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عصب‌شناسی شبکه‌ای

Network Neuroscience

جلد کتاب عصب‌شناسی شبکه‌ای

معرفی کتاب «عصب‌شناسی شبکه‌ای» (با عنوان لاتین Network Neuroscience) نوشتهٔ Flavio Fröhlich، منتشرشده توسط نشر Academic Press در سال 2016. این کتاب در فرمت pdf، زبان انگلیسی ارائه شده است.

Studying brain networks has become a truly interdisciplinary endeavor, attracting students and seasoned researchers alike from a wide variety of academic backgrounds. What has been lacking is an introductory textbook that brings together the different fields and provides a gentle introduction to the major concepts and findings in the emerging field of network neuroscience. __Network Neuroscience__ is a one-stop-shop that is of equal use to the neurobiologist, who is interested in understanding the quantitative methods employed in network neuroscience, and to the physicist or engineer, who is interested in neuroscience applications of mathematical and engineering tools. The book spans 27 chapters that cover everything from individual cells all the way to complex network disorders such as depression and autism spectrum disorders. An additional 12 toolboxes provide the necessary background for making network neuroscience accessible independent of the reader’s background. Dr. Flavio Frohlich (www.networkneuroscientist.org) wrote this book based on his experience of mentoring dozens of trainees in the Frohlich Lab, from undergraduate students to senior researchers. The Frohlich lab (www.frohlichlab.org) pursues a unique and integrated vision that combines computer simulations, animal model studies, human studies, and clinical trials with the goal of developing novel brain stimulation treatments for psychiatric disorders. The book is based on a course he teaches at UNC that has attracted trainees from many different departments, including neuroscience, biomedical engineering, psychology, cell biology, physiology, neurology, and psychiatry. Dr. Frohlich has consistently received rave reviews for his teaching. With this book he hopes to make his integrated view of neuroscience available to trainees and researchers on a global scale. His goal is to make the book the training manual for the next generation of (network) neuroscientists, who will be fusing biology, engineering, and medicine to unravel the big questions about the brain and to revolutionize psychiatry and neurology. * Easy-to-read, comprehensive introduction to the emerging field of network neuroscience * Includes 27 chapters packed with information on topics from single neurons to complex network disorders such as depression and autism * Features 12 toolboxes serve as primers to provide essential background knowledge in the fields of biology, mathematics, engineering, and physics Studying Brain Networks Has Become A Truly Interdisciplinary Endeavor, Attracting Students And Seasoned Researchers Alike From A Wide Variety Of Academic Backgrounds. What Has Been Lacking Is An Introductory Textbook That Brings Together The Different Fields And Provides A Gentle Introduction To The Major Concepts And Findings In The Emerging Field Of Network Neuroscience. Network Neuroscience Is A One-stop-shop That Is Of Equal Use To The Neurobiologist, Who Is Interested In Understanding The Quantitative Methods Employed In Network Neuroscience, And To The Physicist Or Engineer, Who Is Interested In Neuroscience Applications Of Mathematical And Engineering Tools. The Book Spans 27 Chapters That Cover Everything From Individual Cells All The Way To Complex Network Disorders Such As Depression And Autism Spectrum Disorders. An Additional 12 Toolboxes Provide The Necessary Background For Making Network Neuroscience Accessible Independent Of The Reader's Background. Dr.^ Flavio Frohlich (www.networkneuroscientist.org) Wrote This Book Based On His Experience Of Mentoring Dozens Of Trainees In The Frohlich Lab, From Undergraduate Students To Senior Researchers. The Frohlich Lab (www.frohlichlab.org) Pursues A Unique And Integrated Vision That Combines Computer Simulations, Animal Model Studies, Human Studies, And Clinical Trials With The Goal Of Developing Novel Brain Stimulation Treatments For Psychiatric Disorders. The Book Is Based On A Course He Teaches At Unc That Has Attracted Trainees From Many Different Departments, Including Neuroscience, Biomedical Engineering, Psychology, Cell Biology, Physiology, Neurology, And Psychiatry. Dr. Frohlich Has Consistently Received Rave Reviews For His Teaching. With This Book He Hopes To Make His Integrated View Of Neuroscience Available To Trainees And Researchers On A Global Scale.^ His Goal Is To Make The Book The Training Manual For The Next Generation Of (network) Neuroscientists, Who Will Be Fusing Biology, Engineering, And Medicine To Unravel The Big Questions About The Brain And To Revolutionize Psychiatry And Neurology. Front Cover; Network Neuroscience; Network Neuroscience; Copyright; Dedication; Contents; Preface; Introduction; References; I -- Neurons, Synapses, And Circuits; 1 -- Membrane Voltage ; Membrane Voltage And Ionic Currents; Measuring The Membrane Voltage: Current Clamp; Measuring Ionic Currents: Voltage Clamp; Dynamic Clamp; Instrumentation; Sharp Micropipette Intracellular Recordings; Whole-cell Patch-clamp Recordings; Summary And Outlook; References; 2 -- Dynamics Of The Action Potential; Potassium Current; Sodium Current; Action Potentials; Summary And Outlook; Reference 3 -- Synaptic Transmissionthe Chemical Synapse; Presynaptic Voltage-gated Calcium Channels; Presynaptic Calcium Dynamics; Postsynaptic Glutamate Receptors; Modeling Excitatory Synaptic Transmission; Metabotropic Glutamate Receptors; Inhibitory Synaptic Transmission; Electrical Synapses; Summary And Outlook; References; 4 -- Synaptic Plasticity; Short-term Plasticity; Short-term Depression; Synaptic Facilitation; Modeling Short-term Plasticity; Long-term Plasticity; Mechanism Of Ltp And Ltd; Spike-timing-dependent Plasticity; Modeling Long-term Plasticity; Summary And Outlook; References 5 -- Neuromodulatorscortical State; Basic Principles; Acetylcholine; Mechanisms; Behavior; Dopamine; Mechanisms; Behavior; Norepinephrine; Mechanisms; Behavior; Histamine; Mechanisms; Behavior; Serotonin; Mechanisms; Behavior; Monoamine Transporters; Summary And Outlook; References; 6 -- Neuronal Communication Beyond Synapses; Chemical Signaling Beyond Synapses; Neuropeptides; Nitric Oxide; Extracellular Ion Concentration Dynamics; Endogenous Electric Fields; Summary And Outlook; References; 7 -- Microcircuits Of The Neocortex; Glutamatergic Cells; Pyramidal Cells; Spiny Stellate Cells Inhibitory Interneuronsbasket Cells; Other Types Of Inhibitory Interneurons; The Cortical Microcircuit; Layered Circuits Of The Neocortex; Inhibitory Circuits; Summary And Outlook; References; 8 -- Microcircuits Of The Hippocampus; Circuit Layout Of The Hippocampus; Dentate Gyrus; Hippocampal Fields: Ca1, Ca2, And Ca3; Ca1 Pyramidal Cells; Ca3 Pyramidal Cells; Subiculum; Entorhinal Cortex; Fundamental Local Circuit Principles; Excitatory Circuit Motifs; Inhibitory Circuit Motifs; Summary And Outlook; Notes; References; Ii -- Measuring, Perturbing, And Analyzing Brain Networks; 9 -- Unit Activity Terminology And Conceptsorigin Of The Eap Signal; Recording Strategies; Spike Sorting; Analyzing And Visualizing Unit Activity; Summary And Outlook; References; 10 -- Lfp And Eeg; Electric Fields Caused By Network Activity; Electroencephalogram; Local Field Potential; Data Analysis; Source Localization; Invasive Recording In Humans; Magnetoencephalography; Summary And Outlook; References; 11 -- Optical Measurements And Perturbations; Calcium Imaging; Calcium Indicators; Calcium Imaging Setup; Applications; Voltage-sensitive Dye Imaging; Vsdi Setup; Applications; Optogenetics Flavio Frohlich. Includes Bibliographical References And Index. Mode Of Access: World Wide Web.

Studying brain networks has become a truly interdisciplinary endeavor, attracting students and seasoned researchers alike from a wide variety of academic backgrounds. What has been lacking is an introductory textbook that brings together the different fields and provides a gentle introduction to the major concepts and findings in the emerging field of network neuroscience. Network Neuroscience is a one-stop-shop that is of equal use to the neurobiologist, who is interested in understanding the quantitative methods employed in network neuroscience, and to the physicist or engineer, who is interested in neuroscience applications of mathematical and engineering tools. The book spans 27 chapters that cover everything from individual cells all the way to complex network disorders such as depression and autism spectrum disorders. An additional 12 toolboxes provide the necessary background for making network neuroscience accessible independent of the reader’s background.

Dr. Flavio Frohlich wrote this book based on his experience of mentoring dozens of trainees in the Frohlich Lab, from undergraduate students to senior researchers. The Frohlich lab pursues a unique and integrated vision that combines computer simulations, animal model studies, human studies, and clinical trials with the goal of developing novel brain stimulation treatments for psychiatric disorders. The book is based on a course he teaches at UNC that has attracted trainees from many different departments, including neuroscience, biomedical engineering, psychology, cell biology, physiology, neurology, and psychiatry. Dr. Frohlich has consistently received rave reviews for his teaching. With this book he hopes to make his integrated view of neuroscience available to trainees and researchers on a global scale. His goal is to make the book the training manual for the next generation of (network) neuroscientists, who will be fusing biology, engineering, and medicine to unravel the big questions about the brain and to revolutionize psychiatry and neurology.

  • Easy-to-read, comprehensive introduction to the emerging field of network neuroscience
  • Includes 27 chapters packed with information on topics from single neurons to complex network disorders such as depression and autism
  • Features 12 toolboxes serve as primers to provide essential background knowledge in the fields of biology, mathematics, engineering, and physics
Content: Front Matter,Copyright,Dedication,Preface,IntroductionEntitled to full textIntroduction, Page 1 Chapter 1 - Membrane Voltage, Pages 3-17 Chapter 2 - Dynamics of the Action Potential, Pages 19-28 Chapter 3 - Synaptic Transmission, Pages 29-45 Chapter 4 - Synaptic Plasticity, Pages 47-58 Chapter 5 - Neuromodulators, Pages 59-71 Chapter 6 - Neuronal Communication Beyond Synapses, Pages 73-84 Chapter 7 - Microcircuits of the Neocortex, Pages 85-95 Chapter 8 - Microcircuits of the Hippocampus, Pages 97-109 Introduction, Pages 111-113 Chapter 9 - Unit Activity, Pages 115-126 Chapter 10 - LFP and EEG, Pages 127-143 Chapter 11 - Optical Measurements and Perturbations, Pages 145-159 Chapter 12 - Imaging Structural Networks With MRI, Pages 161-176 Chapter 13 - Imaging Functional Networks With MRI, Pages 177-185 Chapter 14 - Deep Brain Stimulation, Pages 187-196 Chapter 15 - Noninvasive Brain Stimulation, Pages 197-210 Chapter 16 - Network Interactions, Pages 211-224 Introduction, Pages 225-229 Chapter 17 - Low-Frequency Oscillations, Pages 231-242 Chapter 18 - Theta Oscillations, Pages 243-250 Chapter 19 - Alpha Oscillations, Pages 251-260 Chapter 20 - Beta Oscillations, Pages 261-270 Chapter 21 - Gamma Oscillations, Pages 271-280 Chapter 22 - High-Frequency Oscillations, Pages 281-288 Introduction, Pages 289-290 Chapter 23 - Parkinson's Disease, Pages 291-296 Chapter 24 - Epilepsy, Pages 297-308 Chapter 25 - Schizophrenia, Pages 309-318 Chapter 26 - Autism Spectrum Disorders, Pages 319-324 Chapter 27 - Major Depressive Disorder, Pages 325-331 Introduction, Page 333 Toolbox Neurons, Pages 335-340 Toolbox Animal Models, Pages 341-349 Toolbox Neurology, Pages 351-356 Toolbox Psychiatry, Pages 357-362 Toolbox Matlab, Pages 363-375 Toolbox Electrical Circuits, Pages 377-389 Toolbox Differential Equations, Pages 391-397 Toolbox Dynamical Systems, Pages 399-404 Toolbox Graph Theory, Pages 405-411 Toolbox Modeling Neurons, Pages 413-423 Toolbox Physics of Electric Fields, Pages 425-433 Toolbox Time and Frequency, Pages 435-442 Index, Pages 443-464
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