اصول مولکولی پاتوژنز قارچی

Annotation provides a state–of–the–art review of medical mycology compiled by the leading researchers in the field;presents a selection of chapters covering immunological aspects of infection;captures the excitement of recently completed genome projects and their impact on the understanding of fungal biology and virulence;examines the recent advances in the development of fungal vaccines;features an in–depth analysis of the host–pathogen relationship Read more... Content: Fungal molecular pathogenesis : what can it do and why do we need it? / John R. Perfect and Arturo Casadevall -- Sex, MAT, and the evolution of fungal virulence / James A. Fraser and Joseph Heitman -- Postgenomic strategies for genetic analysis : insight from Saccharomyces cerevisiae and Candida albicans / Clarissa J. Nobile and Aaron P. Mitchell -- Candida albicans hypha formation and virulence / Paula Sundstrom -- The conversion from classical studies in fungal pathogenesis to the molecular era / Kyung J. Kwon-Chung and Brian L. Wickes -- Mating and parasexual genetics in Candida albicans / Mathew Miller and Alexander Johnson -- The mating-type locus and mating of Candida albicans and Candida glabrata / David R. Soll -- Evolution of human pathogenic fungi : phylogenies and species / John W. Taylor -- Establishment of cell identity in pathogenic fungi / Christina M. Hull -- Signal transduction in the interactions of fungal pathogens and mammalian hosts / Malcolm Whiteway and Catherine Bachewich -- Function and regulation of adhesin gene families in Saccharomyces cerevisiae, Candida albicans, and Candida glabrata / Irene Castaño, Alejandro de las Peñas, and Brendan P. Cormack. Fungal biofilms : agents of disease and drug resistance / Gordon Ramage, Mahmoud A. Ghannoum, and José L. López-Ribot -- Molecular basis of fungal adherence to endothelial and epithelial cells / Scott G. Filler, Donald C. Sheppard, and John E. Edwards, Jr. -- Molecular principles of antifungal drug resistance / Dominique Sanglard and Theodore C. White -- Heterologous hosts and the evolution and study of fungal pathogenesis / Eleftherios Mylonakis, Stephen B. Calderwood, and Frederick M. Ausubel -- Amoeba and slime mold: hosts of virulence evolution / Arturo Casadevall -- Aspergillus nidulans : a model for elucidation of Aspergillus fumigatus secondary metabolism / Nancy Keller -- Saccharomyces cerevisiae : an emerging and model pathogenic fungus / John H. McCusker -- Fungal-bacterial interactions / Deborah A. Hogan and Roberto Kolter -- Amphibian chytridiomycosis as an emerging infectious disease of wildlife : what can we learn from the earliest diverging fungi? / Timothy Y. James and Rytas Vilgalys -- Cryptococcus neoformans : a sugar-coated killer / John R. Perfect -- Toward a molecular understanding of Candida albicans virulence / Frank C. Odds, Neil A.R. Gow, and Alistair J.P. Brown -- Molecular determinants of Histoplasma capsulatum pathogenesis / Jon P. Woods -- Molecular determinants of virulence in Aspergillus fumigatus / Judith C. Rhodes and Axel A. Brakhage -- Pathogenesis of pneumocystis / A. George Smulian and Melanie T. Cushion. Virulence mechanisms of coccidioides / Garry T. Cole [and others] -- Blastomyces dermatitidis cell surface determinants and their application in vaccine development / Bruce Klein -- Virulence factors in black molds with emphasis on melanin, chitin, and Wangiella as a molecularly tractable model / Paul J. Szaniszlo -- Zygomycetes as agents of infectious disease in humans / Ashraf S. Ibrahim and Brad Spellberg -- Signaling pathways in the dimorphic human fungal pathogen Penicillium marneffei / Alex Andrianopoulos and Sophie Zuber -- Innate humoral immunity to fungi / Thomas R. Kozel -- Innate and acquired cellular immunity to fungi / Luigina Romani -- Acquired antibody-mediated immunity to fungi / Liise-anne Pirofski and Arturo Casadevall -- Site-specific mucosal immunity to fungi : lessons learned from Candida albicans applied to other fungi / Paul L. Fidel, Jr. and Beatriz Finkel-Jimenez -- Intracellular pathogenesis of Histoplasma capsulatum / Simon L. Newman -- Interactions of immune cells with the facultative intracellular pathogen Cryptococcus neoformans / Lauren E. Yauch and Stuart M. Levitz. Fungal interactions with leukocytes / Mairi C. Noverr [and others] -- Fungal vaccine development / Joshua D. Nosanchuk and George S. Deepe Jr. -- Molecular immunopathogenesis of innate host defense against chronic disseminated (hepatosplenic) candidiasis / Thomas J. Walsh [and others] -- Studying fungal virulence using genomics / Michael C. Lorenz -- Future of functional genomics of Histoplasma capsulatum / Anita Sil and Lena Hwang -- Functional genomic approaches to fungal pathogenesis, drug target validation, and antifungal drug discovery / Ainslie B. Parsons, Howard Bussey, and Charles Boone -- Genetic and proteomic analysis of fungal virulence / Jennifer K. Lodge and Michael C. Lorenz -- Genomic perspectives on the fungal kingdom / Jason E. Stajich and Fred S. Dietrich. Abstract: State-of-the-art review of the field of medical mycology resulting in a valuable reference for students, fellows, faculty, researchers, and clinicians. Read more...

molecular Principles Of Fungal Pathogenesis Presents Readers With An Up-to-date Compendium Of Research In The Field Of Medical Mycology. This New Volume Measures The Impact Of Genome Projects, Genetics, And Molecular Biology On The Understanding Of A Diverse Group Of Pathogenic Fungi And Explores The Potential Impact Of Vaccines And New Therapeutic Approaches To Treatment. It Will Serve As A Valuable Resource For Students, Fellows, Instructors, Researchers, Specialists, Clinicians, And Anyone Interested In The General Field Of Microbial Pathogenesis.

doody Review Services

reviewer:rebecca T. Horvat, Phd, D(abmm)(university Of Kansas Medical Center)
description:this Book Focuses Specifically On The Molecular Basis Of Fungal Pathogenesis, Bringing Together The Current Research In Pathogenic Fungi And Presenting It In An Organized, Systematic Fashion.
purpose:according To The Editors, This Book Is Intended To Provide State-of-the-art Molecular And Genetic Approaches To The Classic Study Of Fungal Pathogens. The Generation Of This Book Is A Result Of The Many Years Of Experience From The Molecular Mycology Course Taught At The Marine Biological Laboratories In Woods Hole, Massachusetts. It Is Intended To Set The Stage For The Next Generation Of Teaching, Research And Discovery.
audience:the Book Is Directed At Individuals With Research Interests In Fungal Pathogenesis. It Brings Together The Accomplishments That Have Occurred In This Field Over The Past Several Years.
features:the First Of The Book's Five Sections Is On General Principles And Covers Such Topics As The Mechanism Of Antifungal Agents And The Complicated Topic Of Fungal Mating. The Next Section Details Model Systems Used To Study Fungi Such As The Use Of Drosophila To Study Aspergillus And Galleria Mellonella Used To Study Candida Species. The Third Section Discusses Specific Human Pathogens Such As Cryptococcus Species And The Soil Fungi, Histoplasma Capsulatum. The Next Section Examines The Host Immune Response To Specific Pathogens. In The Final Section There Is Discussion Of Future Areas Of Research And Discovery.
assessment:this Is Unique. I Know Of No Other Reference That Details The Current Information And Research On Fungal Pathogens Like This Book Does. I Would Highly Recommend This Book For A Graduate Level Fungal Pathogenesis Course.

Annotation provides a state & ndash;of & ndash;the & ndash;art review of medical mycology compiled by the leading researchers in the field;presents a selection of chapters covering immunological aspects of infection;captures the excitement of recently completed genome projects and their impact on the understanding of fungal biology and virulence;examines the recent advances in the development of fungal vaccines;features an in & ndash;depth analysis of the host & ndash;pathogen relationship