MR Imaging in White Matter Diseases of the Brain and Spinal Cord (Medical Radiology / Diagnostic Imaging)

In recent decades, the use of neuroimaging techniques has resulted in outstanding progress in the diagnosis and management of neurological diseases, and this is particularly true of those diseases that affect the white matter of the brain and spinal cord. This book, written by internationally acclaimed experts, comprises a series of comprehensive and up-to-date reviews on the use of MR imaging in these major neurological conditions. The diverse available MR techniques, such as magnetization transfer MRI, diffusion-weighted MRI, MR spectroscopy, functional MRI, cell-specific MRI, perfusion MRI, and microscopic imaging with ultra-high field MRI, offer an extraordinarily powerful means of gaining fundamental in vivo insights into disease processes. The strengths and weaknesses of all these techniques in the study of multiple sclerosis and other relevant diseases are extensively considered. After an introductory section on neuroimaging technology, subsequent sections address disorders of myelination, demyelinating diseases, immune-mediated disorders, and white matter disorders related to aging and other conditions. This book provides a valuable summary of the state of the art in the field, and defines important areas for future research. Basis of MRI Contrast....Pages 3-12 Hardware for Magnetic Resonance Imaging....Pages 13-28 Spin- and Gradient-Echo Imaging....Pages 29-40 Fast Imaging with an Introduction to k-Space....Pages 41-55 Magnetization Transfer....Pages 57-62 Quantitative Diffusion Imaging....Pages 63-81 MR Methods to Measure Cerebral Perfusion....Pages 83-91 Functional MRI....Pages 93-110 MR Spectroscopy....Pages 115-127 Molecular Imaging and High-Field MRI in Multiple Sclerosis....Pages 129-148 MR Imaging of Brain Development....Pages 151-175 Imaging of Inherited and Acquired Metabolic Brain Disorders....Pages 177-193 Proton MR Spectroscopy in Metabolic Disorders of the Central Nervous System....Pages 195-207 Conventional MRI Techniques in Multiple Sclerosis....Pages 211-223 Multiple Sclerosis: Other MR Techniques....Pages 225-240 Variants of Multiple Sclerosis....Pages 241-253 Acute Disseminated Encephalomyelitis....Pages 255-266 Demyelinating Diseases of the Spinal Cord....Pages 269-277 Demyelinating Diseases of the Optic Nerve....Pages 279-289 Primary Angiitis of the Central Nervous System....Pages 293-310 Neuro-Psychiatric Systemic Lupus Erythematosus....Pages 311-329 Non-MS Inflammatory Diseases of the CNS: MR Features in Addition to the White Matter....Pages 331-341 White Matter Pathology in Systemic Immune-Mediated Diseases....Pages 343-352 Neuroimaging of Normal Brain Aging....Pages 355-361 White Matter Abnormalities in Patients with Cerebrovascular Disease....Pages 363-375 Neurodegenerative Diseases with Associated White Matter Pathology....Pages 377-388 Viral and Non-Viral Infections in Immuno-competent and Immunocompromised Patients....Pages 391-409 Neoplastic Disorders....Pages 411-439 Head Trauma....Pages 441-451 Psychiatric Disorders....Pages 453-464 Comprises a series of comprehensive reviews on the use of MR imaging in neurological conditions. This book considers the strengths and weaknesses of various techniques in the study of multiple sclerosis and other relevant diseases. It provides a valuable summary of the state of the art in the field, and defines important areas for future research. M. Filippi ... [et Al.] (eds). ; With Contributions By R. Bammer ... [et Al.] ; Foreword By K. Sartor. Includes Bibliographical References And Index.