Mechanics of Biological Systems and Materials, Volume 7: Proceedings of the 2014 Annual Conference on Experimental and Applied Mechanics (Conference Proceedings ... Society for Experimental Mechanics Series)

__Mechanics of Biological Systems and Materials____, Volume 7: Proceedings of the 2014 Annual Conference on Experimental and Applied Mechanics__, the seventh volume of eight from the Conference, brings together contributions to this important area of research and engineering. The collection presents early findings and case studies on a wide range of areas, including: Soft Tissues Mechanics Natural Materials & Bio-Inspiration Tissue Engineering Cells Mechanics Preface 6 Contents 8 Chapter 1: In Vitro Complex Shear Modulus of Bovine Muscle Tissue 9 1.1 Introduction 9 1.2 Experimental Method 11 1.3 Results and Discussion 12 1.4 Conclusions 14 References 14 Chapter 2: A Camera-Based Experimental Method for Mechanical Test on Patellar Tendons 15 2.1 Introduction 15 2.2 Experimental Set Up and Measurement Procedure 16 2.3 Materials and Methods 18 2.4 Experimental Results 21 2.5 Conclusions 24 References 24 Chapter 3: Thin-Shell Behavior of Mammalian Tympanic Membrane Studied by Digital Holography 26 3.1 Introduction 26 3.2 Thin-Shell Modeling of the TM 27 3.3 Methods to Test the Thin-Shell Theory 28 3.3.1 Shape Measurements 28 3.3.2 3D Displacement Measurements 29 3.4 Results Through Test and Validation of the Thin-Shell Theory 30 3.4.1 Comparisons of the 3D Motion of the TM 30 3.4.2 Resultant Sound-Induced Displacements 30 3.5 Conclusions 31 References 14 Chapter 4: Controlling Abalone Shell Architecture with Temperature 33 4.1 Introduction 33 4.2 Experimental Procedure 34 4.3 Results and Discussion 35 4.4 Conclusions 36 References 37 Chapter 5: The Modeling of Time Dependent Mechanical Properties of Cervine Enamel 38 5.1 Introduction 38 5.2 Material and Methods 39 5.3 Results and Discussion 40 5.4 Conclusion 41 References 41 Chapter 6: Development of Tissue Surrogates for Photoelastic Strain Analysis of Needle Insertion 42 6.1 Introduction 42 6.2 Mechanical Properties of Tissue 43 6.3 Development of a Surrogate Tissue Material 44 6.3.1 Transparency and Birefringence 45 6.3.2 Resistance to Tearing When Punctured 45 6.3.3 Performance Under Load 46 6.3.4 Discussion of Surrogate Material Experiments 46 6.4 Puncture Experiments 47 6.4.1 Phase I: Boundary Displacement 47 6.4.2 Phase II: Tip Insertion 47 6.4.3 Phase III: Tip and Shaft Insertion 48 6.4.4 Puncture Test Procedure 48 6.4.5 Discussion of Puncture Test 48 6.5 Closing Remarks 49 References 49 Chapter 7: Polymer Gels for Defense Applications 51 7.1 Introduction 51 7.2 Experimental 52 7.3 Results and Discussion 52 7.4 Conclusions 54 References 55 Chapter 8: Development of a Microloading Platform for In Vitro Mechanotransduction Studies 56 8.1 Introduction 56 8.2 Methods and Results 57 8.2.1 Development and Characterization of Microloading Platform 57 8.3 Microloading Platform Alignment 59 8.4 PDMS Fabrication 59 8.5 Finite Element Analysis of PDMS Well 59 8.6 Cell Culture 61 8.7 Loading Induced Differential Activity 61 8.8 Discussion 62 References 62 Chapter 9: Development of a Multi-Strain Profile for Cellular Mechanotransduction Testing 63 9.1 Introduction 63 9.2 Experimental Procedure 64 9.2.1 Profile Design 64 9.2.2 Fabrication 65 9.2.3 FEA 65 9.2.4 Physical Test 66 9.3 Results 66 9.3.1 FEA 66 9.3.2 Physical Test 66 9.4 Discussion 68 References 69 Chapter 10: Pull-Off Adhesion Measurements on C. Elegans 70 10.1 Introduction 70 10.2 Experimental Methods 71 10.2.1 C. elegans Growth and Maintenance 71 10.2.2 Experimental Setup 71 10.2.3 Agar Pad Production 71 10.2.4 Pull-Off Experiment 71 10.3 Model 72 10.4 Results and Discussion 73 10.5 Conclusions 74 References 74 Chapter 11: A Fractional Order Model for Local Electric Fields in Tissues 76 11.1 Introduction 76 11.2 Mathematical Model 77 11.3 Results 78 11.4 Conclusion 80 References 80 Chapter 12: Simulation of Atherosclerotic Plaque Delamination Using the Cohesive Zone Model 81 12.1 Introduction 81 12.2 Material Model 82 12.2.1 Bulk Material for the Mouse Aorta 82 12.2.2 Cohesive Model 83 12.3 Numerical Simulations of Atherosclerotic Plaque Delamination 84 12.3.1 Experimental Process and Simulation Model 84 12.3.2 Parameter Identification 85 12.3.2.1 Material Properties of Holzapfel Model 85 12.3.2.2 CZM Material Properties 86 12.4 Prediction and Validation 87 12.5 Conclusions 87 References 88 Front Matter....Pages i-vii In Vitro Complex Shear Modulus of Bovine Muscle Tissue....Pages 1-6 A Camera-Based Experimental Method for Mechanical Test on Patellar Tendons....Pages 7-17 Thin-Shell Behavior of Mammalian Tympanic Membrane Studied by Digital Holography....Pages 19-25 Controlling Abalone Shell Architecture with Temperature....Pages 27-31 The Modeling of Time Dependent Mechanical Properties of Cervine Enamel....Pages 33-36 Development of Tissue Surrogates for Photoelastic Strain Analysis of Needle Insertion....Pages 37-45 Polymer Gels for Defense Applications....Pages 47-51 Development of a Microloading Platform for In Vitro Mechanotransduction Studies....Pages 53-59 Development of a Multi-Strain Profile for Cellular Mechanotransduction Testing....Pages 61-67 Pull-Off Adhesion Measurements on C. Elegans ....Pages 69-74 A Fractional Order Model for Local Electric Fields in Tissues....Pages 75-79 Simulation of Atherosclerotic Plaque Delamination Using the Cohesive Zone Model....Pages 81-88 MEMS and Nanotechnology, Volume 8: Proceedings of the 2014 Annual Conference on Experimental and Applied Mechanics, the eighth volume of eight from the Conference, brings together contributions to this important area of research and engineering.