Metal Ions in Life Sciences : Metal-carbon Bonds in Enzymes and Cofactors

[Download single chapters here!](http://www.degruyter.com/viewbooktoc/product/461945) The occurrence of a wide variety of metal-carbon bonds in living organisms, ranging from bacteria to humans, is only recently recognized. Of course, the historical examples are the B12 coenzymes containing cobalt-carbon bonds, but now such bonds are also known for nickel, iron, copper, and other transition metal ions. There is no other comparable book; MILS-6, written by 17 experts, summarizes the most recent insights into this fascinating topic. * Single chapters can be purchased. Organometallic chemistry of B12 coenzymes Cobalamin- and corrinoid-dependent enzymes Nickel-alkyl bond formation in the active site of methyl-coenzyme M reductase Nickel-carbon bonds in acetyl-coenzyme a synthases/carbon monoxide dehydrogenases Structure and function of [NiFe]-hydro-genases Carbon monoxide and cyanide ligands in the active site of [FeFe]-hydrogenases Carbon monoxide as intrinsic ligand to iron in the active site of [Fe]-hydrogenase Dual role of heme as cofactor and substrate in the biosynthesis of carbon monoxide Copper-carbon bonds in mechanistic and structural probing of proteins as well as in situations where copper is a catalytic or receptor site Interaction of cyanide with enzymes containing vanadium, manganese, non-heme iron, and zinc Reaction mechanism of the molybdenum hydroxylase xanthine oxidoreductase: evidence against the formation of intermediates having metal-carbon bonds. (http://www.degruyter.com/viewbooktoc/product/461945) Download single chapters here! The occurrence of a wide variety of metal-carbon bonds in living organisms, ranging from bacteria to humans, is only recently recognized. Of course, the historical examples are the B12 coenzymes containing cobalt-carbon bonds, but now such bonds are also known for nickel, iron, copper, and other transition metal ions. There is no other comparable book; MILS-6, written by 17 experts, summarizes the most recent insights into this fascinating topic. Single chapters can be purchased.

The occurrence of a wide variety of metal-carbon bonds in living organisms, ranging from bacteria to humans, is only recently recognized. Of course, the historical examples are the B12 coenzymes containing cobalt-carbon bonds, but now such bonds are also known for nickel, iron, copper, and other transition metal ions. There is no other comparable book; MILS-6, written by 17 experts, summarizes the most recent insights into this fascinating topic.

Metal Ions in Life Sciences links coordination chemistry and biochemistry in their widest sense and thus increases our understanding of the relationship between the chemistry of metals and life processes; in fact, it is an old wisdom that metals are indispensable for life. The series reflects the interdisciplinary nature of Biological Inorganic Chemistry and coordinates the efforts of scientists in numerous interconnecting research fields 9781847559159 i-iv v-vi vii-x xi-xvi xvii-xviii xix Ch001r Ch002r Ch003r CH004r CH005r CH006r CH007r CH008r Ch009r CH010r CH011r CH012r 461 497