Multidisciplinary treatment of colorectal cancer : staging -- treatment -- pathology -- palliation

This book is a comprehensive reference work on the multidisciplinary team (MDT) management of colorectal cancer (CRC) patients that will meet the needs of all members of CRC MDTs and those training in the field. Important, up-to-date knowledge is provided on organization of MDTs, early intervention, surgery, oncology, imaging, pathology, and palliation, with special focus on controversies. This second edition has been thoroughly revised. It includes an entirely new section on the principles of treatment of significant polyps and early cancers and a total of 14 new chapters, including one on the early integration of palliative care. Every effort has been made to ensure that each specialty-specific chapter will be approachable for all team members, thereby facilitating an effective interdisciplinary approach to teamwork. The authors are leading European doctors and scientists who have influenced the development of the MDT concept as well as other aspects of individualized treatment of CRC patients. Front Matter ....Pages i-xiv Front Matter ....Pages 1-1 Organizing the Multidisciplinary Team (Gunnar Baatrup)....Pages 3-9 Multidisciplinary Treatment: Influence on Outcomes (Arne Wibe)....Pages 11-21 Decisions in the Multidisciplinary Team: Influence of Disease-, Treatment- and Patient-Related Factors (Birger Henning Endreseth, Tore Stornes)....Pages 23-34 Meeting the Challenge of Increased Specialisation (Marianne K. Thygesen)....Pages 35-38 Front Matter ....Pages 39-39 Early Intervention for Colorectal Cancer: Introduction (Robert J. C. Steele)....Pages 41-42 Significant Polyp and Early Colorectal Cancer (SPECC): A National Development Program (Neil Borley)....Pages 43-46 Management of Rectal Neoplasia (Issam al-Najami, Ravish Narotam Jootun)....Pages 47-54 Local Excision of Rectal Cancer After Neoadjuvant Treatment (Johannes H. W. de Wilt, Simon P. Bach)....Pages 55-62 Front Matter ....Pages 63-63 Introduction to Surgery (Hartwig Kørner, Lars Påhlman)....Pages 65-72 Surgical Research (Kjetil Søreide, Hartwig Kørner)....Pages 73-77 Surgical Anatomy of the Rectum and the TME Specimen (Total Mesorectal Excision) (R. J. Heald, Brendan J. Moran)....Pages 79-92 Major Resections in Rectal Cancer (Ionica Daniel Vilcea, Cecil Sorin Mirea)....Pages 93-120 Locally Advanced and Recurrent Cancer (K. Havenga, A. W. Wijsmuller, T. Wiggers)....Pages 121-128 Reconstructions After Neoadjuvant and Abdominoperineal Resection (Søren Laurberg, Marie-Louise Feddern)....Pages 129-132 Low Anterior Resection Syndrome (Katrine J. Emmertsen)....Pages 133-139 Surgical Anatomy of the Colon and Complete Mesocolic Excision (C. A. Bertelsen, Danilo Miskovic)....Pages 141-155 Front Matter ....Pages 157-157 Introduction to Oncology (Per Pfeiffer, Camilla Qvortrup)....Pages 159-161 Multidisciplinary Treatment of Rectal Cancer (Bengt Glimelius)....Pages 163-178 Adjuvant Therapy in Patients with Colorectal Cancer (Camilla Qvortrup, Per Pfeiffer)....Pages 179-182 Immunotherapy in Patients with mCRC (Lars Bastholt, Camilla Qvortrup, Per Pfeiffer)....Pages 183-186 Chemotherapy and Targeted Drugs for Patients with Metastatic Colorectal Cancer (Per Pfeiffer, Camilla Qvortrup)....Pages 187-202 Chemoradiotherapy for Locally Advanced T3/T4 Rectal Cancer: What Should We Do with Complete Responders? (Rob Glynne-Jones, Jyotsna Bhudia, Rob Hughes)....Pages 203-222 Front Matter ....Pages 223-223 Introduction: Preoperative Staging by Imaging (Regina G. H. Beets-Tan)....Pages 225-228 Cross-Sectional Imaging for Local Staging of Rectal Cancer (Doenja M. J. Lambregts, Regina G. H. Beets-Tan)....Pages 229-242 Dual-Energy CT (Issam al-Najami)....Pages 243-247 Evaluation of Tumour Response After Radiotherapy in Rectal Cancer (H. E. Haak, G. L. Beets)....Pages 249-256 Front Matter ....Pages 257-257 Introduction to the Pathology of Colorectal Cancer (Nigel Scott)....Pages 259-261 Early Colorectal Cancer (William Sterlacci, Michael Vieth)....Pages 263-277 Quality of Surgery (A. C. Westwood, Philip Quirke, N. P. West)....Pages 279-295 Staging of Colorectal Cancer (Including Staging After Neoadjuvant Therapy) (Iris Nagtegaal)....Pages 297-303 Molecular Pathology in Colorectal Cancer: Current Practice and Future Directions (K. M. Marks, A. C. Westwood, N. P. West)....Pages 305-315 Front Matter ....Pages 317-317 Multidisciplinary Treatment of Colorectal Cancer: The Palliative Care Team: Introduction (Dagny Faksvåg Haugen)....Pages 319-323 Surgical Treatment in Palliative Care (Hartwig Kørner, Jon Arne Søreide)....Pages 325-337