Marine Physiology Down East: The Story of the Mt. Desert Island Biological Laboratory (Perspectives in Physiology)

This volume offers a comprehensive history of the Mount Desert Island Biological Laboratory (MDIBL), one of the major marine laboratories in the United States and a leader in using marine organisms to study fundamental physiological concepts. Beginning with its founding as the Harpswell Laboratory of Tufts University in 1898, David H. Evans follows its evolution from a teaching facility to a research center for distinguished renal and epithelial physiologists. He also describes how it became the site of major advances in cytokinesis, regeneration, cardiac and vascular physiology, hepatic physiology, endocrinology and toxicology, as well as studies of the comparative physiology of marine organisms. Fundamental physiological concepts in the context of the discoveries made at the MDIBL are explained and the social and administrative history of this renowned facility is described. Front Matter....Pages i-xix Beginnings at Harpswell, Maine....Pages 1-37 Early Years on Mount Desert Island: The First Generation....Pages 39-86 The Second Generation: MDIBL in the 1930s....Pages 87-140 Wartime and the Early Postwar Years: Bust and Boom at the MDIBL....Pages 141-184 MDIBL in the Postwar: The Third Generation....Pages 185-244 Mid Century: The Third-Generation Redux....Pages 245-318 Year-Round Operation: The First Attempt....Pages 319-380 Research in the 1970s: The Fourth Generation....Pages 381-457 MDIBL in the 1980s: Doors Close, Doors Open....Pages 459-505 Research in the 1980s: The Fifth Generation....Pages 507-595 The Centennial Decade of the MDIBL....Pages 597-731 Research in the 1990s: Molecular Biology Comes to the MDIBL....Pages 733-792 The MDIBL in the Early Twenty-First Century: A New Beginning....Pages 793-993 Research in the Early Twenty-First Century: The Year-Round Research Program Comes of Age....Pages 995-1064 Back Matter....Pages 1065-1094