Molecular Basis of Nerve Activity : Proceedings of the International Symposium in Memory of David Nachmansohn (1899–1983). Berlin, Federal Republic of Germany, October 11–13, 1984

In der 1968 gegründeten Reihe erscheinen Monographien aus den Gebieten der Griechischen und Lateinischen Philologie sowie der Alten Geschichte. Die Bände weisen eine große Vielzahl von Themen auf: neben sprachlichen, textkritischen oder gattungsgeschichtlichen philologischen Untersuchungen stehen sozial-, politik-, finanz- und kulturgeschichtliche Arbeiten aus der Klassischen Antike und der Spätantike. Entscheidend für die Aufnahme ist die Qualität einer Arbeit; besonderen Wert legen die Herausgeber auf eine umfassende Heranziehung der einschlägigen Texte und Quellen und deren sorgfältige kritische Auswertung. PREFACE Symposium Guests of Honour Symposium activities ON DAVID NACHMANSOHN'S RELATIONSHIP TO BERLIN CONTENTS David Nachmansohn (1899-1983): a pioneer of neurochemistry I. THE MOTOR ENDPLATE AND PRESYNAPTIC MECHANISMS REMODELLING OF NEUROMUSCULAR JUNCTIONS DURING REPAIR OF MUSCLE FIBRES INTERMITTENT, CALCIUM INDEPENDENT RELEASE OF ACETYLCHOLINE FROM MOTOR NERVE TERMINALS PROSTAGLANDINS MEDIATE THE MUSCARINIC INHIBITION OF ACETYLCHOLINE RELEASE FROM TORPEDO NERVE TERMINALS MOLECULAR MECHANISMS UNDERLYING ACETYLCHOLINE RELEASE ADENOSINE-5'-TRIPHOSPHATE AT THE CHOLINERGIC SYNAPSE: A CO-TRANSMITTER? SOLUBILIZATION, AFFINITY LABELLING AND PURIFICATION OF THE DIHYDROPYRIDINE RECEPTOR OF THE VOLTAGE-DEPENDENT CALCIUM CHANNEL FROM RABBIT SKELETAL MUSCLE TRANSVERSE TUBULE MEMBRANES IS ATP A GENERAL MOLECULAR CONSTITUENT OF CHOLINERGIC SYNAPTIC VESICLES? SINGLE CHANNEL FORMATION OF COOPERATIVELY INTERACTING UNITS OF THE HIGHLY-PURIFIED Na-CHANNEL PROTEIN K + -CHANNELS IN RAT VENTRICULAR CELLS SHOW VOLTAGE-DEPENDENT OUTWARD RECTIFICATION AND NON-LINEAR VOLTAGE TO CURRENT RELATION A PURIFICATION PROCEDURE OF THE TETRODOTOXIN BINDING COMPONENT CONTAINED IN THE ELECTROPLAXES OF ELECTROPHORUS ELECTRICUS HIGH-YIELD SYNTHESIS OF A NEW Na-CHANNEL MARKER : ( 3 H)ETHYLENEDIAMINE DITETRODOTOXIN OR ED-diTTX INSECT OLFACTORY CELLS: ELECTROPHYSIOLOGICAL AND BIOCHEMICAL STUDIES EFFECTS OF EXTRACELLULAR ATP ON 86 Rb INFLUX IN CHICK MYOTUBES; INDICATIONS OF A COTRANSMITTER ROLE IN NEUROMUSCULAR TRANSMISSION II. THE ACETYLCHOLINE RECEPTOR: STRUCTURAL ASPECTS A MONOCLONAL ANTIBODY SPECIFIC FOR ONE OF THE TWO AGONIST BINDING SITES AT THE ACETYLCHOLINE RECEPTOR THE MOLECULAR BIOLOGY OF ACETYLCHOLINE RECEPTORS ANTIBODIES TO SYNTHETIC PEPTIDES AS PROBES OF NICOTINIC ACETYL-CHOLINE RECEPTOR STRUCTURE REGULATION OF THE NICOTINIC ACETYLCHOLINE RECEPTOR BY PHOSPHORYLATION MOLECULAR INTERACTIONS BETWEEN THE MAJOR PROTEINS OF THE POSTSYNAPTIC DOMAIN IN TORPEDO MARMORATA ELECTROMOTOR SYNAPSE THE GLYCINE RECEPTOR OF RAT SPINAL CORD: PROGRESS IN THE INVESTIGATION OF A NEURONAL ION CHANNEL PROTEIN ANTIBODIES TO SYNTHETIC PEPTIDES AS PROBES FOR THE a-SUBUNIT AND FOR THE CHOLINERGIC BINDING SITE OF THE ACETYLCHOLINE RECEPTOR POSTSYNAPTIC MODULATION OF NEURONAL FIRING PATTERN BY ADENOSINE MAJOR PROTEINS OF THE ELECTRIC ORGAN FROM TORPEDO MARMORATA - POSSIBLE ASSOCIATIONS WITH THE POSTSYNAPTIC MEMBRANE PROTEIN-BLOT ANALYSIS OF THE NICOTINIC ACETYLCHOLINE RECEPTOR III. THE ACETYLCHOLINE RECEPTOR: FUNCTIONAL ASPECTS ACETYLCHOLINE RECEPTOR (FROM ELECTROPIIORUS ELECTRICUS) : A COMPARISON OF SINGLE-CHANT JE], CUPREMT RECORDINGS A W CHE1TICAL KINETIC t'JEASURFMENTS PHOTOAFFINITY LABELING OF RECEPTOR STATES WITH MILLISECOND TIME RESOLUTION BINDING OF [ 3 H] ACETYLCHOLINE TO ACETYLCHOLINE RECEPTOR FROM TORPEDO CALIFORNICA UNDER EQUILIBRIUM CONDITIONS: STOICHIOMETRY AND EVIDENCE FOR LONG-LIVED METASTABLE STATES THE DIMER OF TORPEDO ACETYLCHOLINE RECEPTOR: SYNCHRONIZED DOUBLE CHANNEL SYNCHRONIZATION OF ELECTRICALLY AND CHEMICALLY EXCITABLE ION CHANNELS EFFECTS OF HISTRIONICOTOXIN ON THE SYNAPTIC AND CONDUCTING MEMBRANES OF THE ELECTROPLAX THIAMINE TRIPHOSPHATE AS SPECIFIC OPERATING SUBSTANCE IN AXONAL CONDUCTION DOSE RESPONSE CURVES AT THE NEUROMUSCULAR JUNCTION NBD-5-ACYLCHOLINE IS A FLUORESCENT AGONIST OF THE MEMBRANE-BOUND ACETYLCHOLINE RECEPTOR FROM TORPEDO MARMORATA DO SIGMOID DOSE-RESPONSE CURVES REQUIRE THE ASSUMPTION OF ALLOSTERICITY? FOUNDATIONS OF THE ION FLUX METHOD SURFACE PROCESSES IN ION TRANSPORT AND EXCITATION CHEMICAL KINETIC INVESTIGATIONS OF THE EFFECTS OF CIS AND TRANS BIS-Q CN THE ACETYLCHOLINE RECEPTOR IN ELECTROPHORUS ELECTRICUS VESICLES DETERMINATION OF THIAMINE AND ITS PHOSPHATE ESTERS BY REVERSED-PHASE HPLC AT FEMTOMOLE LEVELS. APPLICATION TO BIOELECTROGENESIS IV. IMMUNOLOGY OF THE ACETYLCHOLINE RECEPTOR: MYASTHENIA GRAVIS AND SYNAPTIC PLASTICITY REGULATION OF THE IMMUNE RESPONSE TO THE ACETYLCHOLINE RECEPTOR AND OF EXPERIMENTAL MYASTHENIA CONGENITAL AND AUTOIMMUNE DISEASES OF THE NEUROMUSCULAR JUNCTION ANTI-IDIOTYPIC ANTIBODY TO THE ACETYLCHOLINE AND ADENOSINE RECEPTORS ANALYSIS OF THE PROPHYLACTIC AND THERAPEUTIC ACTION OF ELEC1RCLECHN IN EXPERIMENTAL AUTOIMMUNE MYASTHENIA GRAVIS Regulation of Acetylcholine Receptors on Muscle in vitro by Central Nervous System Factors USE AND DISUSE AND THE CONTROL OF ACETYLCHOLINESTERASE ACTIVITY IN FAST AND SLOW TWITCH MUSCLE OF RAT THE EXPRESSION OF MICROTUBULE PROTEINS DURING THE DEVELOPMENT OF THE NERVOUS SYSTEM V. ACETYLCHOLINESTERASE AND CHOLINE ACETYLTRANSFERASE ACETYLCHOLINESTERASE OF MUSCLE AND NERVE EXPRESSION OF ACETYLCHOLINESTERASE IN MURINE NEURAL CELLS IN VIVO AND IN CULTURE THE INVOLVEMENT OF PHOSPHATIDYLINOSITOL IN THE ANCHORING OF HYDROPHOBIC FORMS OF ACETYLCHOLINESTERASE TO THE PLASMA MEMBRANE THE HYDROPHOBIC DOMAIN OF HUMAN ERYTHROCYTE ACETYLCHOLINESTERASE CONTAINS NONAMINO ACID COMPONENTS CHOLINESTERASE: TWO SURPRISING INHIBITORS CORRELATION OF ASSUMED FUNCTIONS OF ACETYLCHOLINESTERASE WITH ITS CELLULAR AND SUBCELLULAR DISTRIBUTION THE MECHANISM OF ACTION OF CHOLINE ACETYLTRANSFERASE ACETYLCHOLINESTERASE IN REGENERATING SKELETAL MUSCLES Distribution and regulation of acetylcholinesterase forms in chick myotubes : comparison with rat myotubes ACETYLCHOLINESTERASE IN MAMMALIAN SKELETAL MUSCLE AND SYMPATHETIC GANGLION CELLS. EXTRA AND INTRACELLULAR HYDROPHILIC AND HYDROPHOBIC ASYMMETRIC FORMS INHIBITION AND PHOTOAFFINITY LABELING OF ACETYLCHOLINESTERASE BY PHENCYCLIDINE AND TRIPHENYLMETHYLPHOSPHONIUM A COMPARATIVE STUDY OF THE AGEING OF DFP-INHIBITED SERINE HYDROLASES BY MEANS OF 31 P-NMR AND MASS SPECTROMETRY LIPID MECHANISM AND ACETYLCHOLINESTERASE FUNCTION AUTHOR INDEX SUBJECT INDEX