Modern Hematology: Biology and Clinical Management (Contemporary Hematology)

In Modern Hematology: Biology and Clinical Management, Reinhold Munker and his distinguished colleagues offer a concise up-to-date summary of the fundamentals of clinical hematology, including all the most recent developments. Their comprehensive survey presents the essential clinical facts concerning malignant and nonmalignant blood diseases, detailing diagnostic methods, angiostatic drugs, the very latest therapies (e.g., stem cell transplantation), classifications, scientific controversies, and clear treatment recommendations. They also illuminate the scientific basis needed to understand the new diagnostic and treatment methodologies, the molecular pathogenesis of many hematologic disorders, and the new cellular therapies for these malignant disorders. All major blood diseases are covered, as well as the rarer disorders of special scientific interest. Modern Hematology: Biology and Clinical Management strikes an authoritative balance between clinical acumen and fundamental understanding. By concisely combining cutting-edge explanations of disease pathophysiology with practical approaches to the diagnosis and management of hematologic disorders, it provides an invaluable vade mecum for today's physicians and students needing to keep up with the latest clinical and scientific developments. Front Matter....Pages i-xi Basic Biology of Hemopoiesis....Pages 1-18 Molecular Biology and Cytokines....Pages 19-34 Supportive Care in Hematology....Pages 35-42 Transplantation of Stem Cells from Bone Marrow and Blood....Pages 43-60 Anemias: General Considerations and Microcytic and Megaloblastic Anemias ....Pages 61-75 Hemolytic Anemias....Pages 77-95 Leukocytosis, Leukopenia, and Other Changes of the Myeloid Series....Pages 97-104 The Myeloproliferative Syndromes....Pages 105-116 Acute Myelogenous Leukemias....Pages 117-129 Acute Lymphoblastic Leukemias....Pages 131-145 Myelodysplastic Syndromes....Pages 147-156 Aplastic Anemias....Pages 157-165 Lymphocytosis, Lymphocytopenia, Lymphadenopathy, and Splenomegaly....Pages 167-172 Hodgkin’s Disease....Pages 173-180 The Non-Hodgkin’s Lymphomas....Pages 181-208 Multiple Myeloma and Related Paraproteinemias....Pages 209-226 Congenital and Acquired Immunodeficiencies....Pages 227-236 Infections Relevant to Hematology....Pages 237-246 Basic Principles of Hemostasis....Pages 247-265 Bleeding Disorders....Pages 267-298 Thrombophilia, Thromboembolic Disease, and Antithrombotic Therapy....Pages 299-316 Transfusion Medicine and Hematology....Pages 317-332 Back Matter....Pages 333-369