOLOGY , Pages 1615-1622 , M.R.V. MURTHY, A.D. BHARUCHA, H. ROUX-MURTHY, J. JACOBt, P.K. RANJEKAR CENTRAL HYPOXIA MODELS AND CORRELATIONS WITH AGING BRAIN , Pages 1623-1631 , C. GIURGEAt, F. MOURAVIEFF-LESUISSE NEURONAL LIPOFUSCIN AND LEARNING DEFICITS IN AGING MAMMALS , Pages 1633-1639,1641-1645 , K. NANDY, H. LAL BIOCHEMICAL CHANGES IN CENTRAL CATECHOLAMINERGIC NEURONS OF THE SENESCENT RATS , Pages 1647-1654 , S. ALGERI, M. BONATI, N. BRUNELLO, F. PONZIO, G. STRAMENTINOLI, M. GUALANO BRAIN CHOLINERGIC DEFICITS IN SENESCENT ANIMALS , Pages 1655-1658 , E.F. DOMINO DISCUSSION , Pages 1659-1660 , J.T. COYLE THERMOREGULATION AS A MODEL IN GERIATRIC NEURO-PSYCHOPHARMACOLOGY , Pages 1661-1667 , H. COPER, G. SCHULZE, P. BÜRGEL DISTURBED VIGILANCE REGULATION AS A MODEL OF GERIATRIC NEUROPSYCHOPHARMACOLOGY , Pages 1669-1671 , S. KANOWSKI, H. COPER TRICYCLIC DRUG TREATMENT IN THE ELDERLY PATIENT , Pages 1673-1676 , D.T. GIANTURCO, M. LINNOILA EVALUATION OF TWO GERIATRIC BEHAVIORAL RATING SCALES , Pages 1677-1683 , W. GUY, P. CLEARY PERSPECTIVES IN GERIATRIC NEURO-PSYCHOPHARMACOLOGY , Pages 1685-1687 , H.E. LEHMANN SUMMARY OF THE SESSION , Pages 1691-1692 , A.A. LEEDS COMMUNICATIONS IN NEURO-PSYCHOPHARMACOLOGY: VIEWPOINT FROM THE WORLD HEALTH ORGANIZATION , Pages 1693-1696 , F.E. VARTANIAN, N. SARTORIUS INFORMATION DISSEMINATION IN NEURO-PSYCHOPHARMACOLOGY: VIEWPOINT FROM THE WHO INTERNATIONAL REFERENCE CENTER FOR PSYCHOTROPIC DRUGS , Pages 1697-1698 , A.A. LEEDS COMMUNICATION IN NEURO-PSYCHOPHARMACOLOGY. VIEWPOINT FROM A WHO REGIONAL REFERENCE CENTER FOR PSYCHOTROPIC DRUGS , Pages 1699-1700 , P. KIELHOLZ, J. FLEISCHHAUER COLLABORATIVE REFERENCE CENTER: ROLE AND FUNCTIONS , Pages 1701-1703 , T.A. BAN COMMUNICATION THROUGH PUBLICATIONS , Pages 1705-1707 , A.A. LEEDS COMPUTER AND AUDIO-VISUAL COMMUNICATION CHANNELS OF DRUG INFORMATION , Pages 1709-1710 , D.P. BOBON, R. von FRENCKELL COMMUNICATION NEEDS IN NEURO-PSYCHOPHARMACOLOGY FROM THE TEACHER'S POINT OF VIEW , Pages 1711-1712 , T.A. BAN THE FUTURE OF COMMUNICATIONS IN NEURO-PSYCHOPHARMACOLOGY , Pages 1713-1715 , H.E. LEHMANN PRESIDENTIAL ADDRESS OF THE CLOSING SESSION , Pages 1719-1720 , L.E. HOLLISTER SUBJECT INDEX , Pages 1721-1737