Micro Total Analysis Systems : Proceedings of the ΜTAS ’94 Workshop, Held at MESA Research Institute, University of Twente, The Netherlands, 21–22 November 1994

The MESA Research Institute of the University of Twente was created in 1990 through the joining of the research unit Sensors and Actuators with the department of Microelectronics. The multidisciplinary institute, with participation from the faculties of Electrical Engineering, Applied Physics and Chemical Technology, was recently recognized as a Centre of Excellence by the Dutch Science Foundation. It is fully 2 equipped with modem Clean Room facilities (1000 m ) and a number of research laboratories. The objective of MESA is to perform research and development of systems in modem information technology, and on the units on which they are based: the microstructures that process and transduce signals. The institute gradually expanded during the past few years till some 125 persons in 1994. Given the wide variety of research subjects within MESA, it has been decided to start a MESA Monographs series, appearing on a more or less regular, yearly basis. In this way, after some time a good overview of research topics under investigation at MESA will be obtained. The first volume of this series coincides with the Proceedings of pTAS '94, the first Workshop on Micro Total Analysis Systems, held on November 21-22 at the University of Twente in Enschede, The Netherlands. IlTAS has recently been defined as the first strategic research orientation of MESA, aiming at synergetic collaboration between the different disciplines present in MESA. Front Matter....Pages i-x The Challenge of Developing μTAS....Pages 1-4 μ-TAS: Miniaturized Total Chemical Analysis Systems....Pages 5-27 Chances of μTAS in Analytical Chemistry....Pages 29-35 μTAS for Biochemical Analysis....Pages 37-46 Detection Principles for μ-TAS....Pages 47-70 Microfabricated Liquid Handling Elements....Pages 71-72 Micromechanical Components for μTAS....Pages 73-83 Material Science for Future (Bio-)Chemical Microsystems: The Key Role of Tailoring Interfaces....Pages 85-93 Optical Microsystems for (Bio)Chemical Analysis....Pages 95-103 Integration of Analytical Systems Incorporating Chemical Reactions and Electrophoretic Separation....Pages 105-115 Flow Injection Microsystems — There is a Past but Where is the Future ?....Pages 117-125 Micromachined Flow-Through Measurement Chambers Using LAPS Chemical Sensors....Pages 127-138 Development of a PCR-Microreactor....Pages 139-139 Application of Miniature Analyzers: from Microfluidic Components to μTAS....Pages 141-151 Microanalysis Systems for Gases....Pages 153-163 Bonding and Assembling Methods for Realising a μTAS....Pages 165-179 Microsystems for Analysis in Flowing Solutions....Pages 181-190 Combined Blood Gas Sensor for pO 2 , pCO 2 and pH....Pages 191-194 A Fluid Handling and Injection Microsystem for a μTAS....Pages 195-198 Design of an Adaptive Unsupervised Hybrid Microsystem for Artificial Olfaction....Pages 199-202 Integration of an Amperometric Glucose Sensor in a μ-TAS....Pages 203-207 Electric Field Mediated Cell Manipulation,Characterisation and Cultivation in Highly Conductive Media....Pages 209-214 Electrochemical Microanalytical System for Ionometric Measurements....Pages 215-218 Modular Potentiometric Measuring System for the Development and Comfortable Testing of Miniaturized Ion Sensors....Pages 219-222 A Novel Sampling Technique for Total Analysis Systems....Pages 223-226 A Micromachined Glucose Oxidase Enzyme Reactor....Pages 227-231 First Steps of μTAS in Latvia....Pages 233-236 Microreactor with Integrated Static Mixer and Analysis System....Pages 237-243 Microelectrode Arrays as Transducers for Microanalysis Systems....Pages 245-248 A Stacked Multichannel Amperometric Detection System....Pages 249-254 Components for Microfluidic Handling Modules....Pages 255-258 Development of a Micro Flow-System with Integrated Biosensor Array....Pages 259-262 Temperature Controller for μTAS Applications....Pages 263-266 Redox-Sensitive Field-Effect Transistors as Transducers for Micro-Analysis Systems....Pages 267-271 Performance of the Coulometric Sensor-Actuator Device Improved by μTAS....Pages 273-277 Concept of a Miniaturised System for Multicomponent Gas Analysis Based on Non-Dispersive Infrared Techniques....Pages 279-282 A Double Chemfet Flow Cell System for Detection of Heavy Metal Ions and Integration in μTAS....Pages 283-288 Components and Technology for a Fluidic-Isfet-Microsystem....Pages 289-293 An On-Chip Miniature Liquid Chromatography System: Design, Construction and Characterization....Pages 295-298 A Microsystem Mass Spectrometer....Pages 299-304 Back Matter....Pages 305-311 Proceedings of the muTAS '94 Workshop, held at MESA Research Institute, University of Twente, the Netherlands, 21--22 November 1994