Metabolic Syndrome Pathophysiology : The Role of Essential Fatty Acids

__Metabolic Syndrome Pathophysiology: The Role of Essential Fatty Acids__ provides current research exploring the links among insulin, insulin receptors, polyunsaturated fatty acids, brain growth and disease. Specific interactions of essential fatty acids and polyunsaturated fatty acids in brain development and several disease groups are described. The role of inflammation in disease and how fatty acids regulate low-systemic inflammation are examined and explained. Metabolic and neurologic dynamics are presented to provide a linkage between the presence of omega-3 and omega-6 and protection against diseases and conditions such as diabetes mellitus, obesity, autoimmune diseases and hypertension.Content: Chapter 1 Introduction (pages 1–3): Chapter 2 History, Definition, and Diagnosis of the Metabolic Syndrome (pages 4–12): Chapter 3 Insulin Resistance in the Metabolic Syndrome (pages 13–21): Chapter 4 Is It Necessary to Redefine the Metabolic Syndrome? (pages 22–25): Chapter 5 Is Insulin Resistance a Disorder of the Brain? (pages 26–42): Chapter 6 Obesity (pages 43–73): Chapter 7 Perinatal Nutrition and Obesity (pages 74–85): Chapter 8 Essential Hypertension (pages 86–104): Chapter 9 Dietary Factors and Hypertension (pages 105–112): Chapter 10 Is Hypertension a Disorder of the Brain? (pages 113–121): Chapter 11 Type 2 Diabetes Mellitus (pages 122–129): Chapter 12 Pathophysiology of Type 2 Diabetes Mellitus with Particular Reference to Hypothalamus (pages 130–145): Chapter 13 Insulin and Insulin Receptors in the Brain and Their Role in the Pathogenesis of Obesity and Type 2 Diabetes Mellitus (pages 146–155): Chapter 14 Insulin, Endothelial Nitric Oxide, and the Metabolic Syndrome (pages 156–166): Chapter 15 Obesity, Type 2 Diabetes Mellitus, the Metabolic Syndrome, and the Gut Microbiota (pages 167–176): Chapter 16 Is It Possible That the Metabolic Syndrome Originates in the Perinatal Period? (pages 177–180): Chapter 17 Essential Fatty Acids: Biochemistry and Physiology (pages 181–200): Chapter 18 Role of EFAs/PUFAs in Brain Growth and Development and Pathophysiology of the Metabolic Syndrome (pages 201–239): Chapter 19 EFAs/PUFAs and Their Metabolites in Insulin Resistance (pages 240–251): Chapter 20 EFAs/PUFAs and Atherosclerosis (pages 252–264):

Metabolic Syndrome Pathophysiology: The Role of Essential Fatty Acids

Metabolic Syndrome Pathophysiology: The Role of Essential Fatty Acids provides current research exploring the links among insulin, insulin receptors, polyunsaturated fatty acids, brain growth and disease. Specific interactions of essential fatty acids and polyunsaturated fatty acids in brain development and several disease groups are described. The role of inflammation in disease and how fatty acids regulate low-systemic inflammation are examined and explained. Metabolic and neurologic dynamics are presented to provide a linkage between the presence of omega-3 and omega-6 and protection against diseases and conditions such as diabetes mellitus, obesity, autoimmune diseases and hypertension.

Preliminary chapters provide an overview of the history and diagnosis of metabolic syndrome and its link to insulin resistance. Following chapters cover obesity, hypertension and diabetes, and remaining chapters provide detailed information on the role and physiology of essential fatty acids.

This book is a key reference for nutrition researchers and clinical nutritionists working in the areas of lipids and metabolism, metabolic syndrome, obesity, hypertension and diabetes.

• Comprehensively reviews current research on metabolic diseases

• Discusses molecular aspects of biochemistry, physiology, and pathology of metabolism of essential fatty acids

• Includes chapters devoted to obesity, hypertension, heart disease and certain cancers

History, definition and diagnosis of the metabolic syndrome -- Insulin resistance in the metabolic syndrome -- Is it necessary to redefine the metabolic syndrome? -- Is insulin resistance a disorder of the brain? -- Obesity -- Perinatal nutrition and obesity -- Essential hypertension -- Dietary factors and hypertension -- Is hypertension a disorder of the brain? -- Type 2 diabetes mellitus -- Pathophysiology of type 2 diabetes mellitus with particular reference to hypothalamus -- Insulin and insulin receptors in the brain and their role in the pathogenesis of obesity and type 2 diabetes mellitus -- Insulin, endothelial nitric oxide and the metabolic syndrome -- Obesity, type 2 diabetes mellitus and the metabolic syndrome and the gut microbiota -- Is it possible that the metabolic syndrome originates in the perinatal period? -- Essential fatty acids : biochemistry and physiology -- Role of EFAs/PUFAs in brain growth and development and pathophysiology of the metabolic syndrome -- EFAs/PUFAs and their metabolites in insulin resistance -- EFAs/PUFAs and atherosclerosis