Methods of Cancer Diagnosis, Therapy, and Prognosis: Brain Cancer (Methods of Cancer Diagnosis, Therapy and Prognosis, Volume 8)

This eighth volume in the series Methods of Cancer Diagnosis, Therapy, and Prognosis discusses in detail the classification of the CNS tumors as well as brain tumor imaging. Scientists and Clinicians have contributed state of the art chapters on their respective areas of expertise, providing the reader a whole field view of the CNS tumors and brain tumor imaging in Europe. This fully illustrated volume: Explains the genetics of malignant brain tumors and gene amplification using quantitative-PCR; Presents a large number of standard and new imaging modalities, including magnetic resonance imaging, functional magnetic resonance imaging, diffusion tensor imaging, amide proton transfer imaging, positron emission tomography, single photon emission computed tomography, magnetic resonance single voxel spectroscopy and intraoperative ultrasound imaging, for staging and diagnosing various primary and secondary brain cancers; Explains the usefulness of imaging methods for planning and monitoring (assessment) therapy for cancers; Discusses diagnosis and treatment of primary CNS lymphomas, CNS atypical teratoid/rhabdoid and CNS Rosai-Dorfman disease; Includes the subject of translational medicine. Professor Hayat has summarized the problems associated with the complexities of research publications and has been successful in editing a must-read volume for oncologists, cancer researchers, medical teachers and students of cancer biology. Front Matter....Pages i-xlvi The World Health Organization Classification of the Central Nervous System Tumors: An Update Using Imaging....Pages 1-7 Brain Tumor Imaging: European Association of Nuclear Medicine Procedure Guidelines....Pages 9-19 Assessment of Heterogeneity in Malignant Brain Tumors....Pages 21-32 Diagnosing and Grading of Brain Tumors: Immunohistochemistry....Pages 33-51 Malignant Brain Tumors: Roles of Aquaporins....Pages 53-64 Brain Metastases: Gene Amplification Using Quantitative Real-Time Polymerase Chain Reaction Analysis....Pages 65-69 Cyclic AMP Phosphodiesterase-4 in Brain Tumor Biology: Immunochemical Analysis....Pages 71-82 Radiosurgical Treatment of Progressive Malignant Brain Tumors....Pages 83-96 Anti-vascular Therapy for Brain Tumors....Pages 97-108 Glial Brain Tumors: Antiangiogenic Therapy....Pages 109-119 Brain Tumors: Amide Proton Transfer Imaging....Pages 121-129 Diffusion Tensor Imaging in Rat Models of Invasive Brain Tumors....Pages 131-144 Brain Tumors: Diffusion Imaging and Diffusion Tensor Imaging....Pages 145-156 Brain Tumors: Planning and Monitoring Therapy with Positron Emission Tomography....Pages 157-178 Clinical Evaluation of Primary Brain Tumor: O-(2-[ 18 F]Fluorethyl)-L-Tyrosine Positron Emission Tomography....Pages 179-188 Combined Use of [F-18]Fluorodeoxyglucose and [C-11]Methionine in 45 PET-Guided Stereotactic Brain Biopsies....Pages 189-201 Hemorrhagic Brain Neoplasm – 99m Tc-Methoxyisobutyl Isonitrile-Single Photon Emission Computed Tomography....Pages 203-213 Brain Tumor Imaging Using p-[ 123 I]Iodo-L-Phenylalanine and SPECT....Pages 215-226 Diagnosis and Staging of Brain Tumours: Magnetic Resonance Single Voxel Spectra....Pages 227-243 Parallel Magnetic Resonance Imaging Acquisition and Reconstruction: Application to Functional and Spectroscopic Imaging in Human Brain....Pages 245-262 Intra-axial Brain Tumors: Diagnostic Magnetic Resonance Imaging....Pages 263-278 Brain Tumors: Apparent Diffusion Coefficient at Magnetic Resonance Imaging....Pages 279-296 Magnetic Resonance Imaging of Brain Tumors Using Iron Oxide Nanoparticles....Pages 297-304 Metastatic Solitary Malignant Brain Tumor: Magnetic Resonance Imaging....Pages 305-323 Brain Tumor Resection: Intra-operative Ultrasound Imaging....Pages 325-335 Primary Central Nervous System Lymphomas: Salvage Treatment....Pages 337-351 Central Nervous System Atypical Teratoid/Rhabdoid Tumors: Role of Insulin-Like Growth Factor I Receptor....Pages 353-364 Central Nervous System Rosai–Dorfman Disease....Pages 365-373 Back Matter....Pages 375-392