Modeling Momentum and Mass Transport in Cellular Biological Media: From the Molecular to the Tissue Scale

Transport in Biological Media is a solid resource of mathematical models for researchers across a broad range of scientific and engineering problems such as the effects of drug delivery, chemotherapy, or insulin intake to interpret transport experiments in areas of cutting edge biological research. A wide range of emerging theoretical and experimental mathematical methodologies are offered by biological topic to appeal to individual researchers to assist them in solving problems in their specific area of research. Researchers in biology, biophysics, biomathematics, chemistry, engineers and clinical fields specific to transport modeling will find this resource indispensible. Provides detailed mathematical model development to interpret experiments and provides current modeling practices Provides a wide range of biological and clinical applications Includes physiological descriptions of models Content: Transport in Biological Media , Page i Transport in Biological Media , Page iii Copyright , Page iv Preface , Pages xi-xiii Chapter 1 - Modeling Momentum and Mass Transport in Cellular Biological Media: From the Molecular to the Tissue Scale , Pages 1-40 , George E. Kapellos, Terpsichori S. Alexiou Chapter 2 - Thermal Pain in Teeth: Heat Transfer, Thermomechanics and Ion Transport , Pages 41-57 , Min Lin, ShaoBao Liu, Feng Xu, TianJian Lu, BoFeng Bai, Guy M. Genin Chapter 3 - Drug Release in Biological Tissues , Pages 59-118 , Filippo de Monte, Giuseppe Pontrelli, Sid Becker Chapter 4 - Transport of Water and Solutes Across Endothelial Barriers and Tumor Cell Adhesion in the Microcirculation , Pages 119-180 , Bingmei M. Fu, Yang Liu Chapter 5 - Carrier-Mediated Transport Through Biomembranes , Pages 181-212 , Ranjan K. Pradhan, Kalyan C. Vinnakota, Daniel A. Beard, Ranjan K. Dash Chapter 6 - Blood Flow Through Capillary Networks , Pages 213-252 , C. Pozrikidis, J.M. Davis Chapter 7 - Models of Cerebrovascular Perfusion , Pages 253-273 , T. David, R.G. Brown Chapter 8 - Mechanobiology of the Arterial Wall , Pages 275-347 , Anne M. Robertson, Paul N. Watton Chapter 9 - Shear Stress Variation and Plasma Viscosity Effect in Microcirculation , Pages 349-390 , Xuewen Yin, Junfeng Zhang Chapter 10 - Targeted Drug Delivery: Multifunctional Nanoparticles and Direct Micro-Drug Delivery to Tumors , Pages 391-416 , Clement Kleinstreuer, Emily Childress, Andrew Kennedy Chapter 11 - Electrotransport Across Membranes in Biological Media: Electrokinetic Theories and Applications in Drug Delivery , Pages 417-454 , S. Kevin Li, Jinsong Hao, Mark Liddell Chapter 12 - Mass Transfer Phenomena in Electroporation , Pages 455-492 , Alexander Golberg, Boris Rubinsky Chapter 13 - Modeling Cell Electroporation and Its Measurable Effects in Tissue , Pages 493-520 , Nataša Pavšelj, Damijan Miklavčič, Sid Becker Chapter 14 - Modeling Intracellular Transport in Neurons , Pages 521-549 , Andrey V. Kuznetsov Index , Pages 551-559 Transport in Biological Media offers a fundamental perspective of the current understanding of the physics underlying transport phenomena in biological media. The work discusses the modeling of thermal, ionic and molecular transport in living tissue and is directed towards an audience of academic and clinical researchers. It is the goal of this book to promote an understanding of the physics, the modeling, and the biological physiology in order to help bridge the gap between biology and transport modeling. Transport in Biological Media presents descriptions of parametric physiological influences that underlie the physics governing transport. In depth description, comparisons, and derivations of current mathematical modeling strategies are provided in applications of fluid dynamics, diffusion, and electrokinetic transport. This book of collected chapters is indispensable to researchers in biology, biophysics, biomathematics, chemistry, engineers and clinical fields specific to transport modeling. Key Features: Discusses in detail the multi-scale physics governing site-specific phenomena associated with transport in living tissue. Offers a clear understanding of the rationale behind the choice of a specific model. Provides a compendium of theoretical and analytical models in applications with specific chapters covering: drug delivery, electroporation, membrane science, transdermal delivery, active and passive transport in perfuse tissue, and transport across the endothelium. Book jacket

Transport in Biological Media is a solid resource of mathematical models for researchers across a broad range of scientific and engineering problems such as the effects of drug delivery, chemotherapy, or insulin intake to interpret transport experiments in areas of cutting edge biological research. A wide range of emerging theoretical and experimental mathematical methodologies are offered by biological topic to appeal to individual researchers to assist them in solving problems in their specific area of research. Researchers in biology, biophysics, biomathematics, chemistry, engineers and clinical fields specific to transport modeling will find this resource indispensible.

• Provides detailed mathematical model development to interpret experiments and provides current modeling practices
• Provides a wide range of biological and clinical applications
• Includes physiological descriptions of models