Muscle Diseases - A Guide to Differential Diagnosis, Investigation and Management (Feb 5, 2025)_(1138368024)_(CRC Press).pdf

A how-to-guide on the clinical assessment and investigation of patients presenting with muscle-related symptoms. Featuring a case-based approach, this accessible text is suitable for a wide range of clinical specialists who see patients presenting with both common and rare muscle diseases. Muscle diseases are often initially missed or misdiagnosed as they are uncommon disorders and can present in a variety of ways, often mimicking other more common disorders. Careful assessment of the history, physical examination and appropriate choice of investigations is therefore essential to reaching a diagnosis and providing short and long-term effective management plans. Key features of this resource include: - A case-based approach: using real cases seen in clinical practice and highlighting different clinical presentations. - Providing case vignettes that cover patient history, examination, investigations, diagnosis, and discussion points to assist the reader in developing a mental framework for thinking about muscle disease and approaching diagnosis. - Highlighting the relevant investigations (including muscle biopsy, neurophysiology, and muscle imaging) required for each clinical scenario, aiding the clinician in clinicopathological correlation. - Being concise, practical, and complemented by a wide range of figures to enhance understanding. Patients with muscle diseases may be referred to one of several medical or surgical specialties including neurology, rheumatology, neuropathology, neurophysiology, cardiology, respiratory medicine, intensive care medicine, gastroenterology, ophthalmology, orthopaedic and spinal surgery, before the correct diagnosis is considered. This accessible text is an ideal resource for clinicians. Cover Half Title Title Page Copyright Page Dedication Table of Contents Preface About the Editors List of Contributors Introduction Abbreviations Chapter 1 History Chapter 2 Muscle examination Chapter 3 Serological tests Chapter 4 Muscle antibodies Chapter 5 Neurophysiology Chapter 6 Muscle biopsy Chapter 7 Muscle imaging Chapter 8 Genetic investigations in neuromuscular diseases Chapter 9 Management, treatment and therapy for neuromuscular conditions Chapter 10 Closing comments Section Cases Case 1 Case 2 Case 3 Case 4 Case 5 Case 6 Case 7 Case 8 Case 9 Case 10 Case 11 Case 12 Case 13 Case 14 Case 15 Case 16 Case 17 Case 18 Case 19 Case 20 Case 21 Case 22 Case 23 Case 24 Case 25 Case 26 Case 27 Case 28 Case 29 Case 30 Case 31 Case 32 Case 33 Case 34 Case 35 Case 36 Index