Metabolic adaptation to prolonged physical exercise: Proceedings of the second International Symposium on Biochemistry of Exercise, Magglingen, 1973 (Scientific ... Federal School of Physical Education ; 7)

The Proceedings of the Second International Symposium on Biochemistry of Exercise are centered on the effects of long lasting exercise and training. In the years following the first symposium which was held in Brussels in 1968, biochem­ istry of exercise has gained more importance in view of the increasing number of labora­ tories and scientific papers which are dealing with this field. From the topic of the first symposium - humoral modifications occurring during physical activity - our points of interest have been turned to a more limited area, namely long term exercise and training, It was important to investigate these subjects because everyone knows that in to-day's sport a good performance means hours of weekly or even daily training. Therefore, it was of considerable interest to stimulate discussions and to clarify ideas in this particular field of human activity. Our knowledge of biochemistry of exercise at the cellular level has highly progressed during the last five years. Researchers have focused their interests on the sequential uti­ lization of fuels, the adaptative responses of the enzyme machinery, the different types of muscle fibers. The topics of the Proceedings include: general subjects, metabolism of carbohydrates, lipids, and proteins, hormonal regulations, electrolytes, ultrastructure and fiber types of muscle, cellular enzymes. In the symposium, the current knowledge was summarized as an introductory lecture to each of these topics by prominent authors, namely: J. KEuL (Freiburg i. Br. ), M. ScHERRER (Bern), B. SAL TIN (Copenhagen), P. Front Matter....Pages 1-10 Front Matter....Pages 11-11 The Use of Fuels for Muscular Work....Pages 12-30 Muscle Metabolism During Long Lasting Exercise....Pages 31-42 Pulmonary Gas Exchange During Physical Exercise....Pages 43-55 Respiratory Influences on Acid-Base Status and Their Effects on O 2 Transport during Prolonged Muscular Work....Pages 56-64 Observations Upon the Rate-Limiting Role of Blood Flow in the Regulation of Respiration of Skeletal Muscle During Intermittent Exercise....Pages 65-69 The Behavior of Stress Acidosis During Ergometric Examinations....Pages 70-72 The Changes of Acid Base Balance during Interval Swimming Training in Trained and Untrained Men....Pages 73-77 The Influence of Exhaustive Efforts at High Altitude (2040m) on Serum Enzymes (CPK, CPK act., LDH, SGOT, SGPT) in Well Trained Athletes....Pages 78-84 Malignant Tumours as Causes of Death of Former Athletes....Pages 85-91 Front Matter....Pages 93-93 Adaptive Changes in Carbohydrate Metabolism With Exercise....Pages 94-100 Lactate Removal at Rest and During Exercise....Pages 101-105 Lactate Metabolism and Glucose Lactate Conversion in Prolonged Physical Exercise....Pages 106-112 Effect of Physical Training on the Rates of Lactate Turnover and Oxidation in Rats....Pages 113-118 Differences in Metabolic Alterations With Sprint Versus Endurance Interval Training Programs....Pages 119-126 Muscle Glycogen Stores and Capacity for Anaerobic Work....Pages 127-129 Muscle Glycogen Content and Lactate Uptake in Exercising Muscles....Pages 130-134 The Effects of Prolonged Direct Muscle Stimulation and Recovery on Biochemicals Associated with Glycolysis in Rat Skeletal Muscle....Pages 135-138 The Effects of Prolonged Direct Muscle Stimulation on Biochemicals Associated with the Malate-Aspartate Shuttle in Rat Skeletal Muscle....Pages 139-143 Splanchnic and Leg Metabolism of Glucose, Free Fatty Acids and Amino Acids during Prolonged Exercise in Man....Pages 144-153 Front Matter....Pages 155-155 Effects of Long Lasting Physical Exercise and Training on Lipid Metabolism....Pages 156-193 Front Matter....Pages 155-155 Effects of a Marathon Race on Blood Lipid Constituents in Younger and Older Athletes....Pages 194-200 Long-Term Training and Net Transport of Plasma Free Fatty Acids....Pages 201-203 Sympathetic Activity During Prolonged Physical Exercise in Dogs: Control of Energy Substrate Utilization....Pages 204-210 Front Matter....Pages 211-211 Effects of Long Lasting Physical Exercise and Training on Protein Metabolism....Pages 212-228 Creatine, Creatinine and CPK in the Serum of Athletes....Pages 229-231 Protein Metabolism During Two Hour Ergometer Exercise’....Pages 232-237 The Role of Plasma Proteins in the Control of Plasma Volume During Exercise and Dehydration in Long Distance Runners and Cyclists....Pages 238-244 Biochemical Changes with Marathon Running Observations on Post-Coronary Patients....Pages 245-252 Effect of Prolonged Physical Training on the Development of Connective Tissues in Growing Mice....Pages 253-261 Hydroxyproline Concentrations in Ligaments From Trained and Nontrained Rats....Pages 262-267 The Polarographic Properties of Serum Following Various Exertions and After an in Vitro Addition of Sulfur-Containing Substances....Pages 268-274 Front Matter....Pages 275-275 The Effects of Long Lasting Physical Exercise and Training on Hormonal Regulation....Pages 276-292 The Role of Sympathetic Nervous System in the Adaptation of Skeletal Muscles to Increased Activity....Pages 293-300 Endocrine Mechanisms of Exercise-Induced Fatty Acids Mobilization in Rats....Pages 301-307 Plasma Aldosterone (PA), Plasma Renin Activity (PRA) and Cortisol (PF) During Exercise....Pages 308-314 Low Pressure System and Blood Volume Regulating Hormones after Prolonged Exercise....Pages 315-321 Effect of Muscular Exercise on Day-Time Variations of Plasma Cortisol and Glucose....Pages 322-325 Evolution of the Sympathico-Adrenal Response to Exercise During Physical Training in the Rat....Pages 326-332 Some Hormonal Changes After Different Kinds of Motor Stress in Trained and Untrained Young Men....Pages 333-338 Front Matter....Pages 339-339 Changes in Electrolytes and Trace Elements During Long-Lasting Exercise....Pages 340-351 Front Matter....Pages 339-339 Muscle Glycogen and Electrolytes Following Exercise and Thermal Dehydration....Pages 352-360 Magnesium Metabolism During Prolonged Heavy Exercise....Pages 361-366 Serum and Erythrocyte Zinc Concentrations After Prolonged Heavy Exercise....Pages 367-370 Front Matter....Pages 371-371 Ultrastructural Adaptation of Skeletal Muscle to Prolonged Physical Exercise....Pages 372-383 Morphometry and Enzyme Activities in Skeletal Muscle From Middle-Aged Men After Training and From Alcoholics....Pages 384-389 Mitochondrial Distributions in Hearts of Male Rats as a Function of Long-Term Physical Training....Pages 390-396 Glycogen Depletion in Rat Skeletal Muscle Fibers During Exercise....Pages 397-401 Glycogen Depletion in Specific Types of Human Skeletal Muscle Fibers in Intermittent and Continous Exercise....Pages 402-415 Glycogen Depletion Patterns in Human Skeletal Muscle Fibers after Varying Types and Intensities of Exercise....Pages 416-421 Glycogen Depletion Pattern in Human Muscle Fiber During Work under Curarization (d-Tubocurarine)....Pages 422-430 Effect of Exhaustive Exercise on the Rat Heart....Pages 431-435 Front Matter....Pages 437-437 Biochemical Adaptation of Skeletal Muscle to Prolonged Physical Exercise....Pages 439-447 Effect of Physical Training on Enzyme Activities of Bones, Tendons and Skeletal Muscles in Mice....Pages 448-450 The Effects of Exercise and Training on the Activities of Human Skeletal Muscle Glycogen Cycle Enzymes....Pages 451-462 Hexokinase (HK), Glyceraldehyde-3 P-Dehydrogenase (GAPDH), Succinate-Dehydrogenase (SDH), and 3-Hydroxyacyl-CoA-Dehydrogenase (HAD) in Skeletal Muscle of Trained and Untrained Men....Pages 463-465 The Effect of Prolonged Direct Electrical Stimulation upon the Enzymes of Fatty Acid Activation, Transport and Oxidation in Rat Skeletal Muscle....Pages 466-470 Metabolic Changes in Long-Term Stimulated Fast Muscles....Pages 471-475 Round Table and Panel Discussion....Pages 476-482 Back Matter....Pages 483-489 The Proceedings of the Second International Symposium on Biochemistry of Exercise are centered on the effects of long lasting exercise and training. In the years following the first symposium which was held in Brussels in 1968, biochemƯ istry of exercise has gained more importance in view of the increasing number of laboraƯ tories and scientific papers which are dealing with this field. From the topic of the first symposium - humoral modifications occurring during physical activity - our points of interest have been turned to a more limited area, namely long term exercise and training, It was important to investigate these subjects because everyone knows that in to-day's sport a good performance means hours of weekly or even daily training. Therefore, it was of considerable interest to stimulate discussions and to clarify ideas in this particular field of human activity. Our knowledge of biochemistry of exercise at the cellular level has highly progressed during the last five years. Researchers have focused their interests on the sequential utiƯ lization of fuels, the adaptative responses of the enzyme machinery, the different types of muscle fibers. The topics of the Proceedings include: general subjects, metabolism of carbohydrates, lipids, and proteins, hormonal regulations, electrolytes, ultrastructure and fiber types of muscle, cellular enzymes. In the symposium, the current knowledge was summarized as an introductory lecture to each of these topics by prominent authors, namely: J. KEuL (Freiburg i. Br.), M. ScHERRER (Bern), B. SAL TIN (Copenhagen), P