Metathesis in natural product synthesis : strategies, substrates and catalysts

Emphasizing the impact of metathesis in natural product synthesis through the different types of key reactions, this ready reference is clearly structured and packed with important information, including representative experimental procedures for practical applications. Content: Synthesis of Natural Products Containing Medium-Size Carbocycles by Ring-Closing Alkene Metathesis / Nicolas Blanchard, Jacques Eustache -- Natural Products Containing Medium-Sized Nitrogen Heterocycles Synthesized by Ring-Closing Alkene Metathesis / Sebastiaan (Bas) A M W van den Broek, Silvie A Meeuwissen, Floris L van Delft, Floris P J T Rutjes -- Synthesis of Natural Products Containing Medium-Size Oxygen Heterocycles by Ring-Closing Alkene Metathesis / Jon D Rainier -- Phosphorus and Sulfur Heterocycles via Ring-closing Metathesis: Application in Natural Product Synthesis / Christopher D Thomas, Paul R Hanson -- Synthesis of Natural Products Containing Macrocycles by Alkene Ring-Closing Metathesis / Ana Gradillas, Javier P̌rez-Castells -- Synthesis of Natural Products and Related Compounds Using Ene6Yne Metathesis / Miwako Mori -- Ring-Closing Alkyne Metathesis in Natural Product Synthesis / Paul W Davies -- Temporary Silicon6Tethered Ring6Closing Metathesis Reactions in Natural Product Synthesis / P Andrew Evans -- Metathesis Involving a Relay and Applications in Natural Product Synthesis / Thomas R Hoye, Junha Jeon -- Cross-Metathesis in Natural Products Synthesis / Jo︠lle Prunet, Laurence Grimaud -- Cascade Metathesis in Natural Product Synthesis / Marta Porta, Siegfried Blechert -- Catalytic Enantioselective Olefin Metathesis and Natural Product Synthesis / Amir H Hoveyda, Steven J Malcolmson, Simon J Meek, Adil R Zhugralin -- Metathesis Reactions in Solid-Phase Organic Synthesis / Sofia Barluenga, Pierre-Yves Dakas, Rajamalleswaramma Jogireddy, Ga︠le Valot, Nicolas Winssinger. Abstract: Emphasizing the impact of metathesis in natural product synthesis through the different types of key reactions, this clearly structured reference offers a comprehensive view of the topic. Packed with important information, including representative experimental procedures. Read more... Cover......Page 1 Front Matter......Page 2 Contents......Page 6 Foreword......Page 14 Preface......Page 15 List of Catalysts......Page 18 List of Contributors......Page 19 Abbreviations......Page 23 1. Synthesis of Natural Products Containing Medium-size Carbocycles by Ring-closing Alkene Metathesis......Page 26 2. Natural Products Containing Medium-sized Nitrogen Heterocycles Synthesized by Ring-closing Alkene Metathesis......Page 69 3. Synthesis of Natural Products Containing Medium-size Oxygen Heterocycles by Ring-closing Alkene Metathesis......Page 110 4. Phosphorus and Sulfur Heterocycles via Ring-closing Metathesis: Application in Natural Product Synthesis......Page 151 5. Synthesis of Natural Products Containing Macrocycles by Alkene Ring-closing Metathesis......Page 170 6. Synthesis of Natural Products and Related Compounds Using Ene-Yne Metathesis......Page 204 7. Ring-closing Alkyne Metathesis in Natural Product Synthesis......Page 226 8. Temporary Silicon-Tethered Ring-Closing Metathesis Reactions in Natural Product Synthesis......Page 245 9. Metathesis Involving a Relay and Applications in Natural Product Synthesis......Page 280 10. Cross-metathesis in Natural Products Synthesis......Page 305 11. Cascade Metathesis in Natural Product Synthesis......Page 331 12. Catalytic Enantioselective Olefin Metathesis and Natural Product Synthesis......Page 360 13. Metathesis Reactions in Solid-phase Organic Synthesis......Page 366 Index......Page 390 Emphasizing the impact of metathesis in natural product synthesis through the different types of key reactions, this is a comprehensive view of a hot topic. Written by top international authors, this ready reference is clearly structured and packed with important information, including representative experimental procedures for practical applications. A real must-have for anyone working in natural product synthesis.