Morphogenesis and Evolution

Today developmental and evolutionary biologists are focussing renewed attention on the developmental process--those genetic and cellular factors that influence variation in individual body shape or metabolism--in an attempt to better understand how evolutionary trends and patterns within individuals might be limited and controlled. In this important work, the author reviews the classical literature on embryology, morphogenesis, and paleontology, and presents recent genetic and molecular studies on development. The result is a unique perspective on a set of problems of fundamental importance to developmental and evolutionary biologists. An admirable job. . . .examines current concepts of morphogenesis, including pattern formation in limbs of control animals as well as mutants such as eudiplopodia, luxate, brachypod, and nanomely. His discussion of Waddington's 'canalized landscape' metaphor. . . is particularly cogent. . . .The bibliography, index, and references are complete, current, and comprehensive. Should be purchased by academic libraries as a thorough interdisciplinary discussion of an intensely interesting and emerging area. --Choice Views the regular appearance of morphological gaps as a phenomenon worthy of a causal explanation which goes beyond the negative evidence of the incompleteness of the fossil record. I believe that this message deserves a wide audience among all those readers interested in the modern expansion of evolutionary theory. --American Scientist Represents a serious attempt to grapple with the overall problem of the role of developmental mechanisms in evolution. It is a tightly condensed discourse on an extremelycomplicated topic, and it is well worth reading. --BioScience Thomson's presentation is often circumspect and above all lucid. He integrates classical ideas from morphology and paleontology with recent work in experimental embryology and, to a lesser extent, molecular genetics . . . . This concise introduction to the potential role of ontogeny in evolution deserves to be widely read. --Quarterly Review of Biology [The author] shows an elegant style of explanation . . . . He clearly gives the evolutionary biologist pertinent developmental data in a form that can be easily understood. --American Zoologist Contents......Page 8 1. Introduction......Page 12 2. Theory, Reduction, and Hierarchy......Page 17 3. Development: Pattern and Process......Page 27 4. Early Pattern Formation......Page 34 5. Example: Early Pattern Formation in Amphibia......Page 47 6. Later Pattern Formation: Morphogenesis......Page 56 7. Some General Properties of Morphogenetic Systems......Page 78 8. Patterns of Evolution......Page 106 9. Morphogenesis and Evolution......Page 129 References......Page 148 D......Page 160 L......Page 161 S......Page 162 Z......Page 163