Mechanisms Of Lymphocyte Activation And Immune Regulation X: Innate Immunity (advances In Experimental Medicine And Biology, Vol. 560)

Mechanisms of Lymphocyte Activation and Immune Regulation X: Innate Immunity is the proceedings of the Xth International Conference on Mechanisms of Lymphocyte Activation and Immune Regulation: Innate Immunity, held February 6-8, 2004 in Newport Beach, California. It is the tenth volume of its kind to appear in the series Advances in Experimental Medicine and Biology. Topics include toll receptors, dendritic cells, NK cells, and complement receptors. TIR Domain-Containing Adaptors Regulate TLR Signaling Pathways....Pages 1-9 Toll-Like Receptors: Linking Innate and Adaptive Immunity....Pages 11-18 Activation of Insect and Vertebrate Toll Signaling: From Endogenous Cytokine Ligand to Direct Recognition of Pathogen Patterns....Pages 19-27 Genetic Analysis of Innate Immunity: Identification and Function of the TIR Adapter Proteins....Pages 29-39 NF-κB, an Evolutionarily Conserved Mediator of Immune and Inflammatory Responses....Pages 41-45 Influence of KIR Diversity on Human Immunity....Pages 47-50 NKG2D in Innate and Adaptive Immunity....Pages 51-56 Specific and Non-Specific Natural Killer Cell Responses to Viral Infection....Pages 57-61 Antigen Processing and Presentation by Dendritic Cells: Cell Biological Mechanisms....Pages 63-67 Human Thymic Stromal Lymphopoietin Triggers Dendritic Cell-Mediated Allergic Inflammation and CD4+ T Cell Homeostatic Expansion....Pages 69-75 Role of TRAF6 in the Immune System....Pages 77-82 The Innate Functions of Dendritic Cells in Peripheral Lymphoid Tissues....Pages 83-97 The Mannose-Binding Lectin: An Infection Susceptibility Gene....Pages 99-103 Immunotherapy Via Dendritic Cells....Pages 105-114 Ontogeny of Lagerhans Cells and Graft Versus Host Disease....Pages 115-123 Role of the CD19 and CD21/35 Receptor Complex in Innate Immunity, Host Defense and Autoimmunity....Pages 125-139 Role of Complement Receptor 2 in the Pathogenesis of Systemic Lupus Erythematosus....Pages 141-147 Complement Regulation During Pregnancy....Pages 149-156 Against invading microorganisms, vertebrates including mammals develop innate immune systems, which are activated by microbial components possessing conserved structures called pathogen associated molecular patterns (PAMPs); including bacterial cell wall components, and viral genomic DNA and RNA. This volume is edited by Dr. Sudhir Gupta, internationally recognized expert in Immunology, Professor of Medicine, Pathology, Microbiology and Molecular Genetics. Topics include toll receptors, dendritic cells, NK cells, and complement receptors.