Microbial Endocrinology: Interkingdom Signaling in Infectious Disease and Health (Advances in Experimental Medicine and Biology Book 874)

This new edition highlights the numerous advances made in the field of microbial endocrinology over the last five years. Prominent among these new topics featured is the emergence of the microbiota-gut-brain axis and the role it plays in brain function. Specific focus is given to the role of microbial endocrinology in the evolutionary symbiosis between man and microbe as it relates to both health and disease. With new chapters on the microbiome and its relation to neurochemicals, this new edition brings this important volume up to date. Front Matter....Pages i-xiii Microbial Endocrinology: An Ongoing Personal Journey....Pages 1-24 New Trends and Perspectives in the Evolution of Neurotransmitters in Microbial, Plant, and Animal Cells....Pages 25-77 Catecholamine-Directed Epithelial Cell Interactions with Bacteria in the Intestinal Mucosa....Pages 79-99 Dietary Catechols and their Relationship to Microbial Endocrinology....Pages 101-119 Interactions Between Bacteria and the Gut Mucosa: Do Enteric Neurotransmitters Acting on the Mucosal Epithelium Influence Intestinal Colonization or Infection?....Pages 121-141 Modulation of the Interaction of Enteric Bacteria with Intestinal Mucosa by Stress-Related Catecholamines....Pages 143-166 Molecular Profiling: Catecholamine Modulation of Gene Expression in Escherichia coli O157:H7 and Salmonella enterica Serovar Typhimurium....Pages 167-182 Staphylococci, Catecholamine Inotropes and Hospital-Acquired Infections....Pages 183-199 Interkingdom Chemical Signaling in Enterohemorrhagic Escherichia coli O157:H7....Pages 201-213 Mechanisms of Stress-Mediated Modulation of Upper and Lower Respiratory Tract Infections....Pages 215-223 Psychological Stress, Immunity, and the Effects on Indigenous Microflora....Pages 225-246 The Epinephrine/Norepinephrine /Autoinducer-3 Interkingdom Signaling System in Escherichia coli O157:H7....Pages 247-261 The Role of the Microbiome in the Relationship of Asthma and Affective Disorders....Pages 263-288 Effects of Stress on Commensal Microbes and Immune System Activity....Pages 289-300 Microbiome to Brain: Unravelling the Multidirectional Axes of Communication....Pages 301-336 Mycologic Endocrinology....Pages 337-363 Back Matter....Pages 365-374 "Microbial endocrinology represents a newly emerging interdisciplinary field that is formed by the intersection of the fields of neurobiology and microbiology. It is the intent of this book to introduce a new perspective to the current understanding not only of the factors that mediate the ability of microbes to cause disease, but also to the mechanisms that maintain normal homeostasis. The discovery that microbes can both synthesize and directly respond to neuroendocrine hormones provides for a new framework with which to investigate how microorganisms interface not only with vertebrates, but also with invertebrates and even plants. The reader will learn that neuroendocrine hormones, most commonly associated with mammals, are actually found throughout the plant, insect and microbial kingdoms to an extent that will undoubtedly surprise many, and most importantly, highlight how interactions between microbes and neuroendocrine hormones influence health and the pathophysiology of infectious disease. This book will lead its readers to the understanding that through eons of association with eukaryotic organisms, bacteria have evolved specific detection systems for neuroendocrine hormones, which they utilize not only to "sense" their environment, but also to co-op products of neurophysiological responses for their own survival"--Publisher's description "The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host ("us"). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease"--