Management of Acute Coronary Syndromes (Contemporary Cardiology)

A path-breaking and comprehensive review of the pathophysiology and management of patients with acute coronary syndromes (ACS). Drawing on the key results of recent clinical trials, world-renowned clinicians and clinical investigators establish state-of-the-art management guidelines for patients with ST-elevation MI or non-ST-elevation ACS. Their discussion includes a detailed review of the pathophysiology of ACS and a survey of the diagnostic tools available to assess patients. Management of Acute Coronary Syndromes captures the major advances that have occurred in our understanding of the pathophysiology, diagnosis, and management of patients with acute coronary syndromes. This book is certain to help cardiologists, primary physicians, emergency medicine physicians, and many others to better serve their patients with today's most efficacious treatments. Front Matter....Pages i-xv Front Matter....Pages 1-1 The Spectrum of Myocardial Ischemia....Pages 3-18 Linking Biochemical, Pathologic, and Clinical Events in Acute Coronary Syndromes....Pages 19-56 Triggers of Acute Coronary Syndromes....Pages 57-85 Insights into the Pathophysiology of Acute Coronary Syndromes Using the TIMI Flow Grade and TIMI Frame Counting Methods....Pages 87-107 Front Matter....Pages 109-109 Identifying Acute Cardiac Ischemia in the Emergency Department....Pages 111-133 Early Identification and Treatment of Patients with Acute Coronary Syndromes....Pages 135-145 Serum Markers for Diagnosis and Risk Stratification in Acute Coronary Syndromes....Pages 147-171 Technologies to Diagnose Acute Ischemia....Pages 173-197 Front Matter....Pages 199-199 Thrombolytic Therapy for Acute Myocardial Infarction With ST-Segment Elevation....Pages 201-241 New Thrombolytic Agents....Pages 243-265 Primary Angioplasty....Pages 267-291 Antiplatelet and Antithrombotic Therapy....Pages 293-336 β-Adrenergic Blockers, Calcium Channel Blockers, and Nitrates....Pages 337-356 Angiotensin-Converting Enzyme Inhibitors in Acute Coronary Syndromes....Pages 357-382 Risk Stratification: Exercise Testing, Imaging, and Cardiac Catheterization....Pages 383-405 Front Matter....Pages 407-407 Antithrombotic Therapy in Unstable Angina and Non-Q-Wave Myocardial Infarction....Pages 409-423 Novel Antiplatelet and Antithrombotic Agents in the Treatment of Non-ST-Segment Elevation Coronary Ischemia....Pages 425-462 Thrombolytics and Invasive vs Conservative Strategies....Pages 463-475 New Device Strategies in the Management of Acute Coronary Syndromes....Pages 477-496 Front Matter....Pages 497-497 Women and Acute Coronary Syndromes....Pages 499-520 Front Matter....Pages 497-497 Myocardial Infarction in the Younger Patient....Pages 521-533 Aggressive Management of Cardiogenic Shock....Pages 535-569 Cholesterol Lowering....Pages 571-592 Secondary Prevention of Myocardial Infarction....Pages 593-600 Cost-Effectiveness Analysis and the Treatment of Acute Coronary Syndromes....Pages 601-610 Critical Pathways for Acute Coronary Syndromes....Pages 611-627 Back Matter....Pages 629-660 In Management of Acute Coronary Syndromes, Christopher Cannon has brought together a highly experienced group of clinical investigators who succinctly yet comprehensively review the pathophysiology and management of patients with acute coronary syndromes (ACS). Drawing on the key results of recent clinical trials, these world-renowned experts establish state-of-the-art management guidelines for patients with ST-elevation MI or non-ST-elevation ACS. Their discussion includes a detailed review of the pathophysiology of ACS and a survey of the diagnostic tools available to assess patients. They also examine special concerns in ACS, such as the unique issues in women, with cholesterol lowering, and cost-effectiveness. Management of Acute Coronary Syndromes captures the major advances that have occurred in our understanding of the pathophysiology, diagnosis, and management of patients with acute coronary syndromes. This book-the new gold standard for ACS management-is certain to help cardiologists, internists, primary care physicians, emergency medicine physicians, fellows, house staff, and students to better serve their patients with today's most efficacious treatments Twenty-six articles draw on recent results of clinical trials to explain guidelines for patients with ST- and non-ST- elevation myocardial ischemia (MI), as well as to explore the pathophysiology and diagnosis of acute coronary syndrome (ACS). Subjects include information on thrombolytic therapy, risk stratification, antiplatelet and antithrombotic agents, a comparison of invasive versus conservative strategies, and primary angioplasty. A final section deals with special issues such as ACS and women, MI in younger patients, cardiogenic shock, cholesterol lowering, cost-effectiveness analysis in treatment, and secondary prevention of MI. Annotation copyrighted by Book News, Inc., Portland, OR Defining and illustrating the new paradigm of acute coronary syndromes, this text presents the management of disease including aggressive thrombolytic, andithrombotic and interventional approaches. Edited By Christopher P. Cannon ; Foreword By Eugene Braunwald. Includes Index. Includes Bibliographical References And Index.