Medical Management of Diabetes and Heart Disease (Clinical Guides to Medical Management)

This state-of-the-art reference details current and effective symptom-specific strategies for the diagnosis and management of diabetic patients-emphasizing the exploration of therapeutic options available for the treatment of accelerated coronary complications associated with diabetes. Addresses the pathophysiology underlying advanced heart disease and outlines treatments to impede progression in type 2 diabetic patients. Medical Management of Diabetes and Heart Disease contains the newest discoveries in • the relationship between diabetes and coronary illnesses • type 1 and type 2 diabetes • risk factors in diabetic patients for progressive heart disease • detection and diagnosis of insulin resistance and diabetes mellitus • nonpharmacological treatment and features the latest therapies in the treatment of coronary illnesses in diabetic subjects with • stable and unstable angina • acute myocardial infarction • congestive heart failure • percutaneous coronary intervention • coronary surgery With over 700 references and the contributions of more than 20 world-renowned experts, Medical Management of Diabetes and Heart Disease is an invaluable reference for primary care, family practice, and internal medicine physicians; cardiologists; cardiothoracic surgeons; endocrinologists; physician assistants; nurse practitioners; and medical students in these disciplines. Doody Review Services Reviewer: Lorraine R. Baer, Pharm.D.(Baer Communications, Ltd) Description: This book, one in the Medical Management series, provides a comprehensive review of diabetes and cardiovascular disease, with a focus on the pathophysiological role of insulin resistance. The book also provides clinically relevant supportive evidence, making it a valuable tool in therapeutic decision making. Purpose: The purpose is to provide a comprehensive understanding of the intimate relationship between diabetes and cardiovascular disease, with special emphasis on the pathopysiological links between these two complex conditions. The book also aims to provide clinical evidence for the prevention and treatment of the cardiac manifestations of insulin resistance. These objectives have important clinical significance and the authors provide an up-to-date review of the material. Audience: The book is suitable for general medical practitioners as well as trainees and specialists in the fields of endocrinology and cardiology. Medical students would find it a beneficial reference as well. Features: This is a current and comprehensive review of the complex relationship and pathophysiological links between diabetes and cardiovascular disease. There is clinically important emphasis on insulin resistance and its role in prediabetes, fibrinolysis, hyperlipidemia, hypertension, atherosclerosis, as well as polycystic ovary syndrome. The practical management of diabetic patients with hypertension, coronary artery disease, heart failure, dyslipidemia, as well as those with a need for coronary interventions is discussed. There is some discussion about the use of insulin secretagogues versus insulin sensitizers in patients with diabetes and cardiovascular disease, and how the BARI-2D study may help elucidate whether certain classes of drugs have a more favorable affect on the cardiovascular (or macrovascular) effects of diabetes. As to be expected with multiauthored books, there is some overlap. Overall, the book is excellent. Chapter 4 (Hypertension, Diabetes, and the Heart) is especially well-written and well-referenced. Only about half of the chapter authors reference the material they discuss, while the remainder simply provide a list of suggested readings. Although this does not detract from the credibility of the information, it makes it difficult to find sources for further investigation or use of the material. Assessment: Considering the worldwide epidemic of diabetes (expected to affect 300 million people in year 2025), this book will be a useful addition to the library of medical professionals caring for patients with diabetes or at risk for diabetes. The physical presentation makes the book easy to read and the tables are informative. Preface......Page 4 Contents......Page 6 Causal Connections......Page 12 Types of Diabetes and Their Implications Regarding Heart and Vascular Disease......Page 20 Recognition and Assessment of Insulin Resistance......Page 46 Hypertension, Diabetes, and the Heart......Page 76 Hyperlipidemia, Diabetes, and the Heart......Page 96 The Coagulation and Fibrinolytic Systems, Diabetes, and the Heart: Therapeutic Implications for Patients with Type 2 Diabetes......Page 116 Insulin Resistance, Compensatory Hyperinsulinemia, and Coronary Heart Disease: Syndrome X......Page 128 Detection and Diagnosis of Syndromes of Insulin Resistance and of Diabetes Mellitus......Page 148 Polycystic Ovary Syndrome, Insulin Resistance, and Cardiovascular Disease......Page 160 Detection and Diagnosis of Heart Disease in Diabetic and Prediabetic Subjects......Page 174 Treatment of Diabetes: Implications for Heart Disease......Page 188 Management of Patients with Diabetes and Coronary Artery Disease......Page 196 Pathophysiology and Management of Congestive Heart Failure in Patients with Diabetes Mellitus......Page 222 Special Therapeutic Considerations: Coronary Interventions and Coronary Surgery......Page 242 Nonpharmacological Reduction of Cardiovascular Risk......Page 270 Future Directions: Elucidation of Mechanisms as Targets for Therapy......Page 284 About the Editors......Page 292 Index......Page 294 This state-of-the-art reference details current and effective symptom-specific strategies for the diagnosis and management of diabetic patients-emphasizing the exploration of therapeutic options available for the treatment of accelerated coronary complications associated with diabetes. Addresses the pathophysiology underlying advanced heart disease and outlines treatments to impede progression in type 2 diabetic patients. Medical Management of Diabetes and Heart Disease contains the newest discoveries in the relationship between diabetes and coronary illnesses type 1 and type 2 diabetes risk factors in diabetic patients for progressive heart disease detection and diagnosis of insulin resistance and diabetes mellitus nonpharmacological treatment and features the latest therapies in the treatment of coronary illnesses in diabetic subjects with stable and unstable angina acute myocardial infarction congestive heart failure percutaneous coronary intervention coronary surgery With over 700 references and the contributions of more than 20 world-renowned experts, Medical Management of Diabetes and Heart Disease is an invaluable reference for primary care, family practice, and internal medicine physicians; cardiologists; cardiothoracic surgeons; endocrinologists; physician assistants; nurse practitioners; and medical students in these disciplines This book was inspired by cogent clinical observations and a rapidly expanding body of knowledge implicating diverse, specific, and sometimes paradoxical or unexpected factors in the pathogenesis of accelerated coronary artery disease associated with type 2 diabetes. This title details effective symptom-specific strategies for the diagnosis and management of diabetic patients. It emphasizes the exploration of therapeutic options available for the treatment of accelerated coronary complications associated with diabetes