Management Of Bladder Cancer: A Comprehensive Text With Clinical Scenarios Management Of Bladder Cancer (konety)

__Management of bladder cancer__ provides a single, comprehensive reference source that incorporates all the latest information regarding bladder cancer. The text covers epidemiology and natural history of bladder cancer as well as latest findings regarding the genetics and molecular biology of the disease. Diagnostic and staging evaluation of both non-muscle invasive and invasive bladder cancer is discussed. The text incorporates chapters summarizing new findings regarding markers for the diagnosis of bladder cancer and new diagnostic techniques to enhance traditional methods such as cystoscopy. Risk stratified treatment of non muscle invasive bladder cancer including various approaches to intravesical therapy are reviewed. Current guideline based approaches to management and new data regarding diagnosis and prognostication of muscle invasive bladder cancer is analyzed and summarized. The application of chemotherapy for muscle invasive and advanced disease is discussed and the evidence based application of multimodality therapy highlighted. Finally, gaps in current knowledge and areas for future research are highlighted. Ongoing important clinical trials which could imminently yield significant new knowledge is discussed. Authored by experts in their respective fields, __Management of Bladder Cancer__ will serve as a easy and complete reference source for clinicians, researchers, individuals in training, allied health professionals and medical students in the fields of Urology, Medical Oncology, Radiation Oncology, Basic and Translational Science and Epidemiology. Front Matter....Pages i-xx Front Matter....Pages 1-1 Epidemiology and Natural History....Pages 3-16 Screening for Bladder Cancer....Pages 17-29 Pathology and Staging: Histopathology and Cytopathology....Pages 31-44 Pathology and Staging: Genetics and Molecular Biology....Pages 45-57 Imaging in Localized and Advanced Bladder Cancer....Pages 59-71 New Imaging Techniques in the Staging of Urothelial Carcinoma of the Bladder....Pages 73-83 Socioeconomic Issues and Improved Quality of Care....Pages 85-94 Quality of Life Measures....Pages 95-110 Prognostication and Risk Assessment....Pages 111-143 Clinical Trials and Emerging Therapeutic Strategies in Bladder Cancer....Pages 145-152 Front Matter....Pages 153-153 Improved Diagnostic Techniques....Pages 155-170 Clinical Scenario: Microscopic Hematuria and Atypical Cytology....Pages 171-177 Localized Surgical Therapy and Surveillance....Pages 179-190 Clinical Scenario: Initial High-Grade Ta Tumor....Pages 191-200 Clinical Scenario: Recurrent Ta Tumor....Pages 201-207 Clinical Scenario: Rapidly Growing, High Volume, Low-Grade Ta Tumor....Pages 209-214 Clinical Scenario: Low-Grade T1 Tumor....Pages 215-221 Intravesical Therapy....Pages 223-238 Clinical Scenario: Initial CIS....Pages 239-243 Management of BCG Recurrent Bladder Cancer....Pages 245-263 Front Matter....Pages 153-153 Clinical Scenario: Persistent CIS and High-Grade Ta Bladder Cancer After BCG....Pages 265-269 Clinical Scenario: Management of Side Effects from Bacillus Calmette-Guérin Bladder Instillation....Pages 271-276 Guideline-Based Management of Non-muscle Invasive Bladder Cancer: Comparison of the AUA, EAU, ICUD, and NCCN Guidelines....Pages 277-289 Front Matter....Pages 291-291 Open Radical Cystectomy....Pages 293-308 Robotic Cystectomy....Pages 309-325 Clinical Scenario: T2 Bladder Tumor....Pages 327-336 Urinary Diversion: Open and Robotic Techniques....Pages 337-359 Chemoradiotherapy....Pages 361-377 Clinical Scenario: Bladder Preservation....Pages 379-386 Management of Bladder Cancer, Role of Chemotherapy and Controversies Surrounding Its Application....Pages 387-403 Clinical Scenario: Large Volume, Non-metastatic T2 Bladder Tumor....Pages 405-409 The Role of Pelvic Lymphadenectomy at the Time of Radical Cystectomy for Bladder Cancer....Pages 411-421 Clinical Scenario: Unexpected Positive Nodes at Radical Cystectomy....Pages 423-427 Surveillance and Monitoring....Pages 429-439 Clinical Scenario: The Role of Perioperative Chemotherapy....Pages 441-447 Clinical Scenario: Clinical Pelvic Nodal Metastases After Complete Response to Chemotherapy....Pages 449-455 Guideline-Based Management of Muscle-Invasive Bladder Cancer: NCCN, ICUD, and EAU....Pages 457-463 Back Matter....Pages 465-479 Epidemiology and natural history Screening for Bladder Cancer Pathology and Staging: Histopathology and Cytopathology Pathology and Staging: Genetics and Molecular Biology Imaging in Localized and Advanced Bladder Cancer New Imaging Techniques in Staging of Urothelial Carcinoma of the Bladder Socioeconomic issues and improved quality of care Quality of life measures Prognostication and risk assessment Clinical trials and emerging therapeutic strategies in bladder cancer Improved diagnostic techniques Clinical scenario: Microscopic hematuria and atypical cytology in a 68 year old man with normal upper tract imaging Localized surgical therapy and surveillance Clinical Scenario: Initial high grade Ta tumor Clinical Scenario: Recurrent Ta tumor Clinical Scenario: Rapidly growing, high volume, low grade Ta tumor Clinical Scenario: Low grade T1 tumor Intravesical therapy Clinical Scenario: Initial CIS Management of BCG Recurrent Bladder Cancer Clinical Scenario: Persistent CIS and HIGH Grade Ta Bladder Cancer after BCG Maurizio Brausi Clinical Scenario: Presentation and Management of Significant Side Effects from Bacillus Calmette-Guérin Bladder Instillation Guideline-based management of non-muscle invasive bladder cancer: comparison of the AUA, EAU, ICUD and NCCN guidelines Open Radical Cystectomy Robotic cystectomy Clinical Scenario: T2 bladder tumor Urinary Diversion: Open and robotic techniques Chemoradiotherapy Clinical Scenario: 53 year-old man with a solitary, 2 cm, high-grade T2 tumor and focal CIS in the bladder dome who wants bladder preservation Management of Bladder Cancer, role of chemotherapy and controversies surrounding its application Clinical Scenario: Large volume, non metastatic T2 bladder tumor The role of pelvic lymphadenectomy at the time of radical cystectomy for bladder cancer Clinical Scenario: Unexpected positive nodes at radical cystectomy Surveillance and monitoring Clinical Scenario: The Role of Perioperative Chemotherapy Management of Bladder Cancer with Pelvic Nodal Metastases After Complete Response to Chemotherapy Guideline based management muscle-invasive bladder cancer: NCCN, ICUD and EAU. This book provides a single, comprehensive reference source that incorporates the epidemiology, natural history, and the latest genetic and molecular biological findings of bladder cancer. This book discusses the diagnostic and staging evaluation of both non-muscle invasive and invasive bladder cancer and incorporates the new findings on markers for the diagnosis of bladder cancer. Risk stratified treatment of non-muscle invasive bladder cancer including various approaches to intravesical therapy are reviewed. Current guideline-based approaches to management and new data regarding diagnosis and prognostication of muscle invasive bladder cancer is analyzed and summarized. This book covers the application of chemotherapy for muscle invasive and advanced disease. The evidence-based application of multimodality therapy is highlighted. Gaps in current knowledge and important areas for clinical research are highlighted. Authored by experts in their respective fields, Management of Bladder Cancer: A Comprehensive Text with Clinical Scenarios serves as an easy and complete reference source for clinicians, researchers, individuals in training, allied health professionals and medical students in the fields of Urology, Medical Oncology, Radiation Oncology, Basic and Translational Science and Epidemiology. -- Source other than Library of Congress