MODa 6 -- Advances in Model-Oriented Design and Analysis : Proceedings of the 6th International Workshop on Model-Oriented Design and Analysis held in Puchberg/Schneeberg, Austria, June 25-29, 2001

The volume contains the proceedings of the 6th Workshop on Model-Oriented Design and Analysis, within a series of workshops that initially had the purpose of bringing together leading scientists from Eastern and Western Europs for the exchange of ideas in theoretical and applied statistics, with special emphasis on experimental design. The participants of these workshops have developed into a community with a range of common interests that are centred around the theory and applications of optimum design of experiments. In addition to this, the volume contains a series of special papers on topics from medical and pharmaceutical statistics. Front Matter....Pages i-xv Trend-free Repeated Measurement Designs....Pages 1-12 Minimax Optimal Designs for Nonparametric Regression — A Further Optimality Property of the Uniform Distribution....Pages 13-20 Optimization of Monitoring Networks for Estimation of the Semivariance Function....Pages 21-28 A-optimal Chemical Balance Weighing Designs with Diagonal Covariance Matrix of Errors....Pages 29-36 Replications with Gröbner Bases....Pages 37-44 Extracting Information from the Variance Function: Optimal Design....Pages 45-52 Model Validity Range in Multicentre Clinical Trials....Pages 53-61 Two Models of Nonadaptive Group Testing for Designing Screening Experiments....Pages 63-75 Optimal Designs for a Continuation-ratio Model....Pages 77-85 Bayesian Interpolation Schemes for Monitoring Systems....Pages 87-95 Optimality of the Wald SPRT for Processes with Continuous Time Parameter....Pages 97-110 Efficient Paired Comparison Designs for Utility Elicitation....Pages 111-118 Optimal Design for the Testing of Anti-malarial Drugs....Pages 119-126 Optimal Adaptive Designs for Delayed Response Models: Exponential Case....Pages 127-134 Non- D -optimality of the Simplex Centroid Design for Regression Models Homogeneous of Degree p ....Pages 135-142 New Upper Bounds for Maximum-Entropy Sampling....Pages 143-153 Residuals....Pages 155-162 Asymptotically Optimal Sequential Discrimination between Markov Chains....Pages 163-170 Optimum Experimental Designs for a Modified Inverse Linear Model....Pages 171-181 Permutation Tests for Effects in Unbalanced Repeated Measures Factorial Designs....Pages 183-191 The Influence of the Design on the Breakdown Point of l 1 -type M-estimators....Pages 193-200 Analytical Properties of Locally D -optimal Designs for Rational Models....Pages 201-209 Understanding Aliasing Using Gröbner Bases....Pages 211-216 Average D -optimum Design for Randomly Varying Experimental Conditions....Pages 217-224 Constrained Bayesian Optimal Designs for Phase I Clinical Trials: Continuous Dose Space....Pages 225-233 Trend-Robust and Budget Constrained Optimum Designs....Pages 235-242 Minimax Designs for Logistic Regression in a Compact Interval....Pages 243-250 Sensor Motion Planning with Design Criteria in Output Space....Pages 251-258 Quality Improvement of Signal-Dependent Systems....Pages 259-266 Recursive Algorithm for Digital Diffusion Networks and Applications to Image Processing....Pages 267-275 Back Matter....Pages 277-283 This book includes many of the papers presented at the 6th International workshop on Model Oriented Data Analysis held in June 2001. This series began in March 1987 with a meeting on the Wartburg near Eisenach (at that time in the GDR). The next four meetings were in 1990 (St Kyrik monastery, Bulgaria), 1992 (Petrodvorets, St Petersburg, Russia), 1995 (Spetses, Greece) and 1998 (Marseilles, France). Initially the main purpose of these workshops was to bring together leading scientists from 'Eastern' and 'Western' Europe for the exchange of ideas in theoretical and applied statistics, with special emphasis on experimental design. Now that the sep­ aration between East and West is much less rigid, this exchange has, in principle, become much easier. However, it is still important to provide opportunities for this interaction. MODA meetings are celebrated for their friendly atmosphere. Indeed, dis­ cussions between young and senior scientists at these meetings have resulted in several fruitful long-term collaborations. This intellectually stimulating atmosphere is achieved by limiting the number of participants to around eighty, by the choice of a location in which communal living is encour­ aged and, of course, through the careful scientific direction provided by the Programme Committee. It is a tradition of these meetings to provide low cost accommodation, low fees and financial support for the travel of young and Eastern participants. This is only possible through the help of sponsors and outside financial support was again important for the success of the meeting.

the Volume Contains The Proceedings Of The 6th Workshop On Model-oriented Design And Analysis, Within A Series Of Workshops That Initially Had The Purpose Of Bringing Together Leading Scientists From Eastern And Western Europe For The Exchange Of Ideas In Theoretical And Applied Statistics, With Special Emphasis On Experimental Design. The Participants Of These Workshops Have Developed Into A Community With A Range Of Common Interests That Are Centred Around The Theory And Applications Of Optimum Design Of Experiments. In Addition To This, The Volume Contains A Series Of Special Papers On Topics From Medical And Pharmaceutical Statistics.

In many industrial, medical and agricultural experiments, treatments are applied to each experimental unit sequentially in time or space.