Modern Amination Methods

Книга Modern Amination Methods Modern Amination MethodsКниги Химия Автор: Alfredo Ricci Год издания: 2000 Формат: pdf Издат.:Wiley-VCH Страниц: 285 Размер: 9,9 ISBN: 3527299769 Язык: Английский0 (голосов: 0) Оценка:Organic compounds containing amino groups are at the center of modern organic chemistry, and are widely used in the pharmaceutical industry, crop protection, natural product chemistry, and in advanced materials. Modern methods for the introduction of the amino group are therefore of major importance to synthetic chemists and product developers.Over the last decade, many methods have been developed to generate new C-N bonds. At the same time, the pharmaceutical and chemical industry was rapidly moving away from the development of racemic compounds to the direct synthesis of enantiomerically pure materials. The articles of this book, written by internationally recognized experts, thus focus on asymmetric synthesis.The most recent catalytic amination methods have particularly revolutionized the chemistry of amino compounds - and you find them all in this first comprehensive overview. Carbon-carbon bond forming reactions are arguably the most important processes in chemistry, as they represent key steps in the building of complex molecules from simple precursors. Among these reactions, metal-catalyzed cross-coupling reactions are extensively employed in a wide range of areas of preparative organic chemistry, ranging from the synthesis of complex natural products, to supramolecular chemistry, and materials science.
In this work, a dozen internationally renowned experts and leaders in the field bring the reader up to date by documenting and critically analyzing current developments and uses of metal-catalyzed cross-coupling reactions. A particularly attractive and useful feature, that enhances the practical value of this monograph, is the inclusion of key synthetic protocols, in experimental format, chosen for broad utility and application.
This practice-oriented book can offer the practitioner short cuts to ensure they remain up-to-date with the latest developments. Cover......Page 1 Modern Amination Methods......Page 2 Related Titles from WILEY-VCH......Page 3 Title......Page 4 Copyright......Page 5 Preface......Page 6 Contents......Page 9 Abbreviations......Page 15 List of Authors......Page 17 1 Modem Allylic Amination Methods......Page 19 2 Electrophilic Amination Routes from Alkenes......Page 54 3 Stereoselective Electrophilic Amination with Sulfonyloxycarbamates and Azodicarboxylates......Page 81 4 Glycosylamines as Auxiliaries in Stereoselective Syntheses of Chiral Amino Compounds......Page 119 5 Syntheses of Transition Metal Nitride Complexes......Page 145 6 Asymmetric Nitrogen Transfer with Nitridomanganese Complexes......Page 184 7 Palladium-Catalyzed Amination of Aryl Halides and Sulfonates......Page 210 Index......Page 278 Back Cover......Page 283 Organic compounds containing amino groups are at the center of modern organic chemistry, and are widely used in the pharmaceutical industry, crop protection, natural product chemistry, and in advanced materials. Modern methods for the introduction of the amino group are therefore of major importance to synthetic chemists and product developers. Over the last decade, many methods have been developed to generate new C-N bonds. At the same time, the pharmaceutical and chemical industry was rapidly moving away from the development of racemic compounds to the direct synthesis of enantiomerically pu 1. Modern allylic amination methods 2. Eletrophilic amination routes from alkenes 3. Stereoslective electrophilic amination with sulfonyloxycarbamates and axodicarboxylates 4. Glycosylamines as auxiliaries in stereoselective syntheses of chiral amino compounds 5. Syntheses of transition metal nitride complexes 6. Asymmetric nitrogen transfer with nitridomaganese complexes 7. Palladium-catalyzed amination of aryl halides and sulfonates. This is possibly the first book to offer an overview of the up-to-date and most effective amination methods. It collates the latest knowledge scattered around numerous journals, into one concise volume.