Management of Antimicrobials in Infectious Diseases: Impact of Antibiotic Resistance (Infectious Disease)

Arch Mainous III, PhD, Claire Pomeroy, MD, and a panel of experienced physicians offer an eminently practical summary of the most effective evidence-based antimicrobial treatments encountered in both hospital and outpatient settings. Focusing on the clinical impact of appropriate diagnosis and treatment, the book emphasizes those newer aspects of infectious disease management necessitated by the growing problem of antibiotic resistance. It also discusses the major pathogens involved so that practicing clinicians will not only diagnose, but also better treat the infections and complications they cause. Multidisciplinary and highly practical, Management of Antimicrobials in Infectious Diseases: Impact of Antibiotic Resistance offers busy clinicians and nurse practitioners a comprehensive and informed guide to navigating the difficult treatment decisions created by the rising tide of antibiotic resistance today. Optimal antimicrobial use is essential in this era of escalating antibiotic resistance. Clinicians, particularly those on the frontlines of care, need an understanding of the management of common infectious diseases and the appropriate use of antimicrobials in the context of resistant pathogens. In Management of Antimicrobials in Infectious Diseases, Arch Mainous, PhD and Claire Pomeroy, MD and a group of antimicrobial experts and experienced clinicians provide an eminently practical summary of the most effective evidence-based antimicrobial treatments encountered in both the hospital and outpatient settings. At the forefront of this book is the clinical impact of appropriate diagnosis and treatment, as well as an emphasis on the newer aspects of infectious disease management necessitated by the increasing problem of resistant pathogens. Further, the book provides useful information on major pathogens to help practicing clinicians not only diagnose but treat effectively infections and their concomitant complications. Multidisciplinary and highly practical, Management of Antimicrobials in Infectious Diseases offers busy clinicians, nurse practitioners, as well as residents and medical students a comprehensive and informed guide for management and treatment in the contemporary environment fraught with resistant pathogens Management of Antimicrobials in Infectious Diseases......Page 4 Preface......Page 8 Contents......Page 10 List of Contributors......Page 14 I Introduction......Page 16 1 Antibiotic Resistance and Implications for the Appropriate Use of Antimicrobial Agents......Page 18 II Significant Pathogens......Page 42 2 Gram-Positive Bacteria......Page 44 3 Gram-Negative Bacteria......Page 58 4 Viruses......Page 76 5 Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome......Page 100 6 Fungal Infections......Page 116 III Management of Infectious Diseases......Page 140 7 Upper Respiratory Infections and Acute Bronchitis......Page 142 8 Diagnosis and Management of Pneumonia......Page 158 9 Tuberculosis......Page 172 10 Current Cost-Effective Management of Urinary Tract Infections......Page 186 11 Sexually Transmitted Diseases......Page 200 12 Gastrointestinal Tract Infections......Page 232 13 Endocarditis......Page 254 14 Infections of the Central Nervous System......Page 268 15 Common Infections of the Skin and Bone......Page 288 IV Special Considerations......Page 304 16 Strategies for Optimal Antimicrobial Use......Page 306 17 Antimicrobial Resistant Flora in the Hospital......Page 322 18 Infections in the Immunocompromised Host......Page 330 19 Future Trends in Antimicrobial Use......Page 346 Index......Page 356 Humana Press Management of Antimicrobials in Infectious Diseases 4 Preface 8 Contents 10 List of Contributors 14 I Introduction 16 1 Antibiotic Resistance and Implications for the Appropriate Use of Antimicrobial Agents 18 II Significant Pathogens 42 2 Gram-Positive Bacteria 44 3 Gram-Negative Bacteria 58 4 Viruses 76 5 Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome 100 6 Fungal Infections 116 III Management of Infectious Diseases 140 7 Upper Respiratory Infections and Acute Bronchitis 142 8 Diagnosis and Management of Pneumonia 158 9 Tuberculosis 172 10 Current Cost-Effective Management of Urinary Tract Infections 186 11 Sexually Transmitted Diseases 200 12 Gastrointestinal Tract Infections 232 13 Endocarditis 254 14 Infections of the Central Nervous System 268 15 Common Infections of the Skin and Bone 288 IV Special Considerations 304 16 Strategies for Optimal Antimicrobial Use 306 17 Antimicrobial Resistant Flora in the Hospital 322 18 Infections in the Immunocompromised Host 330 19 Future Trends in Antimicrobial Use 346 Index 356 ISBN-13:,9780896038219 US physicians, most from Kentucky and South Carolina, summarize the most effective evidence-based antimicrobial treatments encountered in both hospital and outpatient settings, for practical use by general and specialist clinicians and nurse practitioners. The development of antibiotics completely revolutionized medicine in the second half of the 20th century.