Molecular Biology of Cancer: Translation to the Clinic (Volume 95) (Progress in Molecular Biology and Translational Science, Volume 95)

Advances in molecular biology over the last several decades are being steadily applied to our understanding of the molecular biology of cancer, and these advances in knowledge are being translated into the clinical practice of oncology. This volume explores some of the most exciting recent advances in basic research on the molecular biology of cancer and how this knowledge is leading to advances in the diagnosis, treatment, and prevention of cancer. * This series provides a forum for discussion of new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields Content: Chapter 1 - Introduction to the Molecular Biology of Cancer: Translation to the Clinic Pages 1-8 Raymond W. Ruddon, M.D., Ph.D. Chapter 2 - Molecular Biology and Anticancer Drug Discovery Pages 9-29 John S. Lazo Chapter 3 - Targeting Chemokine (C-C motif) Ligand 2 (CCL2) as an Example of Translation of Cancer Molecular Biology to the Clinic Pages 31-53 Jian Zhang, Lalit Patel, Kenneth J. Pienta Chapter 4 - Chromosomal Aberrations in Solid Tumors Pages 55-94 Arul M. Chinnaiyan, Nallasivam Palanisamy Chapter 5 - Circulating Tumor Cells Pages 95-112 Daniel F. Hayes, Jeffrey B. Smerage Chapter 6 - Stem Cells in Normal Development and Cancer Pages 113-158 Rosemarie Chirco D'Angelo, Max S. Wicha Chapter 7 - Bioinformatics and Systems Biology of Cancers Pages 159-191 Gilbert S. Omenn Chapter 8 - Progress in Cancer Nanotechnology Pages 193-236 Istvan J. Majoros, Brent B. Ward, Kyung-Hoon Lee, Seok Ki Choi, Baohua Huang, Andrzej Myc, James R. Baker Chapter 9 - Applications of Molecular Imaging Pages 237-298 Craig J. Galbán, Stefanie Galbán, Marcian E. Van Dort, Gary D. Luker, Mahaveer S. Bhojani, Alnawaz Rehemtulla, Brian D. Ross Chapter 10 - Cancer Epigenetics Pages 299-349 Wendell Weber Chapter 11 - Molecular Targets and Clinical Cancer Risk Reductive Interventions Pages 351-375 Madhuri Kakarala, Dean E. Brenner Preface Page xi R.W. Ruddon, Ann Arbor Contributors Pages ix-x Copyright Page iv Index Pages 377-386 Explores the advances in basic research on the molecular biology of cancer and how this knowledge is leading to advances in the diagnosis, treatment, and prevention of cancer. This title provides a forum for discussion of various discoveries, approaches, and ideas. It is suitable for researchers involved in molecular biology and related fields.