Management of Early Stage Breast Cancer : Basics and Controversies

Breast cancer, its causes, early detection and treatment have received considerable attention, since this widespread disease is one of the most important health concerns for women. This book provides a comprehensive overview of the diagnostic and therapeutic aspects of the management of early-stage breast cancer, including essential information on basic topics like pathology, and radiology, as well as the latest developments. Further, it discusses all aspects of surgical care, chemotherapy and radiation therapy, together with the controversies and current management guidelines. Helping readers acquire a deep, holistic understanding of the topic, the book is a valuable resource for practitioners and postgraduate students in the field of gynecologic oncology. Moreover, it is a useful aid to decision-making in day-to-day practice for oncologists, residents, fellows and experienced practitioners. Front Matter ....Pages i-xx Breast Cancer Trends: Global and Indian Scenario (P. Gangadharan, Ajil Shaji, D. K. Vijaykumar, Beena Kunheri)....Pages 1-13 Role of Screening: Guidelines and Recommendations (Sanjay Hunugundmath, Anjali Menon, Beena Kunheri)....Pages 15-21 Imaging: Controversies and Interventions in Early Breast Cancer (Janaki P. Dharmarajan)....Pages 23-41 Pathology of Early Breast Carcinomas (Ajith Nambiar)....Pages 43-57 Molecular Mechanisms of Early Breast Cancer (Prasanth Ariyannur, Vijay Kumar Srinivasalu)....Pages 59-83 Surgical Management of Early Breast Cancer (Misha J. C. Babu)....Pages 85-91 Sentinel Lymph Node in Early Breast Cancer: Evidence, Techniques, and Controversies (Sheikh Zahoor Ahmad, D. K. Vijaykumar)....Pages 93-118 Oncoplastic Surgery in Early Breast Cancer (Arun Peter Mathew)....Pages 119-130 Risk Stratification for Adjuvant Treatment in Early Breast Cancer (Wesley M. Jose)....Pages 131-142 Adjuvant Chemotherapy in Early Breast Cancer (Arun Philip)....Pages 143-155 Role of Anti-HER2/Neu Molecules in the Management of HER2-Positive Early Breast Cancer (K. Pavithran)....Pages 157-163 Adjuvant Endocrine Therapy in Early Breast Cancer (Ashok S. Komaranchath)....Pages 165-177 Ductal Carcinoma In Situ: Current Consensus in Management (Vineeta Goel, Deepti Sharma)....Pages 179-193 Radiation Treatment in Early Breast Cancer: An Overview (Anand Radhakrishnan, Beena Kunheri, Kurian Joseph)....Pages 195-201 Breast Radiation Therapy Techniques (Vishnu R. Nambiar, Haridas M, Dinesh Makuny, Beena Kunheri)....Pages 203-215 Role of Radiation Therapy in Early Breast Cancer Patients with One to Three Pathological Nodes (Vishnu R. Nambiar, Ram Madhavan, Beena Kunheri)....Pages 217-225 Regional Nodal Irradiation in Early Breast Cancer (Shyama Sudha Prem, Shiva Kumar Siripuram, Pragna Sagar Rapole)....Pages 227-241 Hypofractionation: Evidence, Rationale, and Practice (Sanjiv Sharma)....Pages 243-252 Accelerated Partial-Breast Irradiation: Current Evidence and Techniques (Sruthi Kalavagunta, Beena Kunheri)....Pages 253-263 Psychological Impact of Breast Cancer Diagnosis and Treatment: The Role of Psychooncology (Gilsa K. Gopinadhan, Koravangattu Valsraj, Beena Kunheri)....Pages 265-276