Meeting the Challenges of Blood Safety in the 21st Century: Pathogen Inactivation : Supplement Issue: Transfusion Medicine and Hemotherapy 2004, Vol. 31, Suppl. 1

Title from ebook title screen (viewed July 13, 2004). Contents......Page 3 References......Page 4 Introduction......Page 5 Transfusion of Pathogens......Page 6 Bacterial Contamination......Page 7 Viral Pathogens......Page 8 Transfusion of Residual Leukocytes......Page 10 Summary......Page 11 References......Page 12 Historical Perspective on Psoralens......Page 14 Sequence Specificity......Page 15 Adduct Frequency in the Actual PCT Process......Page 16 Effect of Inactivation on NAT......Page 17 References......Page 18 Introduction......Page 20 What Has Been Tested and Why?......Page 21 Safety Pharmacology and Acute Toxicity Studies......Page 22 Carcinogenicity Test......Page 23 Risk Assessment of Platelets Treated with the INTERCEPT Blood System......Page 24 Acknowledgement......Page 25 References......Page 26 Incidence......Page 27 Clinical Manifestation......Page 28 Gamma-Irradiation of Blood Components......Page 29 Dose of Gamma-Irradiation,Equipment,and Dosimetry......Page 30 Pathogen Inactivation as an Alternative to Gamma-Irradiation......Page 31 Conclusion......Page 32 References......Page 33 Background......Page 35 Residual Plasma in Platelet Concentrates......Page 36 Data Management and Quality Assurance......Page 37 Conclusion......Page 38 References......Page 39