Mutagenicity. New Horizons in Genetic Toxicology (Cell biology)

Mutagenicity: New Horizons in Genetic Toxicology provides an overview of the various applications and studies in the field of genetic toxicology and environmental mutagenesis. The book is composed of selected scientific papers written by experts in the field. The text presents topics on naturally occurring mutagens; occupational carcinogen; and evaluation of cooking methods. Experiments on mammalian cell mutation; chromosomal aberrations; and organisms that can be used as environmental monitors of toxicity are discussed as well. Ecologists, environmental and sanitary engineers, toxicologists, and anyone interested in environmental mutagenesis, genetic toxicology, occupational health, or the regulation of toxic substances will find the book a good source of insight. Content: Front Matter , Page iii Copyright , Page iv List of Contributors , Pages xiii-xiv Preface , Pages xv-xvi , John A. Heddle Chapter 1 - Screening Chemicals for Mutagenicity: Practices and Pitfalls , Pages 1-33 , John Ashby Chapter 2 - Qualitative and Quantitative Comparisons between Mutagenic and Carcinogenic Activities of Chemicals , Pages 35-72 , H. Bartsch, L. Tomatis, C. Malaveille Chapter 3 - The Use of Mutagenicity to Evaluate Carcinogenic Hazards in Our Daily Lives , Pages 73-88 , Takashi Sugimura, Minako Nagao Chapter 4 - Mutagenicity and Lung Cancer in a Steel Foundry Environment , Pages 89-115 , D.W. Bryant, D.R. McCalla Chapter 5 - The Use of Mutagenicity Testing to Evaluate Food Products , Pages 117-142 , H.F. Stick, M.P. Rosin, C.H. Wu, W.D. Powrie Chapter 6 - Transformation of Somatic Cells in Culture , Pages 143-169 , Andrew Sivak, Alice S. Tu Chapter 7 - Mutagenicity Testing with Cultured Mammalian Cells: Cytogenetic Assays , Pages 171-213 , A.T. Natarajan, G. Obe Chapter 8 - Measurement of Mutations in Somatic Cells in Culture , Pages 215-240 , Veronica M. Maher, J. Justin McCormick Chapter 9 - Chromosomal Aberrations Induced in Occupationally Exposed Persons , Pages 241-266 , Maria Kučerová Chapter 10 - The Rationale and Methodology for Quantifying Sister Chromatid Exchange in Humans , Pages 267-304 , Anthony V. Carrano, Dan H. Moore II Chapter 11 - The 6-Thioguanine-Resistant Peripheral Blood Lymphocyte Assay for Direct Mutagenicity Testing in Humans , Pages 305-336 , Richard J. Albertini, David L. Sylwester, Elizabeth F. Allen Chapter 12 - Sperm Assays as Indicators of Chemically Induced Germ-Cell Damage in Man , Pages 337-350 , A.J. Wyrobek Chapter 13 - Cytogenetic Events in Vivo , Pages 351-384 , J.G. Brewen, D.G. Stetka Chapter 14 - Dominant Skeletal Mutations: Applications in Mutagenicity Testing and Risk Estimation , Pages 385-406 , Paul B. Selby Chapter 15 - Plants as Sensitive in Situ Detectors of Atmospheric Mutagens , Pages 407-434 , William F. Grant, K.D. Zura Chapter 16 - Fishes as Biological Detectors of the Effects of Genotoxic Agents , Pages 435-456 , A.D. Kligerman Index , Pages 457-471 CELL BIOLOGY: A Series of Monographs , Pages ibc1-ibc2